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| Product | Description | |
|---|---|---|
| Marimastat | Marimastat (BB2516) is a broad spectrum and orally bioavailable inhibitor of MMPs , with potent activity against MMP-9 ( IC 50 =3 nM), MMP-1 ( IC 50 =5 nM), MMP-2 ( IC 50 =6 nM), MMP-14 ( IC 50 =9 nM) and MMP-7 ( IC 50 =13 nM), used in the treatment of cancer. Marimastat (BB2516) is an angiogenesis and metastasis inhibitor, which limits the growth and production of blood vessels. As an antimetatstatic agent it prevents malignant cells from breaching the basement membranes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BB2516; TA2516. CAS No. 154039-60-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12169. |  |
| Marimastat | Marimastat. Group: Biochemicals. Alternative Names: [2S-[N4 (R*) , 2R*, 3S*]]-N4-[2, 2-Dimethyl-1-[ (methylamino) carbonyl]propyl]-N1, 2-dihydroxy-3- (2-methylpropyl) butanediamide; BB 2516; GI 5712; KB-R 8898; TA 2516; (2S, 3R) -N4-[ (1S) -2, 2-Dimethyl-1-[ (methylamino) carbonyl]propyl]-N1, 2-dihydroxy-3- (2-methylpropyl) butanediamide. Grades: Highly Purified. CAS No. 154039-60-8. Pack Sizes: 5mg. Molecular Formula: C15H29N3O5, Molecular Weight: 331.41. US Biological Life Sciences. |  Worldwide |
| Marimastat | Marimastat is an orally-active synthetic broad spectrum inhibitor of MMPs (IC50 values are 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively). Synonyms: BB-2516; BB2516; BB 2516; TA-2516; TA2516; TA 2516; Marimastat; N-[2,2-dimethyl-1- (methylcarbamoyl)propyl]-2- [hydroxy-(hydroxycarbamoyl)methyl]- 4- methyl-pentanamide; (2S,3R)-3-(((1S)-2,2-dimethyl-1-(methylcarbamoxy)propyl)carboyl)-2-hydroxy-5-methylhexanohydroxamic Acid; (2S,3R)-3-{(S)-[2,2-dimethyl-1-(methylcarbamoyl) propyl]carbamoyl}-2-hydroxy-5-methylhexanohydroxamic acid. CAS No. 154039-60-8. Molecular formula: C15H29N3O5. Mole weight: 331.413. |  |
| Marimastat ( (2S, 3R) -N4-[ (1S) -2, 2-Dimethyl-1-[ (-[ (methylamino) carbonyl]propyl]-N1, 2-dihydroxy-3- (2-methylpropyl) butanediamide, BB-2516, TA-2516) | A broad spectrum matrix metalloprotease (MMP) inhibitor with IC50 values of 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively. It covalently binds to the zinc(II) ion in the active site of MMPs, thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
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