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Margatoxin Margatoxin (MgTx) is a component of the venom of Scorpio Centruroides margaritatus. Margatoxin preferentially inhibits voltage-dependent potassium channels Kv1.3 with an IC50 value around 50 pM (20 fold more potent than Charybdotoxin) and irreversibly inhibits the proliferation response of human T-cells at 20 μM concentration. Uses: Potassium channel blockers. Synonyms: MgTX. Grades: >98%. CAS No. 145808-47-5. Molecular formula: C178H286N52O50S7. Mole weight: 4178.96. BOC Sciences 3
Margatoxin Potent KV1.3 channel blocker (IC50 = 36 pM). Displays no effect at calcium-activated channels. Reduces VEGF-induced transmembrane calcium influxes and nitric oxide production in human endothelial cells. Group: Biochemicals. Grades: Purified. CAS No. 145808-47-5. Pack Sizes: 100ug. Molecular Formula: C178H286N52O50S7, Sequence: TIINVKCTSPKQCLPPCKAQFG QSAGAKCMNGKCKCYPH. US Biological Life Sciences. USBiological 5
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