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| Product | Description | |
|---|---|---|
| 2-Methylbenzofuran | 1g Pack Size. Group: Building Blocks, Organics. Formula: C9H8O. CAS No. 4265-25-2. Prepack ID 43971397-1g. Molecular Weight 132.16. See USA prepack pricing. |  |
| 3-Methylbenzofuran-2-carbaldehyde | Heterocyclic Organic Compound. Alternative Names: Ambnee4002706, MolPort-002-017-465, ZINC00035262, 3-Methyl-benzofuran-2-carbaldehyde, CID136938, 2-Benzofurancarboxaldehyde, 3-methyl-, 2-Benzofurancarboxaldehyde, 3-methyl-,, BAS 10143765, 1199-07-1. CAS No. 1199-07-1. Molecular formula: C10H8O2. Mole weight: 160.17. Purity: 0.96. IUPACName: 3-methyl-1-benzofuran-2-carbaldehyde. Canonical SMILES: CC1=C(OC2=CC=CC=C12)C=O. Density: 1.192g/cm³. Catalog: ACM1199071. |  |
| 3-Methylbenzofuran-2-carboxylic acid | 3-Methylbenzofuran-2-carboxylic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 24673-56-1. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences. |  Worldwide |
| 5-Chloro-3-methylbenzofuran | Heterocyclic Organic Compound. Alternative Names: 5-CHLORO-3-METHYLBENZOFURAN. CAS No. 1125-41-3. Molecular formula: C9H7ClO. Mole weight: 166.6. Catalog: ACM1125413. | |
| Afabicin | Afabicin (formerly Debio 1450, AFN-1720) is a prodrug of afabicin desphosphono, an enoyl-acyl carrier protein reductase (FabI) inhibitor, and is a first-in-class antibiotic with a novel mode of action to specifically target fatty acid synthesis in Staphylococcus spp. Group: Inhibitors. Alternative Names: Afabicin; Debio 1450; Debio-1450; Debio1450; AFN-1720; AFN 1720; AFN1720. CAS No. 1518800-35-5. Molecular formula: C23H24N3O7P. Mole weight: 485.43. Appearance: Solid powder. Purity: >98%. IUPACName: (E)-(6-(3-(methyl((3-methylbenzofuran-2-yl)methyl)amino)-3-oxoprop-1-en-1-yl)-2-oxo-3,4-dihydro-1,8-naphthyridin-1(2H)-yl)methyl dihydrogen phosphate. Canonical SMILES: O=P (O) (OCN1C (CCC2=CC (/C=C/C (N (C)CC (O3)=C (C)C4=C3C=CC=C4)=O)=CN=C12)=O)O. Catalog: ACM1518800355. | |
| AFN-1252 | AFN-1252, also known as AFN-12520000; API-1252; Debio-1452, is FASII Inhibitor which is potentially for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long elimination half-live and efficacy in animal models. AFN-1252 efficiently blocked daptomycin-induced phospholipid decoy production, even in the case of isolates resistant to AFN-1252, which prevented the inactivation of daptomycin and resulted in sustained bacterial killing. In turn, daptomycin prevented the fatty acid-dependent emergence of AFN-1252-resistant isolates in vitro. Group: Inhibitors. Alternative Names: AFN-1252; AFN 1252; AFN1252; API-1252; API1252; API 1252; AFN12520000; AFN 12520000; AFN12520000; Debio1452; Debio 1452; Debio1452. CAS No. 620175-39-5. Molecular formula: C22H21N3O3. Mole weight: 375.43. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide. Canonical SMILES: O=C (N (C)CC1=C (C)C2=CC=CC=C2O1)/C=C/C3=CC (CC4)=C (N=C3)NC4=O. Catalog: ACM620175395. | |
| BMS-344577 | BMS-344577 is aroylguanidine-based lactam derivative, which is a potent FXa inhibitor (FXa IC(50)=4 nM, EC(2xPT)=7 microM). Uses: Aroylguanidine-based factor xa inhibitor. Synonyms: BMS-344577; BMS344577; BMS 344577; UNII-U259PQB19A; CHEMBL570867; U259PQB19A; BDBM35316; BDBM50328724; N5-[[[(3S)-Hexahydro-2-oxo-1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1H-azepin-3-yl]imino][(2-methyl-5-benzofuranyl)amino]methyl]-N2,N2-dimethyl-2,5-pyridinedicarboxamide;(S,E)-N2,N2-dimethyl-N5-(N'-(2-methylbenzofuran-5-yl)-N-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)carbamimidoyl)pyridine-2,5-dicarboxamide. Grades: ≥95%. CAS No. 288079-93-6. Molecular formula: C31H37N7O5. Mole weight: 587.67. |  |
| BNC-105 | BNC105 is a novel compound being developed by Bionomics as a Vascular Disrupting Agent (VDA) for treatment of cancer. VDAs are drugs that disrupt the blood vessels that nourish tumours. BNC105 acts as a tubulin polymerization inhibitor and displays 80-fold higher potency against endothelial cells than that of CA4P. CA4P is a VDA currently under evaluation in phase III clinical trials. BNC105 is more potent and offers a wider therapeutic window. CA4P produces 90% vascular disruption at its no observed adverse event level (NOAEL), whereas BNC105 causes 95% vascular disruption at 1/8th of its NOAEL. Tissue distribution analysis of BNC105 in tumor-bearing mice showed that while the drug is cleared from all tissues 24 hours after administration, it is still present at high concentrations within the solid tumor mass. Furthermore, BNC105 treatment causes tumor regressions with complete tumor clearance in 20% of treated animals. Group: Inhibitors. Alternative Names: BCN105; BCN-105; BCN 105. CAS No. 945771-74-4. Molecular formula: C20H20O7. Mole weight: 372.37. Appearance: Beige fluffy powder. Purity: >98%. IUPACName: (7-hydroxy-6-methoxy-2-methylbenzofuran-3-yl)(3,4,5-trimethoxyphenyl)methanone. Canonical SMILES: O=C (C1=C (C)OC2=C (O)C (OC)=CC=C12)C3=CC (OC)=C (OC)C (OC)=C3. Catalog: ACM945771744. | |
| Methyl 2-methyl-1-benzofuran-5-carboxylate | Heterocyclic Organic Compound. Alternative Names: methyl 2-methyl-1-benzofuran-5-carboxylate, 117379-97-2, SCHEMBL6091417, CTK6J0348, JRCRSXNCAUQMOU-UHFFFAOYSA-N, MolPort-006-067-221, ALBB-005589, SBB047848, STK503489, ZINC34925450, AKOS000321452, RTR-058824, methyl 2-methylbenzofuran-5-carboxylate, KB-94607, 5-(Methoxycarbonyl)-2-methylbenzo[b]furan, KB-255834, TR-058824, BB 0260877, methyl 2-methyl-1-benzo[b]furan-5-carboxylate, 2-Methylbenzo[b]furan-5-carboxylic acid methyl ester. CAS No. 117379-97-2. Molecular formula: C11H10O3. Mole weight: 190.2. Purity: 0.96. IUPACName: methyl 2-methyl-1-benzofuran-5-carboxylate. Canonical SMILES: CC1=CC2=C(O1)C=CC(=C2)C(=O)OC. Catalog: ACM117379972. | |
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