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| Product | Description | |
|---|---|---|
| methyltransferase cap1 | This enzyme catalyses the methylation of the ribose on the first transcribed nucleotide of mRNA or snRNA molecules, which may be either guanosine or adenosine. This methylation event is known as cap1, and occurrs in all mRNAs and snRNAs of higher eukaryotes, including insects, vertebrates and their viruses. The human enzyme can also methylate mRNA molecules that lack methylation on the capping 5'-triphosphoguanosine. Group: Enzymes. Synonyms: messenger ribonucleate nucleoside 2'-methyltransferase; messenger RNA (nucleoside-2'-)-methyltransferase; MTR1; cap1-MTase; mRNA (nucleoside-2'-O)-methyltransferase (ambiguous); S-adenosyl-L-methionine:mRNA (nucleoside-2'-O)-methyltransferase. Enzyme Commission Number: EC 2.1.1.57. CAS No. 61970-02-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1959; methyltransferase cap1; EC 2.1.1.57; 61970-02-3; messenger ribonucleate nucleoside 2'-methyltransferase; messenger RNA (nucleoside-2'-)-methyltransferase; MTR1; cap1-MTase; mRNA (nucleoside-2'-O)-methyltransferase (ambiguous); S-adenosyl-L-methionine:mRNA (nucleoside-2'-O)-methyltransferase. Cat No: EXWM-1959. |  |
| methyltransferase cap2 | The enzyme, found in higher eukaryotes including insects and vertebrates, and their viruses, methylates the ribose of the ribonucleotide at the second transcribed position of mRNAs and snRNAs. This methylation event is known as cap2. The human enzyme can also methylate mRNA molecules where the upstream purine ribonucleotide is not methylated (see EC 2.1.1.57, methyltransferase cap1), but with lower efficiency. Group: Enzymes. Synonyms: MTR2; cap2-MTase; mRNA (nucleoside-2'-O)-methyltransferase (ambiguous). Enzyme Commission Number: EC 2.1.1.296. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1903; methyltransferase cap2; EC 2.1.1.296; MTR2; cap2-MTase; mRNA (nucleoside-2'-O)-methyltransferase (ambiguous). Cat No: EXWM-1903. | |
| 10-hydroxydihydrosanguinarine 10-O-methyltransferase | This reaction is part of the pathway for synthesis of benzophenanthridine alkaloids in plants. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.119. CAS No. 144388-39-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1718; 10-hydroxydihydrosanguinarine 10-O-methyltransferase; EC 2.1.1.119; 144388-39-6. Cat No: EXWM-1718. | |
| 12-hydroxydihydrochelirubine 12-O-methyltransferase | This reaction is part of the pathway for synthesis of benzophenanthridine alkaloid macarpine in plants. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.120. CAS No. 158736-40-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1720; 12-hydroxydihydrochelirubine 12-O-methyltransferase; EC 2.1.1.120; 158736-40-4. Cat No: EXWM-1720. | |
| 16S rRNA (adenine1408-N1)-methyltransferase | The enzyme provides a panaminoglycoside-resistant nature through interference with the binding of aminoglycosides toward the A site of 16S rRNA through N1-methylation at position adenine1408. Group: Enzymes. Synonyms: kanamycin-apramycin resistance methylase; 16S rRNA:m1A1408 methyltransferase; KamB; NpmA; 16S rRNA m1A1408 methyltransferase. Enzyme Commission Number: EC 2.1.1.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1779; 16S rRNA (adenine1408-N1)-methyltransferase; EC 2.1.1.180; kanamycin-apramycin resistance methylase; 16S rRNA:m1A1408 methyltransferase; KamB; NpmA; 16S rRNA m1A1408 methyltransferase. Cat No: EXWM-1779. | |
| 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase | KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine1518 and adenine1519 in 16S rRNA. Strains lacking the methylase are resistant to kasugamycin. Group: Enzymes. Synonyms: S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; KsgA; ksgA methyltransferase. Enzyme Commission Number: EC 2.1.1.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1781; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; EC 2.1.1.182; S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; KsgA; ksgA methyltransferase. Cat No: EXWM-1781. | |
| 16S rRNA (cytidine1402-2'-O)-methyltransferase | RsmI catalyses the 2'-O-methylation of cytidine1402 and RsmH (EC 2.1.1.199) catalyses the N4-methylation of cytidine1402 in 16S rRNA. Both methylations are necessary for efficient translation initiation at the UUG and GUG codons. Group: Enzymes. Synonyms: RsmI; YraL. Enzyme Commission Number: EC 2.1.1.198. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1797; 16S rRNA (cytidine1402-2'-O)-methyltransferase; EC 2.1.1.198; RsmI; YraL. Cat No: EXWM-1797. | |
| 16S rRNA (cytidine1409-2'-O)-methyltransferase | The bifunctional enzyme from Mycobacterium tuberculosis 2'-O-methylates cytidine1409 in helix 44 of 16S rRNA and cytidine1920 in helix 69 of 23S rRNA (cf. EC 2.1.1.226, 23S rRNA (cytidine1920-2'-O)-methyltransferase). Group: Enzymes. Synonyms: TlyA (ambiguous). Enzyme Commission Number: EC 2.1.1.227. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1830; 16S rRNA (cytidine1409-2'-O)-methyltransferase; EC 2.1.1.227; TlyA (ambiguous). Cat No: EXWM-1830. | |
| 16S rRNA (cytosine1402-N4)-methyltransferase | RsmH catalyses the N4-methylation of cytosine1402 andRsmI (EC 2.1.1.198) catalyses the 2'-O-methylation of cytosine1402 in 16S rRNA. Both methylations are necessary for efficient translation initiation at the UUG and GUG codons. Group: Enzymes. Synonyms: RsmH; MraW. Enzyme Commission Number: EC 2.1.1.199. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1798; 16S rRNA (cytosine1402-N4)-methyltransferase; EC 2.1.1.199; RsmH; MraW. Cat No: EXWM-1798. | |
| 16S rRNA (cytosine1407-C5)-methyltransferase | The enzyme specifically methylates cytosine1407 at C5 in 16S rRNA. Group: Enzymes. Synonyms: RNA m5C methyltransferase YebU; RsmF; YebU. Enzyme Commission Number: EC 2.1.1.178. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1776; 16S rRNA (cytosine1407-C5)-methyltransferase; EC 2.1.1.178; RNA m5C methyltransferase YebU; RsmF; YebU. Cat No: EXWM-1776. | |
| 16S rRNA (cytosine967-C5)-methyltransferase | The enzyme specifically methylates cytosine967 at C5 in 16S rRNA. Group: Enzymes. Synonyms: rsmB (gene name); fmu (gene name); 16S rRNA m5C967 methyltransferase. Enzyme Commission Number: EC 2.1.1.176. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1774; 16S rRNA (cytosine967-C5)-methyltransferase; EC 2.1.1.176; rsmB (gene name); fmu (gene name); 16S rRNA m5C967 methyltransferase. Cat No: EXWM-1774. | |
| 16S rRNA (guanine1207-N2)-methyltransferase | The enzyme reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA. The enzyme specifically methylates guanine1207 at N2 in 16S rRNA. Group: Enzymes. Synonyms: m2G1207 methyltransferase. Enzyme Commission Number: EC 2.1.1.172. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1770; 16S rRNA (guanine1207-N2)-methyltransferase; EC 2.1.1.172; m2G1207 methyltransferase. Cat No: EXWM-1770. | |
| 16S rRNA (guanine1405-N7)-methyltransferase | The enzyme from the antibiotic-producing bacterium Micromonospora zionensis specifically methylates guanine1405 at N7 in 16S rRNA, thereby rendering the ribosome resistant to 4,6-disubstituted deoxystreptamine aminoglycosides, which include gentamicins and kanamycins. Group: Enzymes. Synonyms: methyltransferase Sgm; m7G1405 Mtase; Sgm Mtase; Sgm; sisomicin-gentamicin methyltransferase; sisomicin-gentamicin methylase; GrmA; RmtB; RmtC; ArmA. Enzyme Commission Number: EC 2.1.1.179. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1777; 16S rRNA (guanine1405-N7)-methyltransferase; EC 2.1.1.179; methyltransferase Sgm; m7G1405 Mtase; Sgm Mtase; Sgm; sisomicin-gentamicin methyltransferase; sisomicin-gentamicin methylase; GrmA; RmtB; RmtC; ArmA. Cat No: EXWM-1777. | |
| 16S rRNA (guanine1516-N2)-methyltransferase | The enzyme specifically methylates guanine1516 at N2 in 16S rRNA. Group: Enzymes. Synonyms: yhiQ (gene name); rsmJ (gene name); m2G1516 methyltransferase. Enzyme Commission Number: EC 2.1.1.242. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1845; 16S rRNA (guanine1516-N2)-methyltransferase; EC 2.1.1.242; yhiQ (gene name); rsmJ (gene name); m2G1516 methyltransferase. Cat No: EXWM-1845. | |
| 16S rRNA (guanine527-N7)-methyltransferase | The enzyme specifically methylates guanine527 at N7 in 16S rRNA. Group: Enzymes. Synonyms: ribosomal RNA small subunit methyltransferase G; 16S rRNA methyltransferase RsmG; GidB; rsmG (gene name). Enzyme Commission Number: EC 2.1.1.170. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1768; 16S rRNA (guanine527-N7)-methyltransferase; EC 2.1.1.170; ribosomal RNA small subunit methyltransferase G; 16S rRNA methyltransferase RsmG; GidB; rsmG (gene name). Cat No: EXWM-1768. | |
| 16S rRNA (guanine966-N2)-methyltransferase | The enzyme efficiently methylates guanine966 of the assembled 30S subunits in vitro. Protein-free 16S rRNA is not a substrate for RsmD. The enzyme specifically methylates guanine966 at N2 in 16S rRNA. Group: Enzymes. Synonyms: yhhF (gene name);rsmD (gene name); m2G966 methyltransferase. Enzyme Commission Number: EC 2.1.1.171. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1769; 16S rRNA (guanine966-N2)-methyltransferase; EC 2.1.1.171; yhhF (gene name);rsmD (gene name); m2G966 methyltransferase. Cat No: EXWM-1769. | |
| 16S rRNA (uracil1498-N3)-methyltransferase | The enzyme specifically methylates uracil1498 at N3 in 16S rRNA. Group: Enzymes. Synonyms: DUF558 protein; YggJ; RsmE; m3U1498 specific methyltransferase. Enzyme Commission Number: EC 2.1.1.193. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1793; 16S rRNA (uracil1498-N3)-methyltransferase; EC 2.1.1.193; DUF558 protein; YggJ; RsmE; m3U1498 specific methyltransferase. Cat No: EXWM-1793. | |
| 18S rRNA (guanine1575-N7)-methyltransferase | The enzyme, found in eukaryotes, is involved in pre-rRNA processing. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae. Group: Enzymes. Synonyms: 18S rRNA methylase Bud23; BUD23 (gene name). Enzyme Commission Number: EC 2.1.1.309. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1917; 18S rRNA (guanine1575-N7)-methyltransferase; EC 2.1.1.309; 18S rRNA methylase Bud23; BUD23 (gene name). Cat No: EXWM-1917. | |
| 21S rRNA (uridine2791-2'-O)-methyltransferase | The enzyme catalyses the methylation of uridine2791 of mitochondrial 21S rRNA. Group: Enzymes. Synonyms: MRM2 (gene name); mitochondrial 21S rRNA methyltransferase; mitochondrial rRNA MTase 2. Enzyme Commission Number: EC 2.1.1.168. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1765; 21S rRNA (uridine2791-2'-O)-methyltransferase; EC 2.1.1.168; MRM2 (gene name); mitochondrial 21S rRNA methyltransferase; mitochondrial rRNA MTase 2. Cat No: EXWM-1765. | |
| 23S rRNA (adenine1618-N6)-methyltransferase | The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit, but neither the completely assembled 50 S subunits nor completely deproteinized 23 S rRNA. Group: Enzymes. Synonyms: rRNA large subunit methyltransferase F; YbiN protein; rlmF (gene name); m6A1618 methyltransferase. Enzyme Commission Number: EC 2.1.1.181. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1780; 23S rRNA (adenine1618-N6)-methyltransferase; EC 2.1.1.181; rRNA large subunit methyltransferase F; YbiN protein; rlmF (gene name); m6A1618 methyltransferase. Cat No: EXWM-1780. | |
| 23S rRNA (adenine2030-N6)-methyltransferase | The recombinant RlmJ protein is most active in methylating deproteinized 23S ribosomal subunit, and does not methylate the completely assembled 50S subunits. Group: Enzymes. Synonyms: YhiR protein; rlmJ (gene name); m6A2030 methyltransferase. Enzyme Commission Number: EC 2.1.1.266. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1871; 23S rRNA (adenine2030-N6)-methyltransferase; EC 2.1.1.266; YhiR protein; rlmJ (gene name); m6A2030 methyltransferase. Cat No: EXWM-1871. | |
| 23S rRNA (adenine2085-N6)-dimethyltransferase | ErmC is a methyltransferase that confers resistance to the macrolide-lincosamide-streptogramin B group of antibiotics by catalysing the methylation of 23S rRNA at adenine2085. Group: Enzymes. Synonyms: ErmC' methyltransferase; ermC methylase;ermC 23S rRNA methyltransferase; rRNA:m6A methyltransferase ErmC'; ErmC'; rRNA methyltransferase ErmC'. Enzyme Commission Number: EC 2.1.1.184. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1783; 23S rRNA (adenine2085-N6)-dimethyltransferase; EC 2.1.1.184; ErmC' methyltransferase; ermC methylase;ermC 23S rRNA methyltransferase; rRNA:m6A methyltransferase ErmC'; ErmC'; rRNA methyltransferase ErmC'. Cat No: EXWM-1783. | |
| 23S rRNA (adenine2503-C2)-methyltransferase | Contains an [4Fe-4S] cluster. This enzyme is a member of the 'AdoMet radical' (radical SAM) family. S-Adenosyl-L-methionine acts as both a radical generator and as the source of the appended methyl group. RlmN first transfers an CH2 group to a conserved cysteine (Cys355 in Escherichia coli), the generated radical from a second S-adenosyl-L-methionine then attacks the methyl group, exctracting a hydrogen. The formed radical forms a covalent intermediate with the adenine group of the tRNA. RlmN is an endogenous enzyme used by the cell to refine functions of the ribosome in protein synthesis. The enzyme methylates adenosine by a radical mechanism with CH2 from the S-adenosyl-L-methionine and retention of the hydrogen at C-2 of adenosine2503 of 23S rRNA. It will also methylate 8-methyladenosine2503 of 23S rRNA. cf. EC 2.1.1.224 [23S rRNA (adenine2503-C8)-methyltransferase]. Group: Enzymes. Synonyms: RlmN; YfgB; Cfr. Enzyme Commission Number: EC 2.1.1.192. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1792; 23S rRNA (adenine2503-C2)-methyltransferase; EC 2.1.1.192; RlmN; YfgB; Cfr. Cat No: EXWM-1792. | |
| 23S rRNA (adenine2503-C8)-methyltransferase | This enzyme is a member of the 'AdoMet radical' (radical SAM) family. S-Adenosyl-L-methionine acts as both a radical generator and as the source of the appended methyl group. It contains an [4Fe-S] cluster. Cfr is an plasmid-acquired methyltransferase that protects cells from the action of antibiotics. The enzyme methylates adenosine at position 2503 of 23S rRNA by a radical mechanism, transferring a CH2 group from S-adenosyl-L-methionine while retaining the hydrogen at the C-8 position of the adenine. Cfr first transfers an CH2 group to a conserved cysteine (Cys338 in Staphylococcus aureus), the generated radical from a second S-adenosyl-L-methionine then attacks the methyl group, exctracting a hydrogen. The formed radical forms a covalent intermediate with the adenine group of the tRNA. The enzyme will also methylate 2-methyladenine produced by the action of EC 2.1.1.192 [23S rRNA (adenine2503-C2)-methyltransferase]. Group: Enzymes. Synonyms: Cfr (gene name). Enzyme Commission Number: EC 2.1.1.224. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1827; 23S rRNA (adenine2503-C8)-methyltransferase; EC 2.1.1.224; Cfr (gene name). Cat No: EXWM-1827. | |
| 23S rRNA (adenosine1067-2'-O)-methyltransferase | The methylase that is responsible for autoimmunity in the thiostrepton producer Streptomyces azureus, renders ribosomes completely resistant to thiostrepton. Group: Enzymes. Synonyms: 23S rRNA A1067 2'-methyltransferase; thiostrepton-resistance methylase; nosiheptide-resistance methyltransferase. Enzyme Commission Number: EC 2.1.1.230. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1833; 23S rRNA (adenosine1067-2'-O)-methyltransferase; EC 2.1.1.230; 23S rRNA A1067 2'-methyltransferase; thiostrepton-resistance methylase; nosiheptide-resistance methyltransferase. Cat No: EXWM-1833. | |
| 23S rRNA (cytidine1920-2'-O)-methyltransferase | The bifunctional enzyme from Mycobacterium tuberculosis 2'-O-methylates cytidine1920 in helix 69 of 23S rRNA and cytidine1409 in helix 44 of 16S rRNA (cf. EC 2.1.1.227, 16S rRNA (cytidine1409-2'-O)-methyltransferase). These methylations result in increased susceptibility to the antibiotics capreomycin and viomycin. Group: Enzymes. Synonyms: TlyA (ambiguous). Enzyme Commission Number: EC 2.1.1.226. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1829; 23S rRNA (cytidine1920-2'-O)-methyltransferase; EC 2.1.1.226; TlyA (ambiguous). Cat No: EXWM-1829. | |
| 23S rRNA (cytidine2498-2'-O)-methyltransferase | 23S rRNA (cytidine2498-2'-O)-methyltransferase (EC 2.1.1.186, YgdE, rRNA large subunit methyltransferase M, RlmM) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (cytidine2498-2'-O-)-methyltransferase. Group: Enzymes. Synonyms: YgdE; rRNA large subunit methyltransferase M; RlmM. Enzyme Commission Number: EC 2.1.1.186. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1785; 23S rRNA (cytidine2498-2'-O)-methyltransferase; EC 2.1.1.186; YgdE; rRNA large subunit methyltransferase M; RlmM. Cat No: EXWM-1785. | |
| 23S rRNA (cytosine1962-C5)-methyltransferase | The enzyme specifically methylates cytosine1962 at C5 in 23S rRNA. Group: Enzymes. Synonyms: RlmI; rRNA large subunit methyltransferase I; YccW. Enzyme Commission Number: EC 2.1.1.191. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1791; 23S rRNA (cytosine1962-C5)-methyltransferase; EC 2.1.1.191; RlmI; rRNA large subunit methyltransferase I; YccW. Cat No: EXWM-1791. | |
| 23S rRNA (guanine1835-N2)-methyltransferase | The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate. The enzyme specifically methylates guanine1835 at N2 in 23S rRNA. Group: Enzymes. Synonyms: ygjO (gene name); rlmG (gene name); ribosomal RNA large subunit methyltransferase G. Enzyme Commission Number: EC 2.1.1.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1772; 23S rRNA (guanine1835-N2)-methyltransferase; EC 2.1.1.174; ygjO (gene name); rlmG (gene name); ribosomal RNA large subunit methyltransferase G. Cat No: EXWM-1772. | |
| 23S rRNA (guanine2069-N7)-methyltransferase | The enzyme specifically methylates guanine2069 at position N7 in 23S rRNA. In γ-proteobacteria the enzyme also catalyses EC 2.1.1.173, 23S rRNA (guanine2445-N2)-methyltransferase, while in β-proteobacteria the activities are carried out by separate proteins. The enzyme from the γ-proteobacterium Escherichia coli has RNA unwinding activity as well. Group: Enzymes. Synonyms: rlmK (gene name); 23S rRNA m7G2069 methyltransferase. Enzyme Commission Number: EC 2.1.1.264. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1869; 23S rRNA (guanine2069-N7)-methyltransferase; EC 2.1.1.264; rlmK (gene name); 23S rRNA m7G2069 methyltransferase. Cat No: EXWM-1869. | |
| 23S rRNA (guanine2445-N2)-methyltransferase | The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate. The enzyme specifically methylates guanine2445 at N2 in 23S rRNA. Group: Enzymes. Synonyms: ycbY (gene name); rlmL (gene name). Enzyme Commission Number: EC 2.1.1.173. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1771; 23S rRNA (guanine2445-N2)-methyltransferase; EC 2.1.1.173; ycbY (gene name); rlmL (gene name). Cat No: EXWM-1771. | |
| 23S rRNA (guanine2535-N1)-methyltransferase | Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis. To protect itself from the antibiotic, Streptomyces viridochromogenes utilizes two methyltransferases, 23S rRNA (guanine2535-N1)-methyltransferase and EC 2.1.1.208 [23S rRNA (uridine2479-2-O)-methyltransferase], whose actions confer avilamycin resistance to the RNA. Group: Enzymes. Synonyms: AviRa. Enzyme Commission Number: EC 2.1.1.209. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1810; 23S rRNA (guanine2535-N1)-methyltransferase; EC 2.1.1.209; AviRa. Cat No: EXWM-1810. | |
| 23S rRNA (guanine745-N1)-methyltransferase | The enzyme specifically methylates guanine745 at N1 in 23S rRNA. Group: Enzymes. Synonyms: Rlma(I); Rlma1; 23S rRNA m1G745 methyltransferase; YebH; RlmAI methyltransferase; ribosomal RNA(m1G)-methylase (ambiguous); rRNA(m1G)methylase (ambiguous); RrmA (ambiguous); 23S rRNA:m1G745 methyltransferase. Enzyme Commission Number: EC 2.1.1.187. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1786; 23S rRNA (guanine745-N1)-methyltransferase; EC 2.1.1.187; Rlma(I); Rlma1; 23S rRNA m1G745 methyltransferase; YebH; RlmAI methyltransferase; ribosomal RNA(m1G)-methylase (ambiguous); rRNA(m1G)methylase (ambiguous); RrmA (ambiguous); 23S rRNA:m1G745 methyltransferase. Cat No: EXWM-1786. | |
| 23S rRNA (guanine748-N1)-methyltransferase | The enzyme specifically methylates guanine748 at N1 in 23S rRNA. The methyltransferase RlmAII confers resistance to the macrolide antibiotic tylosin in the drug-producing strain Streptomyces fradiae. Group: Enzymes. Synonyms: Rlma(II); Rlma2; 23S rRNA m1G748 methyltransferase; RlmaII; Rlma II; tylosin-resistance methyltransferase RlmA(II); TlrB; rRNA large subunit methyltransferase II. Enzyme Commission Number: EC 2.1.1.188. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1787; 23S rRNA (guanine748-N1)-methyltransferase; EC 2.1.1.188; Rlma(II); Rlma2; 23S rRNA m1G748 methyltransferase; RlmaII; Rlma II; tylosin-resistance methyltransferase RlmA(II); TlrB; rRNA large subunit methyltransferase II. Cat No: EXWM-1787. | |
| 23S rRNA (guanosine2251-2'-O)-methyltransferase | The enzyme catalyses the methylation of guanosine2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. Group: Enzymes. Synonyms: rlmB (gene name); yifH (gene name). Enzyme Commission Number: EC 2.1.1.185. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1784; 23S rRNA (guanosine2251-2'-O)-methyltransferase; EC 2.1.1.185; rlmB (gene name); yifH (gene name). Cat No: EXWM-1784. | |
| 23S rRNA (pseudouridine1915-N3)-methyltransferase | YbeA does not methylate uridine at position 1915. Group: Enzymes. Synonyms: YbeA; RlmH; pseudouridine methyltransferase; m3ψ methyltransferase; ψ1915-specific methyltransferase; rRNA large subunit methyltransferase H. Enzyme Commission Number: EC 2.1.1.177. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1775; 23S rRNA (pseudouridine1915-N3)-methyltransferase; EC 2.1.1.177; YbeA; RlmH; pseudouridine methyltransferase; m3ψ methyltransferase; ψ1915-specific methyltransferase; rRNA large subunit methyltransferase H. Cat No: EXWM-1775. | |
| 23S rRNA (uracil1939-C5)-methyltransferase | The enzyme specifically methylates uracil1939 at C5 in 23S rRNA. The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues. Group: Enzymes. Synonyms: RumA; RNA uridine methyltransferase A; YgcA. Enzyme Commission Number: EC 2.1.1.190. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1790; 23S rRNA (uracil1939-C5)-methyltransferase; EC 2.1.1.190; RumA; RNA uridine methyltransferase A; YgcA. Cat No: EXWM-1790. | |
| 23S rRNA (uracil747-C5)-methyltransferase | The enzyme specifically methylates uracil747 at C5 in 23S rRNA. Group: Enzymes. Synonyms: YbjF; RumB; RNA uridine methyltransferase B. Enzyme Commission Number: EC 2.1.1.189. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1788; 23S rRNA (uracil747-C5)-methyltransferase; EC 2.1.1.189; YbjF; RumB; RNA uridine methyltransferase B. Cat No: EXWM-1788. | |
| 23S rRNA (uridine2479-2'-O)-methyltransferase | Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis. To protect itself from the antibiotic, Streptomyces viridochromogenes utilizes two methyltransferases, 23S rRNA (uridine2479-2'-O)-methyltransferase and EC 2.1.1.209 [23S rRNA (guanine2535-N1)-methyltransferase], whose actions confer avilamycin resistance to the RNA. Group: Enzymes. Synonyms: AviRb. Enzyme Commission Number: EC 2.1.1.208. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1809; 23S rRNA (uridine2479-2'-O)-methyltransferase; EC 2.1.1.208; AviRb. Cat No: EXWM-1809. | |
| 23S rRNA (uridine2552-2'-O)-methyltransferase | The enzyme catalyses the 2'-O-methylation of the universally conserved U2552 in the A loop of 23S rRNA. Group: Enzymes. Synonyms: Um(2552) 23S ribosomal RNA methyltransferase; heat shock protein RrmJ; RrmJ; FTSJ; Um2552 methyltransferase. Enzyme Commission Number: EC 2.1.1.166. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1763; 23S rRNA (uridine2552-2'-O)-methyltransferase; EC 2.1.1.166; Um(2552) 23S ribosomal RNA methyltransferase; heat shock protein RrmJ; RrmJ; FTSJ; Um2552 methyltransferase. Cat No: EXWM-1763. | |
| 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase | The enzyme is involved in the biosynthesis of the protective and allelophatic benzoxazinoid DIMBOA [(2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin] in some plants, most commonly from the family of Poaceae (grasses). Group: Enzymes. Synonyms: BX7 (gene name); OMT BX7. Enzyme Commission Number: EC 2.1.1.241. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1844; 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase; EC 2.1.1.241; BX7 (gene name); OMT BX7. Cat No: EXWM-1844. | |
| 24-methylenesterol C-methyltransferase | This is the second methylation step of plant sterol biosynthesis (cf EC 2.1.1.142, cycloartenol 24-C-methyltransferase). Group: Enzymes. Synonyms: SMT2; 24-methylenelophenol C-241-methyltransferase. Enzyme Commission Number: EC 2.1.1.143. CAS No. 67165-89-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1739; 24-methylenesterol C-methyltransferase; EC 2.1.1.143; 67165-89-3; SMT2; 24-methylenelophenol C-241-methyltransferase. Cat No: EXWM-1739. | |
| 25S rRNA (adenine2142-N1)-methyltransferase | In the yeast Saccharomyces cerevisiae this methylation is important for resistance towards hydrogen peroxide and the antibiotic anisomycin. Group: Enzymes. Synonyms: BMT2 (gene name); 25S rRNA m1A2142 methyltransferase. Enzyme Commission Number: EC 2.1.1.286. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1893; 25S rRNA (adenine2142-N1)-methyltransferase; EC 2.1.1.286; BMT2 (gene name); 25S rRNA m1A2142 methyltransferase. Cat No: EXWM-1893. | |
| 25S rRNA (adenine645-N1)-methyltransferase | The enzyme is found in eukaryotes. The adenine position refers to rRNA in the yeast Saccharomyces cerevisiae, in which the enzyme is important for ribosome biogenesis. Group: Enzymes. Synonyms: 25S rRNA m1A645 methyltransferase; Rrp8. Enzyme Commission Number: EC 2.1.1.287. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1894; 25S rRNA (adenine645-N1)-methyltransferase; EC 2.1.1.287; 25S rRNA m1A645 methyltransferase; Rrp8. Cat No: EXWM-1894. | |
| 25S rRNA (cytosine2278-C5)-methyltransferase | The enzyme, found in eukaryotes, is specific for 25S cytosine2278. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae. Group: Enzymes. Synonyms: RCM1 (gene name). Enzyme Commission Number: EC 2.1.1.311. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1919; 25S rRNA (cytosine2278-C5)-methyltransferase; EC 2.1.1.311; RCM1 (gene name). Cat No: EXWM-1919. | |
| 25S rRNA (cytosine2870-C5)-methyltransferase | The enzyme, found in eukaryotes, is specific for cytosine2870 of the 25S ribosomal RNA. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae. Group: Enzymes. Synonyms: NOP2 (gene name). Enzyme Commission Number: EC 2.1.1.310. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1918; 25S rRNA (cytosine2870-C5)-methyltransferase; EC 2.1.1.310; NOP2 (gene name). Cat No: EXWM-1918. | |
| 25S rRNA (uracil2634-N3)-methyltransferase | The enzyme, described from the yeast Saccharomyces cerevisiae, is involved in ribosome biogenesis. Group: Enzymes. Synonyms: BMT5. Enzyme Commission Number: EC 2.1.1.313. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1921; 25S rRNA (uracil2634-N3)-methyltransferase; EC 2.1.1.313; BMT5. Cat No: EXWM-1921. | |
| 25S rRNA (uracil2843-N3)-methyltransferase | The enzyme, described from the yeast Saccharomyces cerevisiae, is involved in ribosome biogenesis. Group: Enzymes. Synonyms: BMT6. Enzyme Commission Number: EC 2.1.1.312. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1920; 25S rRNA (uracil2843-N3)-methyltransferase; EC 2.1.1.312; BMT6. Cat No: EXWM-1920. | |
| 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase | Specifically methylates 2,4',7-trihydroxyisoflavanone on the 4'-position. No activity with isoflavones. The enzyme is involved in formononetin biosynthesis in legumes. The protein from pea (Pisum sativum) also methylates (+)-6a-hydroxymaackiain at the 3-position (cf. EC 2.1.1.270, (+)-6a-hydroxymaackiain 3-O-methyltransferase). Group: Enzymes. Synonyms: SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; HI4'OMT; HMM1; MtIOMT5; S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase. Enzyme Commission Number: EC 2.1.1.212. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1814; 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; EC 2.1.1.212; SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; HI4'OMT; HMM1; MtIOMT5; S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase. Cat No: EXWM-1814. | |
| 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | The enzyme from the bacterium Streptomyces carzinostaticus is involved in the biosynthesis of 2-hydroxy-7-methoxy-5-methyl-1-naphthoate. This compound is part of the enediyne chromophore of the antitumor antibiotic neocarzinostatin. In vivo the enzyme catalyses the regiospecific methylation at the 7-hydroxy group of its native substrate 2,7-dihydroxy-5-methyl-1-naphthoate. In vitro it also recognizes other dihydroxynaphthoic acids and catalyses their regiospecific O-methylation. Group: Enzymes. Synonyms: NcsB1; neocarzinostatin O-methyltransferase. Enzyme Commission Number: EC 2.1.1.303. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1911; 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase; EC 2.1.1.303; NcsB1; neocarzinostatin O-methyltransferase. Cat No: EXWM-1911. | |
| 27-O-demethylrifamycin SV methyltransferase | The enzyme, characterized from the bacterium Amycolatopsis mediterranei, is involved in biosynthesis of the antitubercular drug rifamycin B. Group: Enzymes. Synonyms: AdoMet:27-O-demethylrifamycin SV methyltransferase. Enzyme Commission Number: EC 2.1.1.315. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1923; 27-O-demethylrifamycin SV methyltransferase; EC 2.1.1.315; AdoMet:27-O-demethylrifamycin SV methyltransferase. Cat No: EXWM-1923. | |
| 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase | Spb1p is a site-specific 2'-O-ribose RNA methyltransferase that catalyses the formation of 2'-O-methylguanosine2922, a universally conserved position of the catalytic center of the ribosome that is essential for translation. 2'-O-Methylguanosine2922 is formed at a later stage of the processing, during the maturation of of the 27S pre-rRNA. In absence of snR52, Spb1p can also catalyse the formation of uridine2921. Group: Enzymes. Synonyms: Spb1p (gene name); YCL054W (gene name). Enzyme Commission Number: EC 2.1.1.167. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1764; 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase; EC 2.1.1.167; Spb1p (gene name); YCL054W (gene name). Cat No: EXWM-1764. | |
| 2-hydroxyethylphosphonate methyltransferase | Requires cobalamin. The enzyme, isolated from the bacterium Streptomyces wedmorensis, is a member of the 'AdoMet radical' (radical SAM) family. Involved in fosfomycin biosynthesis. Group: Enzymes. Synonyms: Fom3. Enzyme Commission Number: EC 2.1.1.308. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1916; 2-hydroxyethylphosphonate methyltransferase; EC 2.1.1.308; Fom3. Cat No: EXWM-1916. | |
| 2-ketoarginine methyltransferase | The enzyme is involved in production of the rare amino acid 3-methylarginine, which is used by the epiphytic bacterium Pseudomonas syringae pv. syringae as an antibiotic against the related pathogenic species Pseudomonas syringae pv. glycinea. Group: Enzymes. Synonyms: mrsA (gene name). Enzyme Commission Number: EC 2.1.1.243. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1846; 2-ketoarginine methyltransferase; EC 2.1.1.243; mrsA (gene name). Cat No: EXWM-1846. | |
| 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase | Involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols). Group: Enzymes. Synonyms: VTE3 (gene name); 2-methyl-6-solanyl-1,4-hydroquinone methyltransferase; MPBQ/MSBQ methyltransferase; MPBQ/MSBQ MT. Enzyme Commission Number: EC 2.1.1.295. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1902; 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase; EC 2.1.1.295; VTE3 (gene name); 2-methyl-6-solanyl-1,4-hydroquinone methyltransferase; MPBQ/MSBQ methyltransferase; MPBQ/MSBQ MT. Cat No: EXWM-1902. | |
| 3,7-dimethylquercetin 4'-O-methyltransferase | 3,7-Dimethylquercetagetin can also act as acceptor. Involved with EC 2.1.1.76 quercetin 3-O-methyltransferase and EC 2.1.1.82 3-methylquercetin 7-O-methyltransferase in the methylation of quercetin to 3,7,4'-trimethylquercetin in Chrysosplenium americanum. Does not act on flavones, dihydroflavonols, or their glucosides. Group: Enzymes. Synonyms: flavonol 4'-O-methyltransferase; flavonol 4'-methyltransferase; 4'-OMT; S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase; 3,7-dimethylquercitin 4'-O-methyltransferase [mis-spelt]. Enzyme Commission Number: EC 2.1.1.83. CAS No. 96477-60-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1984; 3,7-dimethylquercetin 4'-O-methyltransferase; EC 2.1.1.83; 96477-60-0; flavonol 4'-O-methyltransferase; flavonol 4'-methyltransferase; 4'-OMT; S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase; 3,7-dimethylquercitin 4'-O-methyltransferase [mis-spelt]. Cat No: EXWM-1984. | |
| 3'-demethylstaurosporine O-methyltransferase | Catalyses the final step in the biosynthesis of staurosporine, an alkaloidal antibiotic that is a potent inhibitor of protein kinases, especially protein kinase C. Group: Enzymes. Synonyms: 3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase; staurosporine synthase. Enzyme Commission Number: EC 2.1.1.139. CAS No. 212906-74-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1734; 3'-demethylstaurosporine O-methyltransferase; EC 2.1.1.139; 212906-74-6; 3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase; staurosporine synthase. Cat No: EXWM-1734. | |
| 3-demethylubiquinol 3-O-methyltransferase | This enzyme is involved in ubiquinone biosynthesis. Ubiquinones from different organisms have a different number of prenyl units (for example, ubiquinone-6 in Saccharomyces, ubiquinone-9 in rat and ubiquinone-10 in human), and thus the natural substrate for the enzymes from different organisms has a different number of prenyl units. However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units. For example, the human COQ3 enzyme can restore biosynthesis of ubiquinone-6 in coq3 deletion mutants of yeast.The enzymes from yeast, Escherichia coli and rat also catalyse the methylation of 3,4-dihydroxy-5-all-trans-polyprenylbenzoate (a reac...COQ3 (gene name); Coq3 O-methyltransferase; ubiG (gene name, ambiguous). Enzyme Commission Number: EC 2.1.1.64. CAS No. 63774-48-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1966; 3-demethylubiquinol 3-O-methyltransferase; EC 2.1.1.64; 63774-48-1; 5-demethylubiquinone-9 methyltransferase; OMHMB-methyltransferase; 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase; S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase; COQ3 (gene name); Coq3 O-methyltransferase; ubiG (gene name, ambiguous). Cat No: EXWM-1966. | |
| 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase | Involved in the biosynthesis of vindoline from tabersonine in the Madagascar periwinkleCatharanthus roseus. Group: Enzymes. Synonyms: 16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase; NMT; 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase; S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase. Enzyme Commission Number: EC 2.1.1.99. CAS No. 113478-40-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1999; 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase; EC 2.1.1.99; 113478-40-3; 16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase; NMT; 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase; S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase. Cat No: EXWM-1999. | |
| 3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase | The enzyme from the bacterium Streptomyces sahachiroi is involved in the biosynthesis of 3-methoxy-5-methyl-1-naphthoate, a component of of the the antitumor antibiotic azinomycin B. Group: Enzymes. Synonyms: AziB2. Enzyme Commission Number: EC 2.1.1.302. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1910; 3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase; EC 2.1.1.302; AziB2. Cat No: EXWM-1910. | |
| 3-hydroxyanthranilate 4-C-methyltransferase | Involved in the biosynthesis of the antibiotic actinomycin in Streptomyces antibioticus. Group: Enzymes. Synonyms: 3-hydroxyanthranilate 4-methyltransferase. Enzyme Commission Number: EC 2.1.1.97. CAS No. 112445-22-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1997; 3-hydroxyanthranilate 4-C-methyltransferase; EC 2.1.1.97; 112445-22-4; 3-hydroxyanthranilate 4-methyltransferase. Cat No: EXWM-1997. | |
| 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase | Involved in isoquinoline alkaloid metabolism in plants. The enzyme has also been shown to catalyse the methylation of (RS)-laudanosoline, (S)-3'-hydroxycoclaurine and (RS)-7-O-methylnorlaudanosoline. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.116. CAS No. 132084-81-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1715; 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase; EC 2.1.1.116; 132084-81-2. Cat No: EXWM-1715. | |
| 3-methylquercetin 7-O-methyltransferase | Involved with EC 2.1.1.76 quercetin 3-O-methyltransferase and EC 2.1.1.83 3,7-dimethylquercetin 4'-O-methyltransferase in the methylation of quercetin to 3,7,4'-trimethylquercetin in Chrysosplenium americanum. Does not act on flavones, dihydroflavonols, or their glucosides. Group: Enzymes. Synonyms: flavonol 7-O-methyltransferase; flavonol 7-methyltransferase; 7-OMT; S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase; 3-methylquercitin 7-O-methyltransferase [mis-spelt]. Enzyme Commission Number: EC 2.1.1.82. CAS No. 97089-67-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1983; 3-methylquercetin 7-O-methyltransferase; EC 2.1.1.82; 97089-67-3; flavonol 7-O-methyltransferase; flavonol 7-methyltransferase; 7-OMT; S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase; 3-methylquercitin 7-O-methyltransferase [mis-spelt]. Cat No: EXWM-1983. | |
| 3-O-phospho-polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 3-phospho-methyltransferase | The enzyme is involved in the biosynthesis of the polymannose O-polysaccharide in the outer leaflet of the membrane of Escherichia coli serotype O9a. O-Polysaccharide structures vary extensively because of differences in the number and type of sugars in the repeat unit. The dual kinase/methylase WbdD also catalyses the preceding phosphorylation of α-D-Man-(1?2)-α-D-Man-(1?2)-α-D-Man-(1?3)-α-D-Man-(1?3)-[α-D-Man-(1?2)-α-D-Man-(1?2)-α-D-Man-(1?3)-α-D-Man-(1?3)]n-α-D-Man-(1?3)-α-D-Man-(1?3)-α-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol (cf. EC 2.7.1.181, α-D-Man-(1?2)-α-D-Man-(1?3)-α-D-Man-(1?3)-α-D-Man-diphospho-ditrans,octacis-undecaprenol 3-kinase). Group: Enzymes. Synonyms: WbdD. Enzyme Commission Number: EC 2.1.1.294. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1901; 3-O-phospho-polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 3-phospho-methyltransferase; EC 2.1.1.294; WbdD. Cat No: EXWM-1901. | |
| 4-dimethylallyltryptophan N-methyltransferase | The enzyme catalyses a step in the pathway leading to biosynthesis of ergot alkaloids in certain fungi. Group: Enzymes. Synonyms: fgaMT (gene name); easF (gene name). Enzyme Commission Number: EC 2.1.1.261. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1866; 4-dimethylallyltryptophan N-methyltransferase; EC 2.1.1.261; fgaMT (gene name); easF (gene name). Cat No: EXWM-1866. | |
| 5-hydroxyfuranocoumarin 5-O-methyltransferase | Converts bergaptol into bergapten, which has therapeutic potential in the treatment of psoriasis as it has photosensitizing and antiproliferative activities. The enzyme methylates the 5-hydroxy group of some hydroxy- and methylcoumarins, such as 5-hydroxyxanthotoxin, but has little activity on non-coumarin phenols. Caffeate, 5-hydroxyferulate and daphnetin are not substrates. Cu2+, Zn2+ and Co2+ cause enzyme inhibition. (see also EC 2.1.1.70, 8-hydroxyfuranocoumarin 8-O-methyltransferase). Group: Enzymes. Synonyms: furanocoumarin 5-methyltransferase; furanocoumarin 5-O-methyltransferase; bergaptol 5-O-methyltransferase; bergaptol O-methyltransferase; bergaptol methyltransferase; S-adenosyl-L-methionine:bergaptol O-methyltransferas. Enzyme Commission Number: EC 2.1.1.69. CAS No. 67339-12-2, 101637-31-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1970; 5-hydroxyfuranocoumarin 5-O-methyltransferase; EC 2.1.1.69; 67339-12-2, 101637-31-4; furanocoumarin 5-methyltransferase; furanocoumarin 5-O-methyltransferase; bergaptol 5-O-methyltransferase; bergaptol O-methyltransferase; bergaptol methyltransferase; S-adenosyl-L-methionine:bergaptol O-methyltransferase; BMT; S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5-O-methyltransferase. Cat No: EXWM-1970. | |
| 5-methyltetrahydrofolate: corrinoid/iron-sulfur protein Co-methyltransferase | Catalyses the transfer of a methyl group from the N5 group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein. Involved, together with EC 1.2.7.4, carbon-monoxide dehydrogenase (ferredoxin) and EC 2.3.1.169, CO-methylating acetyl-CoA synthase, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. Group: Enzymes. Synonyms: acsE (gene name). Enzyme Commission Number: EC 2.1.1.258. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1862; 5-methyltetrahydrofolate: corrinoid/iron-sulfur protein Co-methyltransferase; EC 2.1.1.258; acsE (gene name). Cat No: EXWM-1862. | |
| 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase | Requires phosphate and contains zinc. The enzyme from Escherichia coli also requires a reducing system. Unlike EC 2.1.1.13, methionine synthase, this enzyme does not contain cobalamin. Group: Enzymes. Synonyms: tetrahydropteroyltriglutamate methyltransferase; homocysteine methylase; methyltransferase, tetrahydropteroylglutamate-homocysteine transmethylase; methyl tetrahydropteroylpolyglutamate: homocysteine methyltransferase; cobalamin-independent methionine synthase; methionine synthase (cobalamin-independent); MetE. Enzyme Commission Number: EC 2.1.1.14. CAS No. 9068-29-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1735; 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase; EC 2.1.1.14; 9068-29-5; tetrahydropteroyltriglutamate methyltransferase; homocysteine methylase; methyltransferase, tetrahydropteroylglutamate-homocysteine transmethylase; methyl tetrahydropteroylpolyglutamate: homocysteine methyltransferase; cobalamin-independent methionine synthase; methionine synthase (cobalamin-independent); MetE. Cat No: EXWM-1735. | |
| 5-methyltetrahydrosarcinapterin: corrinoid/iron-sulfur protein Co-methyltransferase | Catalyses the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin. Forms, together with EC 1.2.7.4, carbon-monoxide dehydrogenase (ferredoxin) and EC 2.3.1.169, CO-methylating acetyl-CoA synthase, the acetyl-CoA decarbonylase/synthase complex that catalyses the demethylation of acetyl-CoA in a reaction that also forms CO2. This reaction is a key step in methanogenesis from acetate. Group: Enzymes. Synonyms: cdhD (gene name); cdhE (gene name). Enzyme Commission Number: EC 2.1.1.245. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1848; 5-methyltetrahydrosarcinapterin: corrinoid/iron-sulfur protein Co-methyltransferase; EC 2.1.1.245; cdhD (gene name); cdhE (gene name). Cat No: EXWM-1848. | |
| (+)-6a-hydroxymaackiain 3-O-methyltransferase | The protein from the plant Pisum sativum (garden pea) methylates (+)-6a-hydroxymaackiain at the 3-position. It also methylates 2,7,4'-trihydroxyisoflavanone on the 4'-position (cf. EC 2.1.1.212, 2,7,4-trihydroxyisoflavanone 4-O-methyltransferase) with lower activity. Group: Enzymes. Synonyms: HM3OMT; HMM2. Enzyme Commission Number: EC 2.1.1.270. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1876; (+)-6a-hydroxymaackiain 3-O-methyltransferase; EC 2.1.1.270; HM3OMT; HMM2. Cat No: EXWM-1876. | |
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