Lyase Suppliers USA
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Product | Description | |
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BMS 303141 (ATP Citrate Lyase Inhibitor, Orally Bioavailable, 3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide) Quick inquiry Where to buy Suppliers range | ATP citrate lyase (ACL) inhibitor (IC50 = 0.13um for human recombinant ACL); blocks lipid synthesis (IC50 = 8um in HepG2 cells). Displays no cytotoxicity up to a concentration of 50um. Lowers plasma glucose and triglycerides in a mouse model of hyperlipidemia. Orally bioavailable. Group: Biochemicals. Grades: Highly Purified. CAS No. 943962-47-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
(16α,17α)-Epoxy 16,17-Dihydroabiraterone Quick inquiry Where to buy Suppliers range | (16α,17α)-Epoxy 16,17-Dihydroabiraterone is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H31NO2. US Biological Life Sciences. | Worldwide |
16-Bromo-6 β-methoxy-3,5-cycloandrost-16-en-17-yl]-pyridine Quick inquiry Where to buy Suppliers range | 16-Bromo-6 β-methoxy-3,5-cycloandrost-16-en-17-yl]-pyridine is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C25H32BrNO. US Biological Life Sciences. | Worldwide |
16-Dehydro-17-pyridinyl-3 β -[ (t-Butyl) dimethylsiloxy]androst-5-ene-7-one Quick inquiry Where to buy Suppliers range | 16-Dehydro-17-pyridinyl-3 β -[ (t-Butyl) dimethylsiloxy]androst-5-ene-7-one is an intermediate in synthesizing 7-Ketoabiraterone Acetate (K170980), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 250mg. Molecular Formula: C30H43NO2Si. US Biological Life Sciences. | Worldwide |
16-Dehydro-3 β -[ (t-Butyl) dimethylsiloxy]androst-5-ene-7-one Trifluoromethane sulfonate Quick inquiry Where to buy Suppliers range | 16-Dehydro-3 β -[ (t-Butyl) dimethylsiloxy]androst-5-ene-7-one Trifluoromethane sulfonate is an intermediate in synthesizing 7-Ketoabiraterone Acetate (K170980), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg. Molecular Formula: C26H39F3O5SSi. US Biological Life Sciences. | Worldwide |
17-(3-Pyridinyl)-androsta-4,16-dien-3-one Quick inquiry Where to buy Suppliers range | 17-(3-Pyridinyl)-androsta-4,16-dien-3-one is a possible steroidal inhibitor of human cytochrome P 45017α-hydroxylase-C17,20-lyase. Group: Biochemicals. Grades: Highly Purified. CAS No. 154229-21-7. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C24H29NO, Molecular Weight: 347.49. US Biological Life Sciences. | Worldwide |
17-(3-Pyridinyl)-androsta-4,16-dien-3-one-d4 Quick inquiry Where to buy Suppliers range | 17-(3-Pyridinyl)-androsta-4,16-dien-3-one-d4 is labelled 17-(3-Pyridinyl)-androsta-4,16-dien-3-one (P991885) which is a possible steroidal inhibitor of human cytochrome P 45017α-hydroxylase-C17,20-lyase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C24H25D4NO, Molecular Weight: 351.52. US Biological Life Sciences. | Worldwide |
1-Amino-1-deoxy-D-fructose Acetate Quick inquiry Where to buy Suppliers range | 1-Amino-1-deoxy-D-fructose Acetate is an intermediate in the synthesis of inhibitors of sphinogosine-1-phosphate (S1P) lyase for treatment of autoimmune disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 6333-49-9. Pack Sizes: 50mg, 250mg. Molecular Formula: C8H17NO7. US Biological Life Sciences. | Worldwide |
1-[Bis (phenylmethyl)amino]-1-deoxy-D-fructose Quick inquiry Where to buy Suppliers range | 1-[Bis (phenylmethyl)amino]-1-deoxy-D-fructose is an intermediate in the synthesis of inhibitors of sphinogosine-1-phosphate (S1P) lyase for treatment of autoimmune disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 69712-22-7. Pack Sizes: 50mg, 250mg. Molecular Formula: C20H25NO5. US Biological Life Sciences. | Worldwide |
1-Trityl-1H-imidazole-5-carboxaldehyde Quick inquiry Where to buy Suppliers range | 1-Trityl-1H-imidazole-5-carboxaldehyde is derived from 5-Imidazolecarboxalde hyde (I350220), which is a 4-formyl derivative of imidazole used in the preparation of C17,20-lyase inhibitor for the treatemnet of androgen-dependent prostate cancer. 4-Imidazolecarboxalde hyde is also used in the synthesis of other biologically active compounds such as antimalarial drugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 172498-90-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C23H18N2O, Molecular Weight: 338.4. US Biological Life Sciences. | Worldwide |
2,5-Norbornadiene Quick inquiry Where to buy Suppliers range | 2,5-Norbornadiene shows anti-ethylene effects on plants and inhibits polyphenol oxidase, peroxidase and phenylalanine ammonia lyase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 121-46-0. Pack Sizes: 5ml, 10ml. Molecular Formula: C7H8, Molecular Weight: 92.14. US Biological Life Sciences. | Worldwide |
2-Acetyl-4-tetrahydroxybutyl imidazole Quick inquiry Where to buy Suppliers range | 2-Acetyl-4-tetrahydroxybutyl imidazole is an inhibitor of sphingosine-1-phosphate lyase and acts as an immunosuppressant. Uses: Immunosuppressive agents. Synonyms: 2-Athbi; THI; (1R,2S,3R)-2-acetyltetrahydroxybutylimidazole; 2-acetyl-4(5)-tetrahydroxybutyl imidazole. Grades: >99%. CAS No. 94944-70-4. Molecular formula: C9H14N2O5. Mole weight: 230.22. | |
2-Bromopropanedioic Acid Quick inquiry Where to buy Suppliers range | 2-Bromopropanedioic Acid is an analog of the competitive inhibitor, malonate. Inhibitory activity towards Isocitrate lyase. Group: Biochemicals. Alternative Names: Bromomalonic Acid; Monobromomalonic Acid. Grades: Highly Purified. CAS No. 600-31-7. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
2-Ethoxy-2-propenenitrile Quick inquiry Where to buy Suppliers range | 2-Ethoxy-2-propenenitrile is used in the synthesis of a minor constituent of Caramel Color III, 2-Acetyl-4 (5) - (1R, 2S, 3R, 4-tetrahydroxybutyl) imidazole, which lowers circulating lumyocytes count when fed to rats. Also, it is an intermediate used in the synthesis of (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole (A188490), which inhibits sphinogosine-1-phosphate (S1P) lyase for treatment of autoimmune disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 19479-65-3. Pack Sizes: 25mg, 50mg. Molecular Formula: C5H7NO, Molecular Weight: 97.12. US Biological Life Sciences. | Worldwide |
2-Methylheptanal-d3 Quick inquiry Where to buy Suppliers range | 2-Methylheptanal-d3 is the isotope labelled analog of 2-Methylheptanal (M311840); a useful reagent in hydroxynitrile lyase-catalyzed enzymic nitroaldol (Henry) reactions. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C8H13D3O, Molecular Weight: 131.229999999999. US Biological Life Sciences. | Worldwide |
3,5-cyclo-Abiraterone Quick inquiry Where to buy Suppliers range | 3,5-cyclo-Abiraterone is derived from Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H31NO. US Biological Life Sciences. | Worldwide |
4-Imidazolecarboxalde hyde Quick inquiry Where to buy Suppliers range | 4-Imidazolecarboxalde hyde is a 4-formyl derivative of imidazole used in the preparation of C17,20-lyase inhibitor for the treatemnet of androgen-dependent prostate cancer. 4-Imidazolecarboxalde hyde is also used in the synthesis of other biologically active compounds such as antimalarial drugs. Group: Biochemicals. Alternative Names: 1H-Imidazole-5-carboxaldehyde; 1H-Imidazole-4-carboxaldehyde; Imidazole-4(or 5)-carboxaldehyde; Imidazole-4-carboxaldehyde (8CI); 1H-Imidazol-4-carboxaldehyde; 1H-Imidazol-4-ylcarboxaldehyde; 1H-Imidazol-5-carboxaldehyde; 1H-Imidazole-4-carboxaldehyde; 3H-Imidazole-4-carboxaldehyde; 4 (5) -Imidazolecarboxalde hyde; 4-Formylimidazole; 5-Imidazolecarboxalde hyde; NSC 400521. Grades: Highly Purified. CAS No. 3034-50-2. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
5-Imidazolecarboxalde hyde-15N2 Quick inquiry Where to buy Suppliers range | 4-Imidazolecarboxalde hyde is used in the preparation of C17,20-lyase inhibitor for the treatemnet of androgen-dependent prostate cancer. 4-Imidazolecarboxalde hyde is also used in the synthesis of other biologically active compounds such as antimalarial drugs. Group: Biochemicals. Alternative Names: 1H-Imidazole-5-carboxaldehyde-15N2; 1H-Imidazole-4-carboxaldehyde-15N2; Imidazole-4(or 5)-carboxaldehyde-15N2; Imidazole-4-carboxaldehyde-15N2; 1H-Imidazol-4-carboxaldehyde-15N2; 1H-Imidazol-4-ylcarboxaldehyde-15N2; 1H-Imidazol-5-carboxaldehyde-15N2; 1H-Imidazole-4-carboxaldehyde-15N2; 3H-Imidazole-4-carboxaldehyde-15N2; 4 (5) -Imidazolecarboxalde hyde-15N2; 4-Formylimidazole-15N2; 5-Imidazolecarboxalde hyde-15N2; NSC 400521-15N2. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
7-Azido-4-methylcoumarin (AzMC) Quick inquiry Where to buy Suppliers range | Highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4- methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex=365nm and lambdaem=450nm. Photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). Probe to monitor the enzymatic production of H2S in vitro and to visualize H2S in living cells. Tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)). Tool to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. Suitable for high-throughput screening. Use of this product with DTT, TCEP and/or biological thiols at concentrations of >25mM should be avoided for maximum efficiency. Group: Biochemicals. Grades: Highly Purified. CAS No. 95633-27-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
Abiaterone-5,6-epoxide Quick inquiry Where to buy Suppliers range | Abiaterone-5,6-Epoxide is an impurity of Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C24H33NO2, Molecular Weight: 367.52. US Biological Life Sciences. | Worldwide |
Abiraterone Quick inquiry Where to buy Suppliers range | Abiraterone is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. Group: Biochemicals. Alternative Names: 17-(3-Pyridyl)androsta-5,16-dien-3 β-ol;Androsta-5,16-dien-3-ol. Grades: Reagent Grade. CAS No. 154229-19-3. Pack Sizes: 100mg, 250mg, 1g, 5g. Molecular Formula:?C??H??NO , CAS No:?154229-19-3. US Biological Life Sciences. | Worldwide |
Abiraterone Acetate 99+% Quick inquiry Where to buy Suppliers range | Abiraterone acetate is a novel steroidal inhibitor of human Cytochrome P450 (17α-Hydroxylase-C17,20-lyase) and a potential agent for the treatment of prostatic cancer. Group: Biochemicals. Alternative Names: 17-(3-Pyridinyl)-androsta-5,16-dien-3-beta-ol acetate. Grades: Reagent Grade. CAS No. 154229-18-2. Pack Sizes: 1g. Molecular Formula: C??H??NO?, Molecular Weight: 391.55. US Biological Life Sciences. | Worldwide |
Abiraterone-d4 Quick inquiry Where to buy Suppliers range | Labeled Abiraterone. A steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. Group: Biochemicals. Alternative Names: (3 β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol-d4; CB 7598-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Abiraterone Isopropyl Ether Quick inquiry Where to buy Suppliers range | Abiraterone Isopropyl Ether is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C27H37NO, Molecular Weight: 391.59. US Biological Life Sciences. | Worldwide |
Abiraterone Related Compound 7 Quick inquiry Where to buy Suppliers range | An impurity of Abiraterone , a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor. Synonyms: Abiraterone Impurity 7. Grades: > 95%. Molecular formula: C47H61NO4. Mole weight: 704.01. | |
Adenylosuccinic acid Quick inquiry Where to buy Suppliers range | Adenylosuccinic acid is a vital compound in the biomedical industry used primarily in the research of inherited metabolic disorders, such as adenylosuccinate lyase deficiency. Synonyms: Adenylosuccinic acid; 19046-78-7; Aspartyl adenylate; adenylosuccinate; Succinyl AMP; X1B4ZJ0IIV; Succinyladenosine 5'-monophosphate; N6-(1,2-dicarboxyethyl)-AMP; L-Aspartic acid, N-[9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purin-6-yl]-; 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID; Succinyladenosine monophosphoric acid; L-Aspartic acid, N-(9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purin-6-yl)-; N (6)- (1, 2-dicarboxyethyl)AMP; (2S)-2-[ (9-{ (2R, 3R, 4S, 5R)-3, 4-dihydroxy-5-[ (phosphonooxy)methyl]tetrahydrofuran-2-yl}-9H-purin-6-yl)amino]butanedioic acid (non-preferred name). Grades: 95%. CAS No. 19046-78-7. Molecular formula: C14H18N5O11P. Mole weight: 463.29. | |
Aminoethoxyvinyl glycine Hydrochloride (ABG 3168) Quick inquiry Where to buy Suppliers range | Ethylene, an important plant regulator, is synthesized from S-adenosyl-L-methionine by the sequential action of 1-amino-cyclopropane-carboxylate (ACC) synthases (ACSs) and ACC oxidases (ACOs). Aminoethoxyvinyl glycine is an inhibitor of ethylene biosynthesis that, at 1uM, blocks the activity of both ACSs and ACOs.1 Through this action, it reduces ethylene-mediated changes in plant growth and development.2,3,4 Aminoethoxyvinyl glycine also inhibits cystathionine γ-lyase (Ki = 10.5uM) with slow- and tight-binding characteristics.5. Group: Biochemicals. Alternative Names: (2S,3E)-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Monohydrochloride; [S-(E)]-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Monohydrochloride; (S)-trans-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Hydrochloride; ABG 3168 Hydrochloride; L-2-Amino-4-(2'-aminoethoxy)-trans-3-butenoic Acid Hydrochloride; ReTain Hydrochloride; ReTain (plant growth regulator) Hydrochloride. Grades: Highly Purified. CAS No. 55720-26-8. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C?H??ClN?O?, Molecular Weight: 196.63. US Biological Life Sciences. | Worldwide |
Antimycin A1 Quick inquiry Where to buy Suppliers range | Antimycin A is a macrolide antibiotic produced by Streptomyces kitasawaensis, Str. griseus and Str. antibioticus. Antimycin A1 can inhibit atp-citrate lyase activity. Synonyms: dihydrosamidin. Grades: >98% by HPLC. CAS No. 642-15-9. Molecular formula: C28H40N2O9. Mole weight: 548.62. | |
Antimycin A2 Quick inquiry Where to buy Suppliers range | Antimycin A is a macrolide antibiotic produced by Streptomyces kitasawaensis, Str. griseus and Str. antibioticus. Antimycin A2 can inhibit atp-citrate lyase activity. Synonyms: 3-(3-Formamidosalicylamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl butyrate. Grades: 90%. CAS No. 27220-57-1. Molecular formula: C27H38N2O9. Mole weight: 534.60. | |
Antimycin A3 Quick inquiry Where to buy Suppliers range | Antimycin A is a macrolide antibiotic produced by Streptomyces kitasawaensis, Str. griseus and Str. antibioticus. Antimycin A3 can inhibit atp-citrate lyase activity. Synonyms: Blastomycin. Grades: >98% by HPLC. CAS No. 522-70-3. Molecular formula: C26H36N2O9. Mole weight: 520.57. | |
Antimycin A4 Quick inquiry Where to buy Suppliers range | Antimycin A is a macrolide antibiotic produced by Streptomyces kitasawaensis, Str. griseus and Str. antibioticus. Antimycin A4 can inhibit atp-citrate lyase activity. Synonyms: 8-Butyl-3-(3-formamido-2-hydroxybenzamido)-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl butyrate. Grades: >98% by HPLC. CAS No. 27220-59-3. Molecular formula: C25H34N2O9. Mole weight: 506.54. | |
BMS-351 Quick inquiry Where to buy Suppliers range | BMS-351 is a selective and nonsteroidal CYP17A1 lyase inhibitor with good selectivity over steroidogenic CYPs 21A2 and 11B1. BMS-351 has become a preclinical candidate to treat Castration-resistant prostate cancer (CRPC) and is likely to minimize the side effects of current therapies because of its exceptional selectivity. Uses: Castration-resistant prostate cancer. Synonyms: BMS-351; BMS 351; BMS351; 4-(4-methylpyridin-3-yl)-1-(2,2,2-trifluoroethyl)-1H-benzo[d]imidazole. Grades: 98%. CAS No. 1370001-71-0. Molecular formula: C15H12F3N3. Mole weight: 291.28. | |
DL-Propargyl glycine hydrochloride Quick inquiry Where to buy Suppliers range | DL-Propargyl glycine (PAG) is an irreversible inhibitor of the H2S synthesizing enzyme cystathionine-γ-lyase (CSE). PAG blocks H2S synthesis activity in rat liver preparations with an IC50 value of 55 μM and abolishes the rise in plasma H2S in anaesthetized rats induced with hemorrhagic shock. Synonyms: PAG; 2-Aminopent-4-ynoic acid hydrochloride; AK323755; AK110719. Grades: ≥95%. CAS No. 16900-57-5. Molecular formula: C5H7NO2·HCl. Mole weight: 149.6. | |
DL-threo-2-methylisocitrate Quick inquiry Where to buy Suppliers range | DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1(ICL1). Synonyms: DL-threo-2-methylisocitrate; 71183-66-9; alpha-methylisocitric acid; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid; methylisocitrate; Methylisocitric acid; threo-Pentaric acid, 3-carboxy-2,3-dideoxy-4-C-methyl-; SCHEMBL1533821; CHEBI:15607; DTXSID301209270; LMFA01050444; AKOS030526883; DB04072; HY-16581; C04593; Q27098140; 3-carboxy-2,3-dideoxy-4-C-methyl-L-threo-pentaric acid; rel-(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylic acid; rel-(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylicacid. Grades: >98%. CAS No. 71183-66-9. Molecular formula: C14H20O14. Mole weight: 412.3. | |
Ec 4.1.1.18 type i Quick inquiry Where to buy Suppliers range | partially purified powder. Group: Heterocyclic Organic Compound. Alternative Names: L-LYSINE CARBOXY LYASE;L-LYSINE CARBOXY-LYASE TYPE I;L-LYSINE CARBOXY-LYASE TYPE III;L-LYSINE DECARBOXYLASE;L-LYSINE DECARBOXYLASE TYPE I;L-LYSINE DECARBOXYLASE TYPE III;EC 4.1.1.18;EC 4.1.1.18 TYPE I. CAS No. 9024-76-4. Mole weight: 0. | |
ETC-1002 Quick inquiry Where to buy Suppliers range | ETC-1002 is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule and is activator of hepatic AMP-activated protein kinase (AMPK). It also has potent inhibitory activity against hepatic ATP-citrate lyase. Synonyms: ESP-55016; ESP55016; ESP 55016; ETC-1002; ETC 1002; ETC1002; Bempedoate; Bempedoic acid. Grades: >98%. CAS No. 738606-46-7. Molecular formula: C19H36O5. Mole weight: 344.49. | |
Heparinase Quick inquiry Where to buy Suppliers range | Heparinase. Group: Heterocyclic Organic Compound. Alternative Names: HEPARIN LYASE I;HEPARINASE;HEPARINASE I;EC 4.2.2.7;Lyase, heparin;HeparinlyaseI, Heparinase;HeparinaseI from Flavobacterium heparinum,Heparin lyaseI, Heparinase;Neutralase. CAS No. 9025-39-2. Molecular formula: NULL. Mole weight: 0. | |
Heparinase I Quick inquiry Where to buy Suppliers range | This enzyme selectively cleaves highly sulfated polysaccharide chains containing 1-4 linkages between N-sulfated glucaoamine and 2-O-sulfated iduronic acid. It cleaves heparin sulfate but only to a limited extent in the sulfated zone. It also cleaves the antithrombin III pentasaccharide unit in the heparin molecule. Optimum pH 7.0-7.6. Stabilised with 0.2-0.4% BSA, 0.22 μm sterile filtered and dispensed into sterile tubes/vials. Synonyms: Native Flavobacterium Heparinum Heparinase I; EC 4.2.2.7; Heparinase I; Heparin Eliminase; Heparinase; Heparin Lyase; Heparinase I From Bacteroides Eggerthii, Recombinant. Grades: 95%. CAS No. 9025-39-2. Mole weight: 42.8 kDa. | |
Heparinase II from Flavobacterium heparinum Quick inquiry Where to buy Suppliers range | This enzyme cleaves most links in heparin and heparin sulfate. It is relatively non-specific for 1-4 links in sulfated polysaccharide chains between hexosamines and glucuronic acid plus iduronic acids, but does not fully depolymerise either. Optimum pH 7.0-7.6. Stabilised with 0.2-0.4% BSA, 0.22 μm sterile filtered and dispensed into sterile tubes/vials. Synonyms: Heparinase II; Heparin lyase II; EC 4.2.2.8. CAS No. 149371-12-0. Mole weight: 84.1 kDa. | |
Heparinase III Quick inquiry Where to buy Suppliers range | The enzyme cleaves 1-4 linkages between N-acetylated or N-sulphated glucosamine and glucuronic acid residues. It is only active towards heparan sulfate in the low sulphated zone and does not cleave heparin or low molecular weight heparins. Highly sulfated zones are resistant to it and activity towards iduronic acid is very low. Stabilised with 0.2-0.4% BSA, 0.22 μm sterile filtered and dispensed into sterile tubes/vials. Synonyms: Heparinase III from Flavobacterium heparinum; Heparin Lyase III; Heparitinase I; Heparan monosulfate lyase; Heparin sulfate eliminase; Heparin-sulfate lyase. CAS No. 37290-86-1. Mole weight: 70.8 kDa. | |
Hyaluronidase Quick inquiry Where to buy Suppliers range | lyophilized powder. Group: Heterocyclic Organic Compound. Alternative Names: EC 4.2.2.1;HYALURONATE LYASE; Hyaluronidase(fromtestes); hyaluronidasefromstreptomyceshyaluro-lyticus; Mucinase; Hyaluronidase Streptomyces hyalurolyticus;HYALURONATE LYASE FROM STREPTOMYCES*HYAL UROLYTICUS;HYALURONIDASE FROM STREPTOMYCES HYALURO- LYTICUS, ~0.1U/VIAL. CAS No. 9001-54-1. Molecular formula: n.a. Mole weight: 0. Safty Description: 22-24/25. | |
(-)-Hydroxycitric acid Quick inquiry Where to buy Suppliers range | (-)-Hydroxycitrate is a potent competitive inhibitor of ATP citrate lyase, which inhibits fatty acid synthesis, lipogenesis, food intake and induced weight loss. Synonyms: Garcinia acid. Grades: 95%. CAS No. 27750-10-3. Molecular formula: C6H8O8. Mole weight: 208.12. | |
Hydroxycitric acid Quick inquiry Where to buy Suppliers range | Hydroxycitric acid is a natural compound found in the fruits of Garcinia atroviridis. Hydroxycitric acid acts as an inhibitor of the enzyme ATP-citrate lyase. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Hydroxycitrate; (-)-Hydroxycitric acid; Hydroxycitricacid; 1,2-Dihydroxy-1,2,3-propanetricarboxylic acid. Grades: 60%. CAS No. 6205-14-7. Molecular formula: C6H8O8. Mole weight: 208.122. | |
Ilimaquinone Quick inquiry Where to buy Suppliers range | Cytoplasmic microtubule inhibitor. Cell permeable, antimicrobial, anti-inflammatory, antimitotic and cytotoxic compound. Induces a complete and reversible breakdown/disruption of Golgi membranes into smaller vesicular structures. Blocks the association of the ADP-ribosylation factor and beta-COP to the Golgi membrane. Blocks protein transport to the plasma membrane and inhibits gap junctional communication. HIV-1 inhibitor. Blocks the cytotoxicity of ricin and diphtheria toxin. S-Adenosylhomocysteinase hydrolase inhibitor and cellular methylations inhibitor. DNA polymerase beta lyase activity inhibitor. Anti-cancer compound. Source:Isolated from Anthelia sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 71678-03-0. Pack Sizes: 100ug. Molecular Formula: C22H30O4. US Biological Life Sciences. | Worldwide |
Itaconic acid Quick inquiry Where to buy Suppliers range | Inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth. Antimicrobial. Antibacterial. Inhibits the growth of bacteria expressing isocitrate lyase. Phosphofructokinase (PFKII) inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat. Might be involved in the regulation of metabolism. Group: Biochemicals. Alternative Names: 2-Methylenebutanedioic Acid; Methylenesuccinic Acid; 2-Methylenebutanedioic Acid; 2-Methylenesuccinic Acid; 2-Propene-1,2-dicarboxylic Acid; 4-Hydroxy-2-methylene-4-oxobutanoic Acid; Methylenebutanedioic Acid; NSC 3357; Propylenedicarboxylic Acid. Grades: Highly Purified. CAS No. 97-65-4. Pack Sizes: 1g, 5g. Molecular Formula: C?H?O?. US Biological Life Sciences. | Worldwide |
L-Cysteine Hydrochloride Quick inquiry Where to buy Suppliers range | L-cysteine hydrochloride is the salt form of L-cysteine, which acts as a histidine ammonia-lyase inhibitor. Protein supplement in health care products. Uses: Ingredient of health care products. Synonyms: (r)-cysteinehydrochloride; (R)-Cysteine-hydrochloride; 3-Mercaptoalanine hydrochloride; Cystein chloride; Cysteine chlorhydrate; Cysteine chlorohydrate; Cysteine, hydrochloride, L-; cysteinechlorhydrate. Grades: 98%. CAS No. 52-89-1. Molecular formula: C3H7NO2S.HCl. Mole weight: 157.61. | |
L-Propargylglycine Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptomyces sp. It can inactivate many vitamin B6-enzymes, such as Cystathionine γ-synthase, Methionone γ-lyase and L-alanine aminotransferase. Synonyms: (S)-2-Aminopent-4-ynoic acid; (S)-2-Amino-4-pentynoic acid; L-2-Propynylglycine; (S)-Propargylglycine; (S)-2-Propargylglycine; L-Pra-OH; L-Propargyl-Gly-OH; 4-Pentynoic acid, 2-amino-, (2S)-; (2S)-2-Amino-4-pentynoic acid; 4-Pentynoic acid, 2-amino-, (S)-; 4-Pentynoic acid, 2-amino-, L-; (2S)-2-Azaniumylpent-4-ynoate; (S)-α-Propargylglycine; L-2-Amino-4-pentynoic acid. Grades: ≥95%. CAS No. 23235-01-0. Molecular formula: C5H7NO2. Mole weight: 113.11. | |
MEDICA 16 Quick inquiry Where to buy Suppliers range | MEDICA 16 is a selective free fatty acid 1 receptor agonist. It is also an ATP citrate lyase inhibitor. MEDICA 16 shows hypolipidemic and antidiabetogenic effects in the rat. Synonyms: MEDICA 16; MEDICA16; MEDICA-16; 3,3,14,14-Tetramethylhexadecanedioic acid. Grades: ≥98% by HPLC. CAS No. 87272-20-6. Molecular formula: C20H38O4. Mole weight: 342.51. | |
N-Acetylneuraminic Acid Aldolase Quick inquiry Where to buy Suppliers range | N-Acetylneuraminic Acid Aldolase. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: EC 4.1.3.3;N-ACETYLNEURAMINIC ACID ALDOLASE;N-ACETYLNEURAMINIC ACID ALDORASE;N-ACETYLNEURAMINATE PYRUVATE LYASE;NEU5AC ALDOLASE;N-Acetylneuraminic Acid Aldolase from microorganisms;N-ACETYLNEURAMINIC ACID ALDOLASE, FROM MICROORGANISM;N-Acetylneuraminate Pyruvate Lyase, N-Acetylneuraminic Acid Lyase, NANA Aldolase, Sialic Aldolase. CAS No. 9027-60-5. Pack Sizes: 1 kg. Product ID: CDF4-0055. | |
Orteronel Quick inquiry Where to buy Suppliers range | Orterone (TAK-700) is an orally bioavailable non-steroidal androgen synthesis inhibitor of steroid 17alpha-monooxygenase (17,20 lyase) with potential antiandrogen activity. TAK-700 binds to and inhibits the steroid 17alpha-monooxygenase in both the testes and adrenal glands, thereby inhibiting androgen production. This may decrease androgen-dependent growth signaling and may inhibit cell proliferation of androgen-dependent tumor cells. The cytochrome P450 enzyme CYP17A1 (P450C17), localized to the endoplasmic reticulum (ER), exhibits both 17alpha-hydroxylase and 17,20-lyase activities, and plays a key role in the steroidogenic pathway that produces steroidal hormones, such as progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Synonyms: TAK-700; TAK 700; TAK700. Grades: >98%. CAS No. 566939-85-3. Molecular formula: C18H17N3O2. Mole weight: 307.353. | |
Radicicol Quick inquiry Where to buy Suppliers range | Antibiotic. Protein tyrosine kinase inhibitor. Has antifungal, antimalarial, antiangiogenic (in vivo), anti-inflammatory and antiviral activity. Cyclooxygenase-2 (COX-2) expression inhibitor without affecting COX-1 expression in LPS-stimulated macrophages. Induces the differentiation of HL-60 cells into macrophages. Potent HSP90 inhibitor. Anticancer compound. In vivo Rad/Raf interaction inhibitor. Inhibitor of AP-1-, NF-kappaB- and serum response factor (SRF)-mediated transcription. Suppresses expression of iNOS (NOS II). Non-competitive inhibitor of ATP citrate lyase. DNA topoisomerase VI and type II DNA topoisomerase inhibitor. Protects against LPS/IFN-gamma-induced neuronal cell death. Apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 12772-57-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C18H17ClO6. US Biological Life Sciences. | Worldwide |
Salicylanilide Quick inquiry Where to buy Suppliers range | Salicylanilide has a wide range of biological activities, including antiviral, anti-inflammatory, antibacterial and so on. It inhibits HIV virus by targeting HIV-1 integrase or reverse transcriptase. It inhibits mycobacterial isocitrate lyase (ICL) and has a significant antimycobacterial effect. It can be used as an antiseptic. Synonyms: 2-Hydroxybenzanilide; 2-(N-Phenylcarboxamido)phenol; 2-(Phenylaminocarbonyl)phenol; Ansadol; Aseptolan; Hyanilid; N-Phenyl-2-hydroxybenzamide; N-Phenylsalicylamide; NSC 14881; Salicylanilid; Salicylic acid anilide; Salifebrin; Salinide; Salinidol; Salnide; Shirlan; o-Hydroxybenzanilide. Grades: ≥95%. CAS No. 87-17-2. Molecular formula: C13H11NO2. Mole weight: 213.23. | |
SB 204990 Quick inquiry Where to buy Suppliers range | SB 204990 is a prodrug of SB 201076, which is an ATP citrate lyase (ACLY) inhibitor. SB 204990 inhibits cholesterol and fatty acid synthesis in a dose-dependent manner in HepG2 cells. SB 204990 was shown to decrease plasma levels of the lipoproteins VLDL, LDL, and HDL in dogs. Synonyms: SB-204990; SB 204990; SB204990; (3R,5S)-rel-5-[6-(2,4-Dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanacetic acid. Grades: ≥98% by HPLC. CAS No. 154566-12-8. Molecular formula: C18H22Cl2O5. Mole weight: 389.27. | |
SHIP 2a Quick inquiry Where to buy Suppliers range | SHIP 2a is a cystathione γ lyase (CSE) inhibitor (IC50 = 6.3 μM). SHIP 2a was demonstrated ability to suppress H2S production in mouse aorta homogenates and L-cysteine-induced relaxation of rat aortic rings ex vivo. Synonyms: (R)-2-Oxo-N-2-propyn-1-yl-4-thiazolidinecarboxamide. Grades: ≥98% by HPLC. Molecular formula: C7H8N2O2S. Mole weight: 184.22. | |
Sialic acid aldolase - crystalline Quick inquiry Where to buy Suppliers range | Sialic Acid Aldolase - Crystalline is an exquisitely filtered enzyme, finding profound involvement in the synthetic and catabolic processes of sialic acids, serving as pivotal constituents of glycoproteins and glycolipids. Synonyms: N-Acetylneuraminic acid aldolase; N-Acetylneuraminate lyase; Sialate lyase. | |
TAK-700 Quick inquiry Where to buy Suppliers range | TAK-700 (Orteronel) is a potent and highly selective human 17,20-lyase inhibitor with IC50 of 38 nM, exhibits >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). It completed two phase III clinical trials for metastatic, hormone-refractory prostate cancer but failed to extend overall survival rates, and development was voluntarily terminated as a result. Synonyms: TAK-700; TAK700; (S/R)-Orteronel; 6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide. Grades: >98%. CAS No. 426219-18-3. Molecular formula: C18H17N3O2. Mole weight: 307.35. | |
Traumatic Acid Quick inquiry Where to buy Suppliers range | Traumatic Acid, is the product of a biosynthetic pathway from a physiological role of alpha-ketol fatty acids in plant lipid hydroperoxide lyase metabolism. This compound is also used in would healing as it stimulates cell division to form a protective callus around the wound site. Group: Biochemicals. Grades: Highly Purified. CAS No. 6402-36-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C12H20O4, Molecular Weight: 228.28. US Biological Life Sciences. | Worldwide |
VT-464 Quick inquiry Where to buy Suppliers range | VT-464, also called as Seviteronel, is an oral, non-steroidal, lyase-selective CYP17 inhibitor to reach Phase II clinical trials in Breast cancer in USA (PO). in vitro: Approximately 10-fold more selective towards lyase than hydroxylase. Selective inhibit. Uses: Antineoplastic agents. Synonyms: (1S)-1-[6,7-bis(difluoromethoxy)naphthalen-2-yl]-2-methyl-1-(2H-triazol-4-yl)propan-1-ol; VT464; VT 464; VT-464; INO-464; INO 464; INO464;CHEMBL3264610; CS-3139; CS 3139; CS3139; HY-15996; UNII-8S5OIN36X4 component ZBRAJOQFSNYJMF-SFHVURJKSA-N; 1610537-15-9; 1H-1,2,3-Triazole-5-methanol, alpha-(6,7-bis(difluoromethoxy). CAS No. 1610537-15-9. Molecular formula: C18H17F4N3O3. Mole weight: 399.34. | |
VT-464 racemate Quick inquiry Where to buy Suppliers range | The racemate form of VT-464, a non-steroidal compound, has been found to lead to the reduction of androgen through acting as a human CYP17 lyase inhibitor. IC50: 69 nM. Uses: The racemate form of vt-464 has been found to lead to the reduction of androgen through acting as a human cyp17 lyase inhibitor. Synonyms: VT-464 racemate; VT 464 racemate; VT464 racemate; VT-464; CHEMBL3264610; CS-3139; CS 3139; CS3139; UNII-8S5OIN36X4 component ZBRAJOQFSNYJMF-SFHVURJKSA-N. Grades: 98%. CAS No. 1375603-36-3. Molecular formula: C18H17F4N3O3. Mole weight: 399.34. | |
VT-464 R enantiomer Quick inquiry Where to buy Suppliers range | The R-enantiomer form of VT-464, a non-steroidal compound, has been found to lead to the reduction of androgen through acting as a human CYP17 lyase inhibitor. Uses: The r-enantiomer form of vt-464 has been found to lead to the reduction of androgen through acting as a human cyp17 lyase inhibitor. Synonyms: VT-464 (R enantiomer); VT 464 R enantiomer; VT464 R enantiomer; CS-3140; CS 3140; CS3140; UNII-8S5OIN36X4 component ZBRAJOQFSNYJMF-GOSISDBHSA-N. Grades: 98%. CAS No. 1375603-38-5. Molecular formula: C18H17F4N3O3. Mole weight: 399.34. |