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L-3-Nitrophenylalanine is a derivative of L-Phenylalanine, and is used in the photocleavage of polypeptide backbones. L-Phenylalanine is an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded ami. Synonyms: L-3-Nitrophenylalanine; L-3-(m-nitrophenyl)-alanine; NSC 21948. Grades: ≥ 98% (HPLC, Chiral purity). CAS No. 19883-74-0. Molecular formula: C9H10N2O4. Mole weight: 210.19.
(2S)-2-Amino-3-(4-morpholin-4-ylphenyl)propanoic Acid is a possible impurity of Melphalan which is an antineoplastic. Synonyms: (2S)-2-Amino-3-(4-morpholin-4-ylphenyl)propanoic Acid; 4-(4-Morpholinyl)-L-phenylalanine. Grades: > 95%. CAS No. 1270153-04-2. Molecular formula: C13H18N2O3. Mole weight: 250.29.
Methoxy Dechloromelphalan is a derivative of Melphalan which is an antineoplastic. Synonyms: Methoxy Dechloromelphalan Dihydrochloride; 4-[(2-Chloroethyl)(2-methoxyethyl)amino]-L-phenylalanine Dihydrochlorid. Grades: > 95%. Molecular formula: C14H23Cl3N2O3. Mole weight: 373.7.
Melphalan Impurity J
2-Chloroethoxy Dechloromelphalan is a possible impurity of Melphalan which is an antineoplastic. Synonyms: 2-Chloroethoxy Dechloromelphalan; (S)-2-Amino-3-(4-((2-(2-chloroethoxy)ethyl)(2-chloroethyl)amino)phenyl)propanoic Acid. Grades: > 95%. Molecular formula: C15H22Cl2N2O3. Mole weight: 349.25.
2-Chloroethoxy Dechloromelphalan is a possible impurity of Melphalan (M216900) which is an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C15H22Cl2N2O3. US Biological Life Sciences.
Worldwide
2-Chloroethoxy Dechloromelphalan-d4
2-Chloroethoxy Dechloromelphalan-d4 is labelled 2-Chloroethoxy Dechloromelphalan (C368070), a possible impurity of Melphalan (M216900) which is an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C15H18D4Cl2N2O3, Molecular Weight: 353.28. US Biological Life Sciences.
(2S)-2-Amino-3-(4-morpholin-4-ylphenyl)propanoic Acid is a possible impurity of Melphalan which is an antineoplastic. Group: Biochemicals. Alternative Names: 4-(4-Morpholinyl)-L-phenylalanine, Melphalan Impurity B. Grades: Highly Purified. CAS No. 1270153-04-2. Pack Sizes: 2.5mg. Molecular Formula: C13H18N2O3. US Biological Life Sciences.
(2S)-2-Amino-3-(4-morpholin-4-ylphenyl)propanoic Acid-d4 is labelled (2S)-2-Amino-3-(4-morpholin-4-ylphenyl)propanoic Acid (A618690), a possible impurity of Melphalan (M216900) which is an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C13H14D4N2O3, Molecular Weight: 254.32. US Biological Life Sciences.
Worldwide
3-Amino-3,4-dihydroquinolin-2(1H)-one
3-Amino-3,4-dihydroquinolin-2(1H)-one is an intermediate used to prepare thienopyrroles as glycogen phosphorylase inhibitors. It is also an impurity of Melphalan (M216900). Group: Biochemicals. Grades: Highly Purified. CAS No. 40615-17-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H10N2O, Molecular Weight: 162.19. US Biological Life Sciences.
3-Amino-6-[N,N-bis(3-chloropropyl)amino]-1,2,3,4-tetrahydro-2-oxo-quinoline Hydrochloride is an impurity/intermediate of Melphalan (M216900), which is antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H22Cl3N3O, Molecular Weight: 366.71. US Biological Life Sciences.
Worldwide
Hydroxy Melphalan
Hydroxymelphalan is an analogue of Melphalan, an antineoplastic. Synonyms: 4-[(2-Chloroethyl)(2-hydroxyethyl)amino]-L-phenylalanine; Melphalan EP Impurity D. Grades: > 95%. CAS No. 61733-01-5. Molecular formula: C13H19ClN2O3. Mole weight: 286.75.
Melphalan Dimer Hydrochloride
Melphalan Dimer is an impurity from the synthesis of Melphanan, an antineoplastic. Synonyms: 4-[[2-[[4-[Bis(2-chloroethyl)amino]-L-phenylalanyl]oxy]ethyl](2-chloroethyl)amino]-L-phenylalanine Hydrochloride. Grades: > 95%. Molecular formula: C26H35Cl3N4O4ยท(HCl)x. Mole weight: 573.94.
Melphalan EP lmpurity A
Melphalan EP lmpurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 72143-20-5. Molecular Formula: C13H20N2O4. Mole Weight: 268.31. Catalog: APB72143205.
Melphalan EP lmpurity B
Melphalan EP lmpurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1259994-01-8. Molecular Formula: C13H18N2O3. Mole Weight: 250.3. Catalog: APB1259994018.
Melphalan EP lmpurity C
Melphalan EP lmpurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 573704-41-3. Molecular Formula: C11H15ClN2O2. Mole Weight: 242.7. Catalog: APB573704413.
Melphalan EP lmpurity D
Melphalan EP lmpurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 61733-01-5. Molecular Formula: C13H19ClN2O3. Mole Weight: 286.76. Catalog: APB61733015.
Melphalan EP lmpurity E
Melphalan EP lmpurity E. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H23ClN2O3. Mole Weight: 314.81. Catalog: APB11384.
Melphalan EP lmpurity F
Melphalan EP lmpurity F. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C13H17Cl3N2O2. Mole Weight: 339.64. Catalog: APB11383.
Melphalan EP lmpurity G
Melphalan EP lmpurity G. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H35Cl3N4O4. Mole Weight: 573.94. Catalog: APB11385.
Melphalan EP lmpurity H
Melphalan EP lmpurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 88457-23-2. Molecular Formula: C14H20Cl2N2O2. Mole Weight: 319.23. Catalog: APB88457232.
Melphalan EP lmpurity I
Melphalan EP lmpurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 573704-40-2. Molecular Formula: C14H21ClN2O3. Mole Weight: 300.78. Catalog: APB573704402.
Melphalan EP lmpurity J
Melphalan EP lmpurity J. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H22Cl2N2O3. Mole Weight: 349.25. Catalog: APB11386.
Melphalan Isopropyl Ester Dihydrochloride Salt
Melphalan isopropyl ester is an impurity of Melphalan, a nitrogen mustard analogue that is used as a chemotherapeutic agent for various types of cancers (such as multiple myeloma and plasma-cell leukemia). Synonyms: 4-[Bis(2-chloroethyl)amino]-L-phenylalanine 1-Methylethyl Ester Dihydrochloride Salt. Grades: > 95%. Molecular formula: C16H26Cl4N2O2. Mole weight: 420.2.
Melphalan lmpurity 1
Melphalan lmpurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 660-68-4. Molecular Formula: C3H12ClN. Mole Weight: 109.6. Catalog: APB660684.
Melphalan lmpurity 11
Melphalan lmpurity 11. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H23ClN2O3. Mole Weight: 314.81. Catalog: APB11394.
Melphalan lmpurity 12
Melphalan lmpurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2724878-97-9. Molecular Formula: C13H17Cl3N2O2. Mole Weight: 339.64. Catalog: APB2724878979.
Melphalan lmpurity 13
Melphalan lmpurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C28H39Cl3N4O4. Mole Weight: 601.99. Catalog: APB11395.
Melphalan lmpurity 14
Melphalan lmpurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 685847-78-3. Molecular Formula: C13H18Cl2N2O3. Mole Weight: 321.2. Catalog: APB685847783.
Melphalan lmpurity 2
Melphalan lmpurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 93963-19-0. Molecular Formula: C19H18N2O7. Mole Weight: 386.36. Catalog: APB93963190.
Melphalan lmpurity 3
Melphalan lmpurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H27ClN2O6. Mole Weight: 486.95. Catalog: APB11388.
Melphalan lmpurity 4
Melphalan lmpurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C23H25ClN2O5. Mole Weight: 444.91. Catalog: APB11387.
Melphalan lmpurity 5
Melphalan lmpurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H21ClN2O5. Mole Weight: 416.86. Catalog: APB11389.
Melphalan lmpurity 6
Melphalan lmpurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H21ClN2O4. Mole Weight: 400.86. Catalog: APB11391.
Melphalan lmpurity 7
Melphalan lmpurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C23H25ClN2O4. Mole Weight: 428.91. Catalog: APB11392.
Melphalan lmpurity 8
Melphalan lmpurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C23H26N2O5. Mole Weight: 410.47. Catalog: APB11390.
Melphalan lmpurity 9
Melphalan lmpurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H20Cl2N2O4. Mole Weight: 435.3. Catalog: APB11393.
PX-478 dihydrochloride
PX-478 is an HIF-1alpha inhibitor and an orally active small molecule with potential antineoplastic activity. Although its mechanism of action has yet to be fully elucidated, HIF1-alpha inhibitor PX-478 appears to inhibit hypoxia-inducible factor 1-alpha (HIF1A) expression, which may result in decreased expression of HIF1A downstream target genes important to tumor growth and survival, a reduction in tumor cell proliferation, and the induction of tumor cell apoptosis. The inhibitory effect of this agent is independent of the tumor suppressor genes VHL and p53 and may be related to derangements in glucose uptake and metabolism due to inhibition of glucose transporter-1 (Glut-1). PX-478 has excellent activity against established human tumor xenografts, providing tumor regressions with prolonged growth delays which correlate positively with HIF-1 levels. PX-478 is a highly water soluble molecule, with good i.v., i.p. and p.o. antitumor activity. It is rapidly absorbed following oral and i.p. administration and gives excellent Cmax and AUC via these routes. Synonyms: PX-478 2HCl; PX-478 hydrochloride; Melphalan N-Oxide Impurity HCl; Melphalan N-Oxide Impurity hydrochloride; L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoamino]-, dihydrochloride; L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoamino]-, hydrochloride (1:2). Grades: > 98%. CAS No. 685898-44-6. Molecular formula: C13H18Cl2N2O3.2HCl. Mole weight: 394.1.
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