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| Product | Description | |
|---|---|---|
| Masitinib | Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit ( IC 50 =200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β ( IC 50 s=540/800 nM), Lyn ( IC 50 = 510 nM for LynB), Lck , and, to a lesser extent, FGFR3 and FAK. Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AB1010. CAS No. 790299-79-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10209. |  |
| Masitinib | Masitinib is an orally bioavailable and multi-targeted protein tyrosine kinase inhibitor with potential antineoplastic activity. Synonyms: AB-1010; AB 1010; AB1010; Masitinib. Brand name: Kinavet; Masivet. CAS No. 790299-79-5. Molecular formula: C28H30N6OS. Mole weight: 498.649. |  |
| Masitinib mesylate | Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit ( IC 50 =200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β ( IC 50 s=540/800 nM), Lyn ( IC 50 = 510 nM for LynB), Lck , and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AB-1010 mesylate. CAS No. 1048007-93-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10209A. | |
| Masitinib mesylate | Masitinib mesylate is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Synonyms: AB-1010; AB 1010; AB1010. Grades: >98%. CAS No. 1048007-93-7. Molecular formula: C29H34N6O4S2. Mole weight: 594.75. | |
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