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An amide analog of Trichostatin A that potently Inhibits histone deacetylases (IC50 = 40 nM for rat liver HDAC and IC50 = 100 nM for maize HDAC). Induces differentiation and inhibits proliferation (~2uM) of murine erythroleukemia cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 251456-60-7. Pack Sizes: 1mg. US Biological Life Sciences.
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M344
M344 (D 237) is an inhibitor of histone deacetylase ( IC 50 =100 nM) and an inducer of terminal cell fifferentiation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D 237; MS 344. CAS No. 251456-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13506.
M344
M344 is a potent HDAC inhibitor, which can also induce expression of the pro-apoptotic genes, Puma and Bax, together with the morphological features of apoptosis, in MCF-7 cells. Synonyms: M 344; M-344; Histone Deacetylase Inhibitor III. Grades: >98%. CAS No. 251456-60-7. Molecular formula: C16H25N3O3. Mole weight: 307.39.
11a-Chloro-12-oxo Minocycline
11a-Chloro-12-oxo Minocycline is an intermediate in synthesizing Δ5a-11-Hydroxy-12-oxo Minocycline Disodium Salt (H948925), an impurity of Minocycline (M344800). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H26ClN3O7. US Biological Life Sciences.
Worldwide
1-?(4-?Pyridinyl)?-2-butanone
1-(4-Pyridinyl)-2-butanone is an intermediate in the synthesis of Milrinone (M344680) and Amrinone (A635000) analogues used as an cardiotonic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 6304-20-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H11NO. US Biological Life Sciences.
1-(Dimethylamino)-2-(4-pyridinyl)-1-penten-3-one is an intermediate in the synthesis of Milrinone (M344680) and Amrinone (A635000) analogues used as an cardiotonic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 78504-62-8. Pack Sizes: 50mg, 250mg. Molecular Formula: C12H16N2O. US Biological Life Sciences.
Worldwide
(1R, 1'R, 2S, 2'S) -2, 2'- ( ( (2-Aminopropane -1, 3-diyl) bis (oxy) ) bis ( methyl ene ) ) bis (phenylcyclopropane carboxamide)
(1R, 1'R, 2S, 2'S) -2, 2'- ( ( (2-Aminopropane -1, 3-diyl) bis (oxy) ) bis ( methyl ene ) ) bis (phenylcyclopropane carboxamide) is an impurity of the drug Milnacipria (M344600), which is an antidepressnant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C25H31N3O4, Molecular Weight: 437.53. US Biological Life Sciences.
(1R, 2R) -2- (Hydroxy methyl ) -1-phenylcyclopropane carboxylic Acid is an impurity in the synthesis of Milnacipran (M344600). Milnacipran is an antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C11H12O3, Molecular Weight: 192.21. US Biological Life Sciences.
(1R, 2R) -rel-2- [ (1, 3-Dihydro-1, 3-dioxo-2H-isoindol-2-yl) methyl ] -N, N-diethyl-1-phenyl-cyclopropane carboxamide is an intermediate in synthesizing rac,trans-Milnacipran Hydrochloride (M344625), which is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 907205-34-9. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C22H22N2O3. US Biological Life Sciences.
(1R, 2R) -rel-N, N-Diethyl-2- (hydroxy methyl ) -1-phenyl-cyclopropane carboxamide is an intermediate in synthesizing rac,trans-Milnacipran Hydrochloride (M344625), which is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1797131-72-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C15H21NO2. US Biological Life Sciences.
(1R, 2S) -rel-N, N-Diethyl-2- [ [ [ (4- methyl phenyl) sulfonyl] oxy] methyl ] -1-phenyl-cyclopropane carboxamide is an intermediate in synthesizing rac,trans-Milnacipran Hydrochloride (M344625), which is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 923037-67-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C22H27NO4S. US Biological Life Sciences.
(1S, 2S) -2- (Acetoxy methyl ) -1-phenylcyclopropane carboxylic Acid is an intermediate in synthesizing rac,trans-Milnacipran Hydrochloride (M344625), which is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C13H14O4. US Biological Life Sciences.
( (1S, 2S) -2- (Diethylcarbamoyl) -2-phenylcyclopropyl) methyl Acetate is an intermediate in synthesizing rac,trans-Milnacipran Hydrochloride (M344625), which is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C17H23NO3. US Biological Life Sciences.
(1S, 2S) -2- (Hydroxy methyl ) -1-phenylcyclopropane carboxylic Acid is an impurity in the synthesis of Milnacipran (M344600). Milnacipran is an antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C11H12O3, Molecular Weight: 192.21. US Biological Life Sciences.
Worldwide
2-(2,3-Dimethoxyphenyl)propan-2-ol
2-(2,3-Dimethoxyphenyl)propan-2-ol is an intermediate of Miltirone (M344500), an active component in Salvia miltiorrhiza that has been shown to inhibit the increase in the abundance of the mRNA for the α4 subunit of the GABAA receptor induced by ethanol withdrawal in cultured hippocampal neurons. A potential phytotherapeutic agent in the treatment of alcohol dependence. Group: Biochemicals. Grades: Highly Purified. CAS No. 153390-68-2. Pack Sizes: 100mg, 500mg. Molecular Formula: C11H16O3. US Biological Life Sciences.
Worldwide
2,3,4,6-Tetra-O-benzyl-1-L-ido-deoxynojirimycin
2,3,4,6-Tetra-O-benzyl-1-L-ido-deoxynojirimycin is an intermediate in the synthesis of N-substituted iminosugar derivative, miglitol (M344200). Group: Biochemicals. Grades: Highly Purified. CAS No. 76738-52-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C34H37NO4. US Biological Life Sciences.
2- (Hydroxy methyl ) -1-phenylcyclopropane carbonitrile is the degradation product of Milnacipran (M344600), which is a selective norepinephrine and serotonin reuptake inhibitor approved for management of fibromyalgia; antidepressant. Group: Biochemicals. Grades: Highly Purified. CAS No. 60788-55-8. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H11NO, Molecular Weight: 173.21. US Biological Life Sciences.
2'-Methyl-6'-oxo-1',6'-dihydro-[2,3'-bipyridine]-5'-carbonitrile is an impurity of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic. Group: Biochemicals. Grades: Highly Purified. CAS No. 106637-42-7. Pack Sizes: 500mg, 5g. Molecular Formula: C12H9N3O, Molecular Weight: 211.22. US Biological Life Sciences.
(2S, 3R, 4R, 5S)-3, 4, 5-Tris (phenylmethoxy)-2-[ (phenylmethoxy)methyl]-1- (2-propen-1-yl)-piperidine is an intermediate in the synthesis of N-substituted iminosugar derivative, miglitol (M344200). Group: Biochemicals. Grades: Highly Purified. CAS No. 1203659-55-5. Pack Sizes: 5mg, 25mg. Molecular Formula: C37H41NO4. US Biological Life Sciences.
(2S, 3R, 4R, 5S)-3, 4, 5-Tris (phenylmethoxy)-2-[ (phenylmethoxy)methyl]-1-piperidineethanol is an intermediate in the synthesis of N-substituted iminosugar derivative, miglitol (M344200). Group: Biochemicals. Grades: Highly Purified. CAS No. 1445783-86-7. Pack Sizes: 1mg. Molecular Formula: C36H41NO5. US Biological Life Sciences.
Worldwide
3-Isopropylcatechol
3-Isopropylcatechol is an intermediate formed in the synthesis of Miltirone (M344500), an active component in Salvia miltiorrhiza that has been shown to inhibit the increase in the abundance of the mRNA for the α4 subunit of the GABAA receptor induced by ethanol withdrawal in cultured hippocampal neurons. A potential phytotherapeutic agent in the treatment of alcohol dependence. Group: Biochemicals. Grades: Highly Purified. CAS No. 2138-48-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C9H12O2. US Biological Life Sciences.
Worldwide
3-Isopropylveratrole
3-Isopropylveratrole is an intermediate formed in the synthesis of Miltirone (M344500), an active component in Salvia miltiorrhiza that has been shown to inhibit the increase in the abundance of the mRNA for the α4 subunit of the GABAA receptor induced by ethanol withdrawal in cultured hippocampal neurons. A potential phytotherapeutic agent in the treatment of alcohol dependence. Group: Biochemicals. Grades: Highly Purified. CAS No. 71720-27-9. Pack Sizes: 25mg, 100mg. Molecular Formula: C11H16O2. US Biological Life Sciences.
Worldwide
9-Hydroxyminocycline
9-Hydroxyminocycline is a metabolite of the tetracycline antibiotic Minocycline (M344800, HCl) found in the blood and urine of humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 81902-32-1. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C23H27N3O8, Molecular Weight: 473.48. US Biological Life Sciences.
Worldwide
Vorinostat
Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM. Uses: Antineoplastic agents; histone deacetylase inhibitors. Synonyms: MK-0683, MK 0683, MK0683, SAHA, M344, CCRIS 8456, HSDB 7930, Vorinostat, suberoylanilide hydroxamic acid, Zolinza. Grades: >98%. CAS No. 149647-78-9. Molecular formula: C14H20N2O3. Mole weight: 264.3.
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