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| Product | Description | |
|---|---|---|
| Methylene Blue | Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC) , monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue is a Tau aggregation inhibitor. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Basic Blue 9; CI-52015; Methylthioninium chloride. CAS No. 61-73-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-14536. |  |
| Methylene Blue | Methylene Blue, whose brand name is Calbiochem, inhibits tau filament formation (IC50 = 1.9 μM) and soluble guanylyl cyclase. Uses: Enzyme inhibitors. Synonyms: Methylene blue; CI52015; CI 52015; CI-52015; [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium; chloride; Blue N, Methylene; Blue, Methylene; Blue, Swiss; Chromosmon; Methylene Blue; Methylene Blue N; Methylthionine Chloride; Methylthioninium Chloride; N, Methylene Blue; Swiss Blue; Urolene Blue; 61-73-4. CAS No. 61-73-4. Molecular formula: C16H18ClN3S. Mole weight: 319.85. |  |
| Methylene blue hydrate | Methylene blue (Basic Blue 9) hydrate is a guanylyl cyclase (sGC) , monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue hydrate through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue hydrate is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue hydrate is a Tau aggregation inhibitor. Methylene blue hydrate reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Basic Blue 9 hydrate; CI-52015 hydrate; Methylthioninium chloride hydrate. CAS No. 122965-43-9. Pack Sizes: 1 g; 5 g. Product ID: HY-D0958. | |
| TRX-0237 mesylate | TRX-0237 mesylate is a second-generation tau protein aggregation inhibitor applicated for the treatment of AD (Alzheimer's disease) and frontotemporal dementia. TRX-0237 is the purified form of Methylene Blue, an old drug that has being widely used in Africa for the treatment of malaria, methemoglobinemia and other conditions for a long time. TRX-0237 is the stabilized, reduced form of methylthioninium chloride to improve the drug's absorption, bioavailability, and tolerability. TRX-0237 is in Phase I for Parkinson's disease, Phase II for Progressive supranuclear palsy and Phase III for Alzheimer's disease and Dementia. Uses: Parkinson's disease; progressive supranuclear palsy; alzheimer's disease; dementia. Synonyms: TRX-0237 mesylate; TRX 0237 mesylate; TRX0237 mesylate; Leucomethylene blue (Mesylate); AKOS026750731; CS-5553; AK-499443; HY-19948; CS 5553; AK 499443; HY 19948; CS5553; AK499443; HY19948; N3,N3,N7,N7-Tetramethyl-10H-phenothiazine-3,7-diamine dimethanesulfonate. Grades: 98%. CAS No. 1236208-20-0. Molecular formula: C18H27N3O6S3. Mole weight: 477.6. | |
| Methylthioninium for system suitability | European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. Uses: For analytical and research use. Group: Reagents. Alternative Names: Methylene Blue SG, Methylene Blue BP, ExternYamamoto Methylene Blue B, Methylene Blue 2BP, Methylene Blue 2BN, Methylene Blue D, NSC 617593, Ext D and C Blue No. 1, Swiss blue, Duasyn Basic Blue IAD, Basic Lake Blue, 3,7-Bis(dimethylamino)phenothiazin-5-ylium chloride (methylene blue), Methylene Blue NZ, C.I. Basic Blue 9, Methylene Blue HGG, Aizen Methylene Blue FZ, Tetramethylthionine chloride, BIVN 401, Methylene Blue FZ, Methylene Blue 2B, Izit Crystal Dye, Methylene Blue BD, Basic Blue 2B, Methylene Blue G, Methylene Blue A, Aizen Methylene Blue BH, Hidaco Methylene Blue Salt Free, C.I. Solvent Blue 8, Methylthionine chloride, Proveblue, Mitsui Methylene Blue, Leather Pure Blue HB, Methylene Blue chloride, Methylene Blue BBA, C.I. 52015, 3,7-Bis(dimethylamino)phenothiazin-5-ium chloride (1:1), Solvent Blue 8, Virostat, Methylene Blue Zinc Free, Calcozine Blue ZF, Maxilon Blue SG, Methylene Blue SP, Methylene Blue ZX, Methylene Blue NF, Methylenium ceruleum, Methylene Blue JFA, Methylene Blue Iad, Schultz 1038, Methylene Blue B, Methylene blue, Methylene Blue GZ, Methylene Blue BB, Methylene Blue N. CAS No. 61-73-4. IUPAC Name: 3-N,3-N,7-N,7-N-tetramethylphenothiazin-5-ium-3,7-diamine;chloride;hydrate. |  |
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