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LQZ-7I LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of this work. LQZ-7 when given orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors. The data obtained utilizing LQZ-7I in both in vitro and in vivo studies highlights its potential as a lead for further development, which may yield a potential cancer therapeutic by targeting the survivin protein directly. Uses: Designed for use in research and industrial production. Additional or Alternative Names: LQZ-7I; LQZ 7I; LQZ7I. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 195822-23-2. Molecular formula: C20H14F2N4. Mole weight: 348.36. Purity: >98%. IUPACName: 2,3-Quinoxalinediamine, N,N'-bis(4-fluorophenyl)-. Canonical SMILES: FC1=CC=C(NC2=NC3=CC=CC=C3N=C2NC4=CC=C(F)C=C4)C=C1. Product ID: ACM195822232. Alfa Chemistry — ISO 9001:2015 Certified. Categories: N2,N3-bis(4-fluorophenyl)quinoxaline-2,3-diamine. Alfa Chemistry.
LQZ-7I LQZ-7I is a survivin targeted inhibitor that can inhibit the growth of xenograft tumors and induce the loss of survivin in the tumor. Synonyms: N2,N3-Bis(4-Fluorophenyl)Quinoxaline-2,3-Diamine; N,N'-Bis(4-Fluorophenyl)Quinoxaline-2,3-Diamine. Grades: 98%. CAS No. 195822-23-2. Molecular formula: C20H14F2N4. Mole weight: 348.3. BOC Sciences 9

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