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| Product | Description | |
|---|---|---|
| MAZ51 | MAZ51 is an indolinone that blocks the ligand-induced autophosphorylation of VEGFR-3 by VEGF-C. It was shown to inhibit proliferation and induce apoptosis of tumor cell lines. Synonyms: (E)-3-((4-(dimethylamino)naphthalen-1-yl)methylene)indolin-2-one; 3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one; EX-A1914. Grades: ≥95%. CAS No. 163655-37-6. Molecular formula: C21H18N2O. Mole weight: 314.4. |  |
| MAZ51 | MAZ51 is a selective inhibitor of VEGFR-3 (Flt-4) tyrosine kinase. MAZ51 inhibits VEGF-C-induced activation of VEGFR-3 without blocking VEGF-C-mediated stimulation of VEGFR2. MAZ51 had no effect on ligand-induced autophosphorylation of EGFR, IGF-1R and PDGFR?. MAZ51 blocks proliferation and induces apoptosis in a wide variety of tumor cells. Antitumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 163655-37-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116624. |  |
| VEGFR3 Kinase Inhibitor, MAZ51 - CAS 163655-37-6 | The VEGFR3 Kinase Inhibitor, MAZ51, also referenced under CAS 163655-37-6, controls the biological activity of VEGFR3 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. |  |
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