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| Product | Description | |
|---|---|---|
| LY 344864 hydrochloride | LY 344864 hydrochloride is a 5-HT1F receptor agonist with EC50 value of 3 nM. Synonyms: LY 344864 hydrochloride; LY344864 hydrochloride; LY-344864 hydrochloride; N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1217756-94-9. Molecular formula: C21H22N3OF.HCl. Mole weight: 387.88. |  |
| LY 344864 Hydrochloride (5-HT1F Serotonin Receptor Agonist, LY 344864, LY344864, LY-344864) | A selective, brain penetrant, full agonist for the 5-HT1F receptor (pKi = 8.2). It possesses little affinity for the 56 other serotonergic and non-serotonergic neuronal binding sites examined. When examined for its ability to inhibit forskolin-induced cyclic AMP accumulation in cells stably transfected with human 5-HT1F receptors, LY344864 was shown to be a full agonist producing an effect similar in magnitude to serotonin itself. Suitable for both in vitro and in vivo applications and its effects are often reversed with the 5-HT1B/1D antagonist GR 127935. Group: Biochemicals. Grades: Highly Purified. CAS No. 186544-26-3. Pack Sizes: 10mg. Molecular Formula: C??H??FN?O·HCl. US Biological Life Sciences. |  Worldwide |
| LY 344864 | LY 344864 is a brain penetrant, full agonist that specifically targets 5-HT1F receptor (pKi = 8.2) with > 80-fold selectivity over other serotonin receptors (Ki values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μM for SR-1F, SR-1A, SR-1B. Synonyms: N-[(6R)-6-(dimethylamino)-6,7,8,9-tetrahydro-5H-carbazol-3-yl]-4-fluorobenzamide;hydrochlorideLY-344864; LY344864; LY 344864; LY-344864 HCl; LY-344864 hydrochloride. Grades: >99 %. CAS No. 186544-26-3. Molecular formula: C21H22FN3O. Mole weight: 351.42. | |
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