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| Product | Description | |
|---|---|---|
| Lumacaftor | Lumacaftor is the second investigational oral candidate compound for the treatment of cystic fibrosis (CF). Lumacaftor may act to restore the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, the defective cell membrane protein responsible for the progression of CF. Lumacaftor defects in the CFTR protein affect the transport of chloride and other ions across cells, and lead to the accumulation of thick, sticky mucus in the lungs of patients with CF. This mucus fosters chronic infection and inflammation, and results in irreversible lung damage. Synonyms: VX-809; VX809; VX 809; VRT 826809; VRT826809; VRT-826809. Grades: ≥98%. CAS No. 936727-05-8. Molecular formula: C24H18F2N2O5. Mole weight: 452.41. |  |
| Lumacaftor | Lumacaftor (VX-809; VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-809; VRT 826809. CAS No. 936727-05-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13262. |  |
| VX-809 (Lumacaftor) | VX-809 (Lumacaftor). Group: Biochemicals. Alternative Names: 3- [6- [ [ [1- (2, 2-Difluoro-1, 3-benzodioxol-5-yl) cyclopropyl] carbonyl] amino] -3-methyl-2-pyridinyl] benzoic Acid; Lumacaftor; VRT 826809. Grades: Highly Purified. CAS No. 936727-05-8. Pack Sizes: 50mg, 100mg, 250mg. Molecular Formula: C??H??F?N?O?, Molecular Weight: 452.51. US Biological Life Sciences. |  Worldwide |
| 3-[1-(3-Bromophenyl)-1-hydroxy-n-butyl]benzoic Acid t-Butyl Ester | 3-[1-(3-Bromophenyl)-1-hydroxy-n-butyl]benzoic Acid t-Butyl Ester is an impurity of Lumacaftor (V900700), which is used in the stabilization of the CFTR protein used in the treatment of cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C22H27BrO3, Molecular Weight: 419.35. US Biological Life Sciences. | Worldwide |
| 3-[1-(3-Bromophenyl)-1-hydroxy-n-butyl]benzoic Acid t-Butyl Ester-D9 | 3-[1-(3-Bromophenyl)-1-hydroxy-n-butyl]benzoic Acid t-Butyl Ester-D9 is the deuterium labelled analogue of 3-[1-(3-Bromophenyl)-1-hydroxy-n-butyl]benzoic Acid t-Butyl Ester (B699930), which is an impurity of Lumacaftor (V900700), which is used in the stabilization of the CFTR protein used in the treatment of cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H18D9BrO3, Molecular Weight: 428.41. US Biological Life Sciences. | Worldwide |
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