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| Product | Description | |
|---|---|---|
| Lomeguatrib | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Lomeguatrib | Lomeguatrib, also known as PaTrin-2, is a potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase. Lomeguatrib is also a nontoxic low-molecular weight pseudosubstrate that has the ability to inactivate MGMT. Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment. Synonyms: PaTrin 2; PaTrin2; PaTrin-2; Lomeguatrib; Patrin. O6-(4-bromothenyl)guanine; 6-(4-Bromothenyloxy)-7H-purin-2-amine. CAS No. 192441-08-0. Molecular formula: C10H8BrN5OS. Mole weight: 326.172. |  |
| Lomeguatrib | Lomeguatrib is an inhibitor of O6-methylguanine-DNA methyltransferase (MGMT). Lomeguatrib attenuates MGMT activity in vitro and in vivo. Lomeguatrib enhances the antitumor activity of temozolomide in both human melanoma and MCF-7 xenografts. Group: Biochemicals. Alternative Names: 6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine; 6-[(4-Bromo-2-thienyl)methoxy]-1H-purin-2-amine; 2-Amino-6-(4-bromothiophen-2-ylmethoxy)-9H-purine; PaTrin 2. Grades: Highly Purified. CAS No. 192441-08-0. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
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