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Lurbinectedin Lurbinectedin, also known as PM01183, is a synthetic tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogue with potential antineoplastic activity. DNA minor groove-binding agent PM01183 covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death. Synonyms: PM-01183; PM 01183; PM01183. Lurbinectedin. CAS No. 497871-47-3. Molecular formula: C41H44N4O10S. Mole weight: 784.881. BOC Sciences 8
Lurbinectedin Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC 50 values of 1.25 and 1.16 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PM01183; LY-01017. CAS No. 497871-47-3. Pack Sizes: 100 μg; 1 mg; 2 mg; 5 mg. Product ID: HY-16293. MedChemExpress MCE

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