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| Product | Description | |
|---|---|---|
| LY 294002 | Cas No. 154447-36-6. |  |
| LY 294002, 4?-NH? - CAS 942289-87-4 | A cell-permeable LY 294002 4'-amino derivative with enhanced potency against p110?/?/?/?. Group: Fluorescence/luminescence spectroscopy. |  |
| LY 294002 - CAS 154447-36-6 | LY294002, CAS 154447-36-6, is a cell-permeable, potent, reversible, and specific inhibitor of PI 3-kinase ((IC?? = 1.4 μM). Acts on the ATP-binding site. Group: Fluorescence/luminescence spectroscopy. | |
| LY 294002 hydrochloride | LY 294002 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 934389-88-5. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| LY 294002 hydrochloride | LY 294002 hydrochloride is a PI 3-kinase inhibitor with IC50 values of 0.31μM for PI 3-Kβ, 0.73μM for PI 3-Kα, 1.06μM for PI 3-Kδ and 6.60μM for PI 3-K&gamma. It can inhibit proliferation and induce apoptosis in human colon cancer cells. Synonyms: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride. Grades: ≥99% by HPLC. CAS No. 934389-88-5. Molecular formula: C19H17NO3.HCl. Mole weight: 343.81. | |
| InSolution LY 294002 - CAS 154447-36-6 | LY 294002, CAS 154447-36-6, is a 10 mM solution of LY 294002 (Cat. No. 440202) in DMSO. A cell-permeable, potent, reversible and specific inhibitor of PI 3-kinase (IC50 = 1.4 μM). Group: Fluorescence/luminescence spectroscopy. | |
| LY294002 | LY294002 is a potent inhibitor of phosphoinositide PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively. Synonyms: LY294002; LY-294002; LY 294002; 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one; 2-morpholino-8-phenyl-4H-chromen-4-one. Grades: >98%. CAS No. 154447-36-6. Molecular formula: C19H17NO3. Mole weight: 307.349. | |
| 3-Methyladenine | A widely used cell-permeable autophagic sequestration blocker that effectly protects cerebellar granule cells from apoptosis following serum/potassium deprivation. Although a known class III PI3K inhibitor (IC50=4.5mM in cell-free enzymatic assays), 3-MA exhibits quite distinct pharmacological properties from those of two other PI3K inhibitors, LY 294002 and Wortmannin.Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker that protects cerebellar granule cells from apoptosis following serum/potassium deprivation. Group: Biochemicals. Alternative Names: 3-Methyl-3H-purin-6-amine; 3-Methyl-6-aminopurine; 3-Methyladenine; 6-Amino-3-methylpurine; N3-Methyladenine; NSC 66389. Grades: Highly Purified. CAS No. 5142-23-4. Pack Sizes: 50mg, 100mg, 250mg. Molecular Formula: C6H7N5 0.1H2O, Molecular Weight: 150.95. US Biological Life Sciences. | Worldwide |
| LY 303511 - CAS 154447-38-8 | A cell-permeable negative control for the PI 3-kinase inhibitor LY 294002. Group: Fluorescence/luminescence spectroscopy. | |
| PI 828 | PI 828 is a cell permeable 4'-amino derivative which inhibits the p110α, p110β, p110δ, and p110γ subunits of PI 3-kinase. PI-828 is a potent inhibitor of phosphatidylinositol 3-kinase (PI3K; IC50s = 9.8, 183, 227, and 1,967 nM for p110β, p110α, p110δ, and p110γ, respectively) that displays higher potency than LY 294002. Synonyms: LY294002,4'-NH2; PI-828; PI 828; PI828. 2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one. Grades: ≥99% by HPLC. CAS No. 942289-87-4. Molecular formula: C19H18N2O3. Mole weight: 322.36. | |
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