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1-Methylnicotinamide Chloride is an anti-inflammatory that can reverse the dysfunction of the endothelium caused by inflammation. Group: Biochemicals. Grades: Highly Purified. CAS No. 1005-24-9. Pack Sizes: 50mg, 100mg. Molecular Formula: C7H9ClN2O. US Biological Life Sciences.
2,6-Dichloro-4-methylnicotinamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 38841-54-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H6Cl2N2O, Molecular Weight: 205.04. US Biological Life Sciences.
Worldwide
2-Amino-5-bromo-6-methylnicotinamide
Bromine Series. CAS No. 1003711-26-9. Catalog: ACM1003711269.
2-Chloro-N-methylnicotinamide
2-Chloro-N-methylnicotinamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 52943-20-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H7ClN2O, Molecular Weight: 170.6. US Biological Life Sciences.
Worldwide
4-Methylnicotinamide
4-Methylnicotinamide. Group: Biochemicals. Alternative Names: 4-Methyl-3-pyridinecarboxamide; NSC 131712; NSC 30041. Grades: Highly Purified. CAS No. 7250-52-4. Pack Sizes: 500mg. Molecular Formula: C7H8N2O, Molecular Weight: 136.15. US Biological Life Sciences.
Worldwide
6-Methylnicotinamide
A nicotinamide derivative that inhibits state 3 respiration in isolated rat liver mitochondria. It is toxic to rat B65 neuroblastoma cells and is used in studies associated with early symptoms of Parkinson's disease. Group: Biochemicals. Alternative Names: 6-Methyl-3-Pyridinecarboxamide; 6-Methylnicotinic Acid Amide; 6-Methylpyridine-3-carboxamide. Grades: Highly Purified. CAS No. 6960-22-1. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
6-Methylnicotinamide ≥98.5%
6-Methylnicotinamide ≥98.5%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 6960-22-1. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Heterocyclic Organic Compound. Alternative Names: Nicotinic acid methylamide. CAS No. 114-33-0. Molecular formula: C7H8N2O. Mole weight: 136.15. Appearance: White to off-white solid. Purity: 0.99. IUPACName: N-Methylpyridine-3-carboxamide. Canonical SMILES: CNC(=O)C1=CN=CC=C1. Density: 1.1778 g/cm³. Catalog: ACM114330.
N-Methylnicotinamide
N-Methylnicotinamide is an endogenous metabolite with antithrombotic effect. N-Methylnicotinamide via production/release of prostacyclin inhibits arterial thrombosis development. N-Methylnicotinamide is also the N-methylation product from nicotinamide catalyzed by N-methyltransferase within nicotinate and nicotinamide metabolism pathway. N-Methylnicotinamide is a potential biomarker in miR-1291-altered pancreatic cell metabolism and tumorigenesis [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 114-33-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-124124.
GSK-189254 free base
GSK-189254 is a potent and selective H3-receptor inverse agonist. It has subnanomolar affinity for the H3 receptor and selectivity of over 10,000x for H3 over other histamine receptor subtypes. Animal studies have shown it to possess not only stimulant and nootropic effects, but also analgesic action suggesting a role for H3 receptors in pain processing in the spinal cord. GSK-189,254 and several other related drugs are currently being investigated as a treatment for Alzheimer's disease and other forms of dementia, as well as possible use in the treatment of conditions such as narcolepsy, or neuropathic pain which do not respond well to conventional analgesic drugs. Group: Agonists. Alternative Names: GSK189254; GSK-189254; GSK 189254; GSK-189254 free base. CAS No. 720690-73-3. Molecular formula: C21H25N3O2. Mole weight: 351.45. Appearance: solid powder. Purity: >98%. IUPACName: 6-((3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)oxy)-N-methylnicotinamide. Canonical SMILES: O=C (NC)C1=CN=C (OC2=CC=C3CCN (C4CCC4)CCC3=C2)C=C1. Catalog: ACM720690733.
Nicotinamide N-Methyltransferase from Human, Recombinant
Nicotinamide N-Methyltransferase (NNMT) methylates nicotinamide and other pyridine containing compounds. NNMT transfers a methyl group from S-adenosylmethionine (SAM) to nitrogen N1 of nicotinamide to produce 1-methylnicotinamide (MNA) and S-adenosylhomocysteine. MNA is a messenger molecule that increases neurite branching, serves as an anti-thrombotic, and has anti-inflammatory properties. The role of NNMT overexpression in cancers may be to alter epigenetic methylation patterns in two ways: by lowering the intracellular concentration of SAM, required by methyltransferase enzymes, and by depleting the available NAD+ by transforming nicotinamide to MNA. Sirtuins use NAD+ as a substrate to alter protein acetylation and ribosylation, including histone targets. Group: Enzymes. Synonyms: NNMT. Enzyme Commission Number: E.C. 2.1.1.1. Purity: > 95% by SDS-PAGE. Mole weight: 42.6 kDa. Stability: As supplied, 6 months from the QC date provided on the Certificate of Analysis, when stored properly. Storage: Store at -80°C. Form: Liquid. Source: recombinant N-terminal His- and SUMO-tagged protein expressed in E. coli. Species: Human. NNMT; Nicotinamide N-Methyltransferase. Cat No: NATE-1656.
Nikethamide Impurity 7
Nikethamide Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-ethyl-N-methylnicotinamide. Molecular Formula: C9H12N2O. Mole Weight: 164.20. Catalog: APB01378.
Cefpiramide
It is produced by the strain of Semisynthetic third generation cephalosporin for injection. Its sodium salt is used in preparations. Cefpiramide binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted. Synonyms: Cefpiramide acid; Cefpiramido; Cefpiramidum; (6R,7R)-7-((R)-2-(4-Hydroxy-6-methylnicotinamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grades: 95%. CAS No. 70797-11-4. Molecular formula: C25H24N8O7S2. Mole weight: 612.64.
Cefpiramide sodium
Cefpiramide sodium. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (6R,7R)-7-((R)-2-(4-hydroxy-6-methylnicotinamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. CAS No. 74849-93-7. Molecular Formula: C25H25N8NaO7S2. Mole Weight: 636.63. Catalog: APB74849937.
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