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Menaquinone 6. Group: Biochemicals. Alternative Names: (all-E)-2-(3,7,11,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaenyl)-3-methyl-1,4-naphthalenedione; Farnoquinone; MK6. Grades: Highly Purified. CAS No. 84-81-1. Pack Sizes: 5mg. Molecular Formula: C41H56O2. US Biological Life Sciences.
Worldwide
Menaquinone 6
Menaquinone 6 is a active product found in Wolinella succinogenes. Menaquinone 6 is a form of vitamin K2 (HY-109569) that has antimicrobial activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 84-81-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138137.
Menaquinone 6
Menaquinone 6 is a vitamin K2 homolog. Synonyms: Farnoquinone; Menaquinone-6; Vitamin MK6; Vitamin K2(30); 2-[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaenyl]-3-methylnaphthalene-1,4-dione. CAS No. 84-81-1. Molecular formula: C41H56O2. Mole weight: 580.897.
1,4-dihydroxy-2-naphthoyl-CoA hydrolase
This enzyme participates in the synthesis of menaquinones, phylloquinone, as well as several plant pigments. The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 does not accept benzoyl-CoA or phenylacetyl-CoA as substrates. Group: Enzymes. Synonyms: menI (gene name); ydiL (gene name). Enzyme Commission Number: EC 3.1.2.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3561; 1,4-dihydroxy-2-naphthoyl-CoA hydrolase; EC 3.1.2.28; menI (gene name); ydiL (gene name). Cat No: EXWM-3561.
1,4-dihydroxy-2-naphthoyl-CoA synthase
This enzyme is involved in the synthesis of 1,4-dihydroxy-2-naphthoate, a branch point metabolite leading to the biosynthesis of menaquinone (vitamin K2, in bacteria), phylloquinone (vitamin K1 in plants), and many plant pigments.The coenzyme A group is subsequently removed from the product by EC 3.1.2.28, 1,4-dihydroxy-2-naphthoyl-CoA hydrolase. Group: Enzymes. Synonyms: naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Enzyme Commission Number: EC 4.1.3.36. CAS No. 61328-42-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4913; 1,4-dihydroxy-2-naphthoyl-CoA synthase; EC 4.1.3.36; 61328-42-5; naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Cat No: EXWM-4913.
2,6-Dimethyl-8-(phenylmethoxy)-2,6-octadien-1-ol
2,6-Dimethyl-8-(phenylmethoxy)-2,6-octadien-1-ol is an intermediate in the synthesis of Menaquinone 6 (M218590). Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone-6 were the major isoprenoid quinones found in membrane preparations of Campylobacter jejuni and Campylobacter fetus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5g, 10g. Molecular Formula: C17H24O2. US Biological Life Sciences.
Worldwide
2,6-Dimethyl-8-(phenylmethoxy)-2,6-octadienal
2,6-Dimethyl-8-(phenylmethoxy)-2,6-octadienal is an intermediate in the synthesis of Menaquinone 6 (M218590). Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone-6 were the major isoprenoid quinones found in membrane preparations of Campylobacter jejuni and Campylobacter fetus. Group: Biochemicals. Grades: Highly Purified. CAS No. 117010-63-6. Pack Sizes: 5g, 10g. Molecular Formula: C17H22O2, Molecular Weight: 258.36. US Biological Life Sciences.
Requires Mg2+ for maximal activity. This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the products of the reaction were (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate (SHCHC), pyruvate and CO2 but it is now known that two separate enzymes are involved: this enzyme and EC 4.2.99.20, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. Under basic conditions, the product can spontaneously lose pyruvate to form SHCHC. Group: Enzymes. Synonyms: SEPHCHC synthase; MenD. Enzyme Commission Number: EC 2.2.1.9. CAS No. 1112282-73-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2036; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase; EC 2.2.1.9; 1112282-73-1; SEPHCHC synthase; MenD. Cat No: EXWM-2036.
This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the reactions carried out by this enzyme and EC 2.2.1.9, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase, were carried out by a single enzyme but this has since been disproved. Group: Enzymes. Synonyms: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase; 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase; SHCHC synthase; MenH; YfbB. Enzyme Commission Number: EC 4.2.99.20. CAS No. 122007-88-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5266; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; EC 4.2.99.20; 122007-88-9; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase; 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase; SHCHC synthase; MenH; YfbB. Cat No: EXWM-5266.
(2E,6E)-Farnesyl diphosphate and geranylgeranyl diphosphate are less effective as substrates than geranyl diphosphate. The enzyme is involved in the synthesis of the side chain of menaquinone-9. In Oryza sativa the enzyme SPS2 is involved in providing solanesyl diphosphate for plastoquinone-9 formation. Group: Enzymes. Synonyms: nonaprenyl diphosphate synthase (ambiguous); solanesyl diphosphate synthase (ambiguous); SolPP synthase (ambiguous); SPP-synthase (ambiguous); SPP synthase (ambiguous); solanesyl-diphosphate synthase (ambiguous); OsSPS2. Enzyme Commission Number: EC 2.5.1.84. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2822; all-trans-nonaprenyl-diphosphate synthase [geranyl-diphosphate specific]; EC 2.5.1.84; nonaprenyl diphosphate synthase (ambiguous); solanesyl diphosphate synthase (ambiguous); SolPP synthase (ambiguous); SPP-synthase (ambiguous); SPP synthase (ambiguous); solanesyl-diphosphate synthase (ambiguous); OsSPS2. Cat No: EXWM-2822.
aminodeoxyfutalosine nucleosidase
The enzyme, found in several bacterial species, catalyses a step in a modified futalosine pathway for menaquinone biosynthesis. While the enzyme from some organisms also has the activity of EC 3.2.2.9, adenosylhomocysteine nucleosidase, the enzyme from Chlamydia trachomatis is specific for 6-amino-6-deoxyfutalosine. Group: Enzymes. Synonyms: AFL nucleosidase; aminofutalosine nucleosidase; methylthioadenosine nucleosidase; MqnB. Enzyme Commission Number: EC 3.2.2.30. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3985; aminodeoxyfutalosine nucleosidase; EC 3.2.2.30; AFL nucleosidase; aminofutalosine nucleosidase; methylthioadenosine nucleosidase; MqnB. Cat No: EXWM-3985.
aminodeoxyfutalosine synthase
This enzyme is a member of the 'AdoMet radical' (radical SAM) family. S-Adenosyl-L-methionine acts as both a radical generator and as the source of the transferred adenosyl group. The enzyme, found in several bacterial species, is part of the futalosine pathway for menaquinone biosynthesis. Group: Enzymes. Synonyms: MqnE; AFL synthase; aminofutalosine synthase; S-adenosyl-L-methionine:3-[(1-carboxyvinyl)-oxy]benzoate adenosyltransferase (bicarbonate-hydrolysing, 6-amino-6-deoxyfutalosine-forming). Enzyme Commission Number: EC 2.5.1.120. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2736; aminodeoxyfutalosine synthase; EC 2.5.1.120; MqnE; AFL synthase; aminofutalosine synthase; S-adenosyl-L-methionine:3-[(1-carboxyvinyl)-oxy]benzoate adenosyltransferase (bicarbonate-hydrolysing, 6-amino-6-deoxyfutalosine-forming). Cat No: EXWM-2736.
Menaquinon-9
Menaquinon-9. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Phylloquinone,(Z); Phytonadione,(Z); [R-[R*,R*-(Z)]]-2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione; 2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl]naphthoquinone; 2-methyl-3-((E)-3,7,11,15-tetramethyl-hex. Product Category: Heterocyclic Organic Compound. Appearance: yellow crystals. CAS No. 863-61-3. Molecular formula: C56H80O2. Mole weight: 883.748068;g/mol. Purity: 0.96. IUPACName: trisodium;(3E)-3-[[4-[4-[[4-[(2Z)-2-(7-amino-1-oxo-3-sulfonatonaphthalen-2-ylidene)hydrazinyl]-7-sulfonatonaphthalen-1-yl]diazenyl]phenyl]phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylate. Canonical SMILES: C1=CC(=CC=C1C2=CC=C(C=C2)N=NC3=C4C=C(C=CC4=C(C=C3)NN=C5C(=CC6=C(C5=O)C=C(C=C6)N)S(=O)(=O)[O-])S(=O)(=O)[O-])NN=C7C=CC(=O)C(=C7)C(=O)[O-].[Na+].[Na+].[Na+]. Density: 0.994 g/cm³. Product ID: ACM863613. Alfa Chemistry ISO 9001:2015 Certified. Categories: Menaquinone.
Menaquinone 4. Group: Biochemicals. Alternative Names: (E,E,E)-2-Methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthalenedione; 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone; Glakay. Grades: Highly Purified. CAS No. 863-61-6. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C31H40O2. US Biological Life Sciences.
Worldwide
Menaquinone 4
Menaquinone 4 is a homolog of vitamin K2 with four isoprene residue in its side chain. Menaquinone 4 is the most common type of vitamin K2 and can be used for the pain of osteoporosis. Uses: Hemostatics. Synonyms: 1,4-Naphthalenedione, 2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-; 1,4-Naphthalenedione, 2-methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-, (E,E,E)-; 1,4-Naphthalenedione, 2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl]-; 2-Methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-1,4-naphthalenedione; 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone; Glakay; K-viton; Kaytwo; Menaquinone K4; Menatetrenone; MK-4; Vitamin K2; Vitamin K2(20); Vitamin K2-4; Vitamin MK 4. Grades: ≥95%. CAS No. 863-61-6. Molecular formula: C31H40O2. Mole weight: 444.65.
Menaquinone 4 2,3-epoxide
Menaquinone 4 2,3-epoxide. Group: Biochemicals. Alternative Names: 1a,7a-Dihydro-1a-methyl-7a-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-naphth[2,3-b]oxirene-2,7-dione; (E, E, E) -1a, 7a-Dihydro-1a-methyl-7a- (3, 7, 11, 15-tetramethyl-2, 6, 10, 14-hexadecatetraenyl) naphth[2, 3-b]oxirene-2, 7-dione; Menaquinone 4 epoxide. Grades: Highly Purified. CAS No. 72908-86-2. Pack Sizes: 10mg. Molecular Formula: C31H40O3. US Biological Life Sciences.
Worldwide
Menaquinone 4-d7 (Mixture of cis-trans isomers)
Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 4-d7 is the labeled analogue of Menaquinone 4. Menaquinone-4 is the most common type of vitamin K2 and is known as a hemostatic agent and is used as adjunctive therapy for the pain of osteoporosis. Group: Biochemicals. Alternative Names: (E,E,E)-2-Methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthalenedione-d7; 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone-d7; Glakay-d7; Kaytwo-d7; MK4-d7; Menaquinone K4-d7; Menatetrenone-d7; Vitamin K2(20)-d7; Vitamin MK 4-d7. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Menaquinone 4 (Mixture of cis-trans isomers)
Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 4 has four isoprene residue in its side chain and is also commonly refered to as menatetrenone. Menaquinone-4 is the most common type of vitamin K2 and is known as a hemostatic agent and is used as adjunctive therapy for the pain of osteoporosis. Group: Biochemicals. Alternative Names: (E,E,E)-2-Methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthalenedione; 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone; Glakay; Kaytwo; MK4; Menaquinone K4; Menatetrenone; Vitamin K2(20); Vitamin MK 4. Grades: Highly Purified. CAS No. 863-61-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Menaquinone 4 (Vitamin K2 (20), MK 4)
Menaquinone 4 (MK-4) is the predominant homolog of vitamin K2 and is composed of a naphthoquinone base with four isoprenoid units in the side chain.1 It is formed primarily via conversion of vitamin K1 (Item No. 21051) in vivo and accumulates in various tissues, including the brain.2,3 MK-4 halts the cell cycle at the G phase in HepG2, Hep3B, and Huh7 hepatocellular carcinoma cells in a concentration-dependent manner.4 It also inhibits I?B kinase (IKK) activity, I?Ba phosphorylation, and the transcriptional activity of NF-?B. Vitamin K2 may have a role in bone metabolism.1. Group: Biochemicals. Alternative Names: (E,E,E)-2-Methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthalenedione; Menatetrenone; Vitamin K2(20); Kaytwo; MK 4. Grades: Purified. CAS No. 863-61-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C31H40O2. US Biological Life Sciences.
Worldwide
Menaquinone 5
Menaquinone 5. Group: Biochemicals. Alternative Names: 2-Methyl-3-[(2E,6E,10E,14E)-3,7,11,15,19-pentamethyl-2,6,10,14,18-eicosapentaen-1-yl]-1,4-naphthalenedione; 2-Methyl-3-farnesylgeranyl-1,4-naphthoquinone; Vitamin MK 5. Grades: Highly Purified. CAS No. 1182-68-9. Pack Sizes: 5mg. Molecular Formula: C36H48O2. US Biological Life Sciences.
Worldwide
Menaquinone 7
Menaquinone 7 belongs to a class of K2-vitamin homologs originally discovered as the anti-hemorrhagic factors. Menaquinone 7 has been identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins, such as osteocalcin and matrix-Gla protein, which plays a crucial role in building and maintaining overall bone health. Applications: A bioactive cofactor for the carboxylation reaction of gla-proteins. Group: Coenzymes. Synonyms: (all-E)-2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione; Vitamin K2(35); Menaquinone K7. CAS No. 2124-57-4. Purity: ≥90%. Mole weight: 649. Form: Solid. (all-E)-2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione; Vitamin K2(35); Menaquinone K7; Menaquinone 7; 2124-57-4. Cat No: COEC-093.
Menaquinone 7 (Vitamin K2 MK 7)
Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 7 belongs to the class of K2-Vitamins homologs. Menaquinone 7 has been identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins such as osteocalcin and matrix-Gla protein, which plays a crucial role in building and maintaining overall bone health. Group: Biochemicals. Alternative Names: (all-E)-2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione; Vitamin K2(35); Menaquinone K7; Vitamin MK 7. Grades: Highly Purified. CAS No. 2124-57-4,27670-94-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C46H64O2. US Biological Life Sciences.
Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 9 is a form of vitamin K2 which acts as a prothrombogenic agent and is also a functional electron transfer component in nitrate reductase. Group: Biochemicals. Alternative Names: 2-Methyl-3-[(2E, 6E, 10E, 14E, 18E, 22E, 26E, 30E)-3, 7, 11, 15, 19, 23, 27, 31, 35-nonamethyl-2, 6, 10, 14, 18, 22, 26, 30, 34-hexatriacontanonaen-1-yl]-. Grades: Highly Purified. CAS No. 523-39-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
o-succinylbenzoate-CoA ligase
O-succinylbenzoate CoA ligase (EC 6.2.1.26), encoded from the menE gene in Escherichia coli, catalyzes the fifth reaction in the synthesis of menaquinone (vitamin K2). This pathway is called 1, 4-dihydroxy-2-naphthoate biosynthesis I. Vitamin K is a quinone that serves as an electron transporter during anaerobic respiration. This process of anaerobic respiration allows the bacteria to generate the energy required to survive. Group: Enzymes. Synonyms: o-succinylbenzoyl-coenzyme A synthetase; o-succinylbenzoate:CoA ligase (AMP-forming). Enzyme Commission Number: EC 6.2.1.26. CAS No. 72506-70-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5684; o-succinylbenzoate-CoA ligase; EC 6.2.1.26; 72506-70-8; o-succinylbenzoyl-coenzyme A synthetase; o-succinylbenzoate:CoA ligase (AMP-forming). Cat No: EXWM-5684.
phenylacetyl-CoA dehydrogenase
The enzyme from Thauera aromatica is a membrane-bound molybdenum-iron-sulfur protein. The enzyme is specific for phenylacetyl-CoA as substrate. Phenylacetate, acetyl-CoA, benzoyl-CoA, propanoyl-CoA, crotonyl-CoA, succinyl-CoA and 3-hydroxybenzoyl-CoA cannot act as substrates. The oxygen atom introduced into the product, phenylglyoxylyl-CoA, is derived from water and not molecular oxygen. Duroquinone, menaquinone and 2,6-dichlorophenolindophenol (DCPIP) can act as acceptor, but the likely physiological acceptor is ubiquinone. A second enzyme, EC 3.1.2.25, phenylacetyl-CoA hydrolase, converts the phenylglyoxylyl-CoA formed into phenylglyoxylate. Group: Enzymes. Synonyms: phenylacetyl-CoA:acceptor oxidoreductase. Enzyme Commission Number: EC 1.17.5.1. CAS No. 210756-43-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1094; phenylacetyl-CoA dehydrogenase; EC 1.17.5.1; 210756-43-7; phenylacetyl-CoA:acceptor oxidoreductase. Cat No: EXWM-1094.