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LY2409881 LY2409881 is a novel selective inhibitor of IKK2. It inhibited constitutively activated NF-κB, and caused concentration- and time-dependent growth inhibition and apoptosis in lymphoma cells. It suppressed the activity of the NF-κB subunit p65 in lymphoma cells treated by the HDAC inhibitor romidepsin, underlying a potential mechanism of the marked synergy observed of these two drugs. Synonyms: LY2409881; LY 2409881; LY-2409881. Grades: >98%. CAS No. 946518-61-2. Molecular formula: C24H29ClN6OS. Mole weight: 485.04. BOC Sciences 10
LY2409881 Trihydrochloride LY2409881 is a potent and selective IKK2 inhibitor with IC50 of 30 nM, >10-fold selectivity over IKK1 and other common kinases. Synonyms: LY2409881; LY 2409881; LY-2409881. Grades: >98%. CAS No. 946518-60-1. Molecular formula: C24H32Cl4N6OS. Mole weight: 594.43. BOC Sciences 10

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