Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| M8 B hydrochloride | M8 B hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 883976-12-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| M8 B hydrochloride | M8 B hydrochloride is a selective and potent channel blocker of transient receptor potential melastatin 8 (TRPM8). It blocks cold-induced and icilin or methol-induced activation of rat, human, and murine TRPM8 channels. It displays no effect at other TRP channels with IC50 value of > 20 mM. It decreases deep body temperature in wild-type mice and rats but has no effect on body temperature in TRPM8 KO mice. It may be used to induce therapeutic hypothermia, which is an effective treatment in cardiac arrest. Synonyms: N-(2-Aminoethyl)-N-(4-(benzyloxy)-3-methoxybenzyl)thiophene-2-carboxamide hydrochloride; N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride; N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide, monohydrochloride. Grades: ≥99% by HPLC. CAS No. 883976-12-3. Molecular formula: C22H25N2O3SCl. Mole weight: 432.96. |  |
| M8-B hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
Our database is helping our users find suppliers everyday.
