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| Product | Description | |
|---|---|---|
| Mdivi-1 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| Mdivi-1 | Mdivi-1 Inhibitor. Uses: Scientific use. Product Category: T1907. CAS No. 338967-87-6. |  |
| Mdivi-1 | Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Synonyms: Mdivi-1; Mdivi 1; Mdivi1; Mitochondrial Division Inhibitor 1. Grades: >98%. CAS No. 338967-87-6. Molecular formula: C15H10Cl2N2O2S. Mole weight: 353.22. |  |
| Mdivi-1 | Mdivi-1 is a selective dynamin-related protein 1 ( Drp1 ) inhibitor. Mdivi-1 is a mitochondrial division/ mitophagy inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mitochondrial division inhibitor 1. CAS No. 338967-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15886. |  |
| Mitochondrial Division Inhibitor, mdivi-1 - CAS 338967-87-6 | The Mitochondrial Division Inhibitor, mdivi-1, also referenced under CAS 338967-87-6, controls the biological activity of yeast Dnm1 and mammalian Drp1. Group: Fluorescence/luminescence spectroscopy. | |
| Mitochondrial Fusion Promoter, M1 ( (E) -4-Chloro-2- (1- (2- (2, 4, 6-trichlorophenyl) hydrazono) ethyl) phenol) | A cell-permeable phenylhydrazone that restores mitochondrial tubular network formation in MEF lacking either of the two outer mitochondrial membrane (OMM) mitofusins (EC50=5.3 and 4.42 mM, respectively, in Mfn1 or Mfn2 knockout MEF cells) or in MPP+-treated SH-SY5Y cells (5uM 24h), but not in MEF lacking both Mfn1/2 or the inner mitochondrial membrane (IMM) fusion mediator Opa1 (optic atrophy1). M1 (5uM 24h) is reported to boost the downregulated ATP5A & ATP5B protein level in Mfn1 or Mfn2 knockout MEF to the wild-type MEF level and ATPase inhibitor oligomycin at 5uM is shown to completely offset the mitochondrial fusion effect by 5uM M1 in Mfn1 knockout MEF. Comparing to mdivi-1, M1 exerts its effect via promoting fusion rather than inhibiting fission or division. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
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