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| Product | Description | |
|---|---|---|
| Locostatin | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Locostatin | Locostatin is a cell-permeable N-(crotonyl)oxazolidinone compound that acts as a potent inhibitor of RKIP (Raf kinase inhibitor protein)/Raf-1 kinase interaction. Synonyms: (S)-4-Benzyl-3-(but-2-enoyl)oxazolidin-2-one; (N-Crotonyl)-(4S)-benzyl-2-oxazolidinone. Grades: 95%. CAS No. 133812-16-5. Molecular formula: C14H15NO3. Mole weight: 245.27. |  |
| Locostatin | Locostatin (UIC-1005) is a potent RKIP inhibitor. Locostatin binds Raf kinase inhibitor RKIP protein and disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. Locostatin inhibits cell proliferation and migration. Locostatin can be used to synthesize chemical probes toward PEBP-proteins. Locostatin aggravates thioacetamide (HY-Y0698)-induced acute liver failure in mice [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UIC-1005. CAS No. 90719-30-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-W013411A. |  |
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