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McN-A 343 McN-A 343. Group: Biochemicals. Grades: Purified. CAS No. 55-45-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
McN-A 343 McN-A 343 is a partial agonist with similar affinity at all five muscarinic acetylcholine receptor subtypes and its relative selectivity depends on a higher efficacy at the M1 (and M4) subtypes. Its selectivity for M1 over other muscarinic receptor types appears to arise from a high efficacy at M1 receptors. Uses: Nicotinic agonists. Synonyms: [4-(m-Chlorophenylcarbamoyloxy)-2-butynyl]trimethylammonium Chloride; 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium Chloride; m-Chlorocarbanilate (4-Hydroxy-2-butynyl)trimethylammonium Chloride; A 343; McN 343; McN-A 343-11. Grades: ≥99% by HPLC. CAS No. 55-45-8. Molecular formula: C14H18Cl2N2O2. Mole weight: 317.21. BOC Sciences 10
McN-A-343 McN-A-343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 reduces inflammation and oxidative stress in an experimental model of ulcerative colitis [1] [2]. McN-A-343 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 55-45-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107648. MedChemExpress MCE
McNA343 McNA343 is a partial agonist of muscarinic acetylcholine receptors. It induces contraction of isolated human umbilical veins. Uses: Designed for use in research and industrial production. Additional or Alternative Names: McNA343; McN-A343; McN A343; McNA 343; McNA-343; McNA343. Product Category: Agonists. Appearance: Solid powder. CAS No. 55-45-8. Molecular formula: C14H18Cl2N2O2. Mole weight: 317.21. Purity: >98%. IUPACName: 4-[[[(3-chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium, monochloride. Canonical SMILES: C[N+](C)(C)CC#CCOC(NC1=CC=CC(Cl)=C1)=O.[Cl-]. Product ID: ACM55458-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.

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