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| Product | Description | |
|---|---|---|
| Methylenediphosphonic acid | for molecular studies & mass spectrometry. Group: Mass spectrometry (ms). |  |
| Medronic Acid (Methylenebiphosphonic Acid, Methylenediphosphonic Acid, Methanebisphosphonic Acid, Methanediphosphonic Acid, MDP) | Radioactive imaging agent. Group: Biochemicals. Alternative Names: Methylenebiphosphonic Acid; Methylenediphosphonic Acid; Methanebisphosphonic Acid; Methanediphosphonic Acid; MDP. Grades: Highly Purified. CAS No. 1984-15-2. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| MMP-2 Inhibitor IV (Bone Resorption Inhibitor, (4'-chlorobiphenyl-4ylsulfonamido) methylenediphosphonic Acid) | A cell-permeable, bisphosphonate derivative that displays nanomolar activity against MMP-2 (IC50=37nM), with good selectivity over MMP-8 (320nM), MMP-9 (>1uM), and MMP-14 (> 1uM). It is shown to inhibit osteoclast activity in a macrophage cell line, J774 (IC50=1.7uM), which is more potent compared with other bisphosphonates such as Alendronate, (IC50=30uM), and Zolendronate (7.8uM), without observable cytotoxicity in HepG2 cells. At 25uM, it abolishes the formation of actin rings, which are functional structures that are typical of resorbing osteoclasts, at activity levels comparable with those of zolendronic acid, inhibits bone resportion in vitro, and demonstrates cytotoxic properties in murine osteoclasts. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Medronic acid | Medronic acid. Group: Biochemicals. Alternative Names: Methylenebiphosphonic acid; Methylenediphosphonic acid; Methanebisphosphonic acid. Grades: Highly Purified. CAS No. 1984-15-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: CH6O6P2. US Biological Life Sciences. | Worldwide |
| 5'-Guanylylmethylenediphosphonate | 5'-Guanylylmethylenediphosphonate is a crucial compound used in the research of various diseases serving as a potent inhibitor of adenylate cyclase, which can help regulate intracellular cyclic AMP levels. Additionally, 5'-Guanylylmethylenediphosphonate is used in research studies to investigate the mechanism of enzyme inhibition and to develop potential therapeutic strategies targeting adenylate cyclase. Synonyms: guanosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid; 5'-guanylylmethylenebisphosphonate; GMP-P(CH2)P; GMP-PCP; Guanosine 5'-(β,γ-methylene)triphosphate; Guanosine 5'-[β,γ-methylene]triphosphoric acid; Guanylyl methylenediphosphonate. Grade: 95%. CAS No. 13912-93-1. Molecular formula: C11H18N5O13P3. Mole weight: 521.21. |  |
| Guanosine 5'-monophosphate,monoanhydride with(phosphonomethyl)phosphonic acid | Guanosine 5'-monophosphate,monoanhydride with(phosphonomethyl)phosphonic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: guanosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid;5'-guanylylmethylenebisphosphonate;GMP-P(CH2)P;GMP-PCP;Guanosine 5'-(β,γ-methylene)triphosphate;Guanosine 5'-[β,γ-methylene]triphosphoric acid;Guanylyl methylenediphosphonate. Product Category: Heterocyclic Organic Compound. CAS No. 13912-93-1. Molecular formula: C11H18N5O13P3. Product ID: ACM13912931. Alfa Chemistry ISO 9001:2015 Certified. |  |
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