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| Product | Description | |
|---|---|---|
| Metyrapone | Metyrapone. Group: Biochemicals. Grades: Purified. CAS No. 54-36-4. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Metyrapone | Metyrapone (Su-4885) is a potent and orally active 11β-hydroxylase inhibitor and an autophagy activator, also inhibits the production of aldosterone. Metyrapone inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion. In addition, Metyrapone increases the efficiency of autophagic process via downregulation of mTOR pathway, and interacts with Pseudomonas putida cytochrome P-450. Metyrapone can be used for researching Cushing's syndrome and depression [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Su-4885. CAS No. 54-36-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1232. |  |
| 2-Methyl-1,2-di-3-pyridyl-1-propanone | Metyrapone acts as a glucocorticoid synthesis inhibitor, blocks cortisol synthesis by inhibiting steroid 11β-hydroxylase in adrenal cortex (IC50 = 7.8 μM). Uses: A glucocorticoid synthesis inhibitor. Synonyms: 2-methyl-1,2-dipyridin-3-ylpropan-1-one. Grades: ≥ 98 %. CAS No. 54-36-4. Molecular formula: C14H14N2O. Mole weight: 226.27. |  |
| 2-Methyl-1,2-di-4-pyridinyl-1-propanone | 2-Methyl-1,2-di-4-pyridinyl-1-propanone is an analog of Metyrapone (M338990). Studies show that 2-Methyl-1,2-di-4-pyridinyl-1-propanone induced blockage of 18-hydroxylation in the adrenal cortex of rats which increased the activity in the zona glomerulosa and of the mineralocorticoids. Group: Biochemicals. Grades: Highly Purified. CAS No. 17286-92-9. Pack Sizes: 100mg, 500mg. Molecular Formula: C14H14N2O, Molecular Weight: 226.27. US Biological Life Sciences. | Worldwide |
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