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| Product | Description | |
|---|---|---|
| LM11A-31 | LM11A-31, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 102562-74-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-117088. |  |
| LM11A-31 | LM11A-31 Inhibitor. Uses: Scientific use. Product Category: T11861. CAS No. 1243259-19-9. |  |
| LM11A-31 dihydrochloride | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| LM11A-31 dihydrochloride | LM11A-31 dihydrochloride, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 dihydrochloride is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 dihydrochloride reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1243259-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-110155. | |
| LM11A-31 HCl | LM11A-31 is a small-molecule p75NTR modulator and proNGF antagonist, in preventing diabetes-induced BRB breakdown. Targeting p75NTR signalling using LM11A-31, an orally bioavailable receptor modulator, may offer an effective, safe and non-invasive therapeutic strategy for treating macular oedema, a major cause of blindness in diabetes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: LM11A-31 HCl; LM11A-31 hydrochloride; LM11A-31; LM11A 31; LM11A31; LM 11A-31; LM 11A31; LM-11A-31. Product Category: Antagonists. Appearance: Solid powder. CAS No. 1243259-19-9. Molecular formula: C12H27Cl2N3O2. Mole weight: 316.27. Purity: >96%. IUPACName: (2S,3S)-2-amino-3-methyl-N-[2-(4-morpholinyl)ethyl]-pentanamide, dihydrochloride. Canonical SMILES: CC[C@H](C)[C@H](N)C(NCCN1CCOCC1)=O.[H]Cl.[H]Cl. Product ID: ACM1243259199. Alfa Chemistry ISO 9001:2015 Certified. |  |
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