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Lofepramine Lofepramine (Lopramine) is a modified tricyclic and orally active antidepressant. Lofepramine inhibits the uptake of Noradrenaline (NA) (HY-13715) and 5-hydroxytryptamine (5-HT) with IC 50 s of 2.7 μM and 11 μM, respectively. Lofepramine exerts its antidepressant activity by promoting noradrenergic neurotransmission. Lofepramine also enhances serotonergic neurotransmission by inhibiting neuronal uptake of 5-HT and tryptophan pyrrolase. Lofepramine exhibits significant anxiolytic properties. [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lopramine. CAS No. 23047-25-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12390. MedChemExpress MCE
Lofepramine Psychotropic drug related to imipramine. Antidepressant. Group: Biochemicals. Alternative Names: 1- (4-Chlorophenyl) -2- [ [3- (10, 11-dihydro-5H-dibenz [b, f] azepin-5-yl) propyl] methylamino] ethanone; 4'-Chloro-2- [ [3- (10, 11-dihydro-5H-dibenz [b, f] azepin-5-yl) propyl-methylamino] acetophenone. Grades: Highly Purified. CAS No. 23047-25-8. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
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