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| Product | Description | |
|---|---|---|
| MCOPPB | MCOPPB is a drug which acts as a potent and selective agonist for the nociceptin receptor, with a pKi of 10.07 and much weaker activity at other opioid receptors. MCOPPB exhibited potent anxiolytic effects in mouse models, and inhibited signaling through nociceptin receptor in the mouse brain. Synonyms: 1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole. Grades: >98%. CAS No. 1028969-49-4. Molecular formula: C26H40N4. Mole weight: 408.634. |  |
| MCOPPB triHydrochloride | The trihydrochloride salt form of MCOPPB, an effective full agonist of nociceptin receptor, could be a good antianxiety agent with few side-effects. pKi: 10.07. Uses: The trihydrochloride salt form of mcoppb could be a good antianxiety agent with few side-effects. Synonyms: 1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole; trihydrochloride; MCOPPBtrihydrochloride; 1028969-49-4; 1108147-88-1; 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-Benzimidazoletrihydrochloride. Grades: 95%. CAS No. 1108147-88-1. Molecular formula: C26H40N4.3HCL. Mole weight: 518.01. | |
| MCOPPB Trihydrochloride | A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis. Group: Biochemicals. Alternative Names: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole TriHydrochloride; PF-01678059. Grades: Highly Purified. CAS No. 1108147-88-1. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| MCOPPB trihydrochloride hydrate | >98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
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