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| Product | Description | |
|---|---|---|
| MAK683 | MAK683 is an embryonic ectoderm development ( EED ) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC 50 s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1951408-58-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103663. |  |
| MAK683-CH2CH2COOH hydrochloride | MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 (HY-130614) and PROTAC EED degrader-2 (HY-130615)[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130815A. | |
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