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Methysergide maleate Methysergide is a prescription drug formerly used for prophylaxis of cluster headaches/migraine headaches, but is no longer recommended due to retroperitoneal/retropulmonary fibrosis. Methysergide maleate is a nonselective 5-HT1, 5-HT2, and 5-HT7 serotonin receptor antagonist. Synonyms: (8β)-9,10-Didehydro-N-[(1S)-1-(hydroxymethyl)propyl]-1,6-dimethyl-ergoline-8-carboxamide (2Z)-2-Butenedioate; [8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethyl-ergoline-8-carboxamide (Z)-2-Butenedioate (1:1); 9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethyl-ergoline-8β-carboxamide Maleate (1:1); N-[1-(Hydroxymethyl)propyl]-1-methyl-lysergamide Maleate; (+)-N-[(1-Hydroxymethyl)propyl]-1-methyl-D-lysergamide Bimaleate; 1-Methyl-D-lysergic Acid Butanolamide Bimaleate; Deseril-retard; Desernil; Desernil Bimaleate; Methysergide Bimaleate; Methysergide Hydrogen Maleate; Methysergide Maleate; NSC 186061; Sansert. Grades: ≥99% by HPLC. CAS No. 129-49-7. Molecular formula: C21H27N3O2.C4H4O4. Mole weight: 469.54. BOC Sciences
Methysergide maleate Methysergide maleate. Group: Biochemicals. Grades: Purified. CAS No. 129-49-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
Methysergide Maleate (5-HT Serotonin Receptor Antagonsit, Methysergide Maleate, UML-491) An antagonist of the 5-HT2B (pki = 8.0-9.4) and 5-HT2C (pki = 8.6-9.1) receptor. At the 5-HT1A and some other 5-HT receptors it serves as a partial agonist. It is known to have partial agonist effects on other 5-HT receptors as well. In neuronal and platelet culture, Methysergide blocks serotonin action with an IC50 = 18uM. Originally developed in the 1960?s as a migraine/cluster headache treatment, but discontinued due to significant physiological and pyschotropic side effects. Methysergide is still actively used in research as a 5-HT2 receptor antagonist in both in vivo and in vitro experiments. Group: Biochemicals. Grades: Highly Purified. CAS No. 129-49-7. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·C?H?O?. US Biological Life Sciences. USBiological 4
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Methysergide dimaleate Heterocyclic Organic Compound. Alternative Names: 1- (hydroxymethyl)propylamideof1-methyl- (+)-lysergicacidhydrogenmaleate; deseril-retard; ergoline-8-beta-carboxamide, 9, 10-didehydro-n- (1- (hydroxymethyl)propyl)-1, 6-dim; maleate (1: 1) (salt); methysergidebimaleate; methysergidedimaleate; methysergidehydrogenmaleat. CAS No. 129-49-7. Molecular formula: C21H27N3O2 C4H4O4. Mole weight: 469.59. Purity: >99 %. Density: 1.28g/cm³. Catalog: ACM129497. Alfa Chemistry. 4
Methyl Ergonovine-d5 Maleate Salt A labeled metabolite of Methysergide. Semisynthetic ergot alkaloid. Oxytocic. Group: Biochemicals. Alternative Names: (8 β)-9,10-Didehydro-N-[(1S)-1-(hydroxymethyl)propyl-d5]-6-methyl-ergoline-8-carbox-amide Maleate; N-[α-(Hydroxymethyl)propyl]-D-lysergamide-d5 Maleate; Basofortina-d5; Erezin-d5; Metenarin-d5; Methergin-d5; Methergine-d5. Grades: Highly Purified. Pack Sizes: 500ug. Molecular Formula: C24H24D5N3O6, Melting Point: >167ºC (dec.). US Biological Life Sciences. USBiological 2
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Methyl Ergonovine Maleate Salt A metabolite of Methysergide. Semisynthetic ergot alkaloid. Oxytocic. Group: Biochemicals. Alternative Names: (8 β)-9,10-Didehydro-N-[(1S)-1-(hydroxymethyl)propyl]-6-methyl-ergoline-8-carbox-amide Maleate; N-[α-(Hydroxymethyl)propyl]-D-lysergamide Maleate; Basofortina; Erezin; Metenarin; Methergin; Methergine; Methylergobasine Maleate; Methylergometrine Maleate. Grades: Highly Purified. CAS No. 57432-61-8. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
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