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Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agent, and induces apoptosis , arrests cancer cells in G 0 /G 1 phase. Mevastatin also increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. Mevastatin has antitumor activity and has the potential for cardiovascular diseases treatment [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Compactin; ML236B. CAS No. 73573-88-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-17408.
Mevastatin
Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agent, and induces apoptosis, arrests cancer cells in G0/G1 phase. Mevastatin also increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. Mevastatin has antitumor activity and has the potential for cardiovascular diseases treatment. Group: Inhibitors. CAS No. 73573-88-3. Molecular formula: C23H34O5. Mole weight: 390.51. Appearance: Powder. Purity: 0.98. IUPACName: [(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate. Canonical SMILES: CCC (C)C (=O)OC1CCC=C2C1C (C (C=C2)C)CCC3CC (CC (=O)O3)O. Catalog: ACM73573883.
Mevastatin
Mevastatin. Group: Biochemicals. Grades: Purified. CAS No. 73573-88-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Mevastatin (Compactin)
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C23H34O5. CAS No. 73573-88-3. Prepack ID 58483586-5g. Molecular Weight 390.51. See USA prepack pricing.
Mevastatin (Compactin, Antibiotic ML 236B, ML 236B, SIPI 8915, Antibiotic SIpI 8915)
A fungal metabolite which is a potent inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: Compactin, 6-Demethylvevinolin, CS-500, ML-236 B. Grades: Highly Purified. CAS No. 73573-88-3. Pack Sizes: 100mg. US Biological Life Sciences.
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Mevastatin Hydroxy Acid Sodium Salt
An active carboxylate of Mevastatin. It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood. Group: Biochemicals. Alternative Names: ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Sodium Salt;[1S-[1α( βS*, δS*), 2α, 8 β(R*),8aα]]-1,2,6,7,8,8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid Monosodium Salt; ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Monosodium Salt; ML 236B Sodium Salt. Grades: Highly Purified. CAS No. 99782-89-5. Pack Sizes: 25mg. US Biological Life Sciences.
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Mevastatin Hydroxy Acid t-Butylamine Salt
A HMG-CoA reductase inhibitor. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood. Group: Biochemicals. Alternative Names: ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoate 2-Methyl-2-propanamine. Grades: Highly Purified. CAS No. 262285-80-3. Pack Sizes: 50mg. US Biological Life Sciences.
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Lovastatin EP Impurity A (Mevastatin)
Lovastatin EP Impurity A (Mevastatin). Uses: For analytical and research use. Group: Impurity standards. CAS No. 73573-88-3. Molecular Formula: C23H34O5. Mole Weight: 390.52. Catalog: APB73573883.
3-a-Hydroxy Pravastatin Sodium Salt (3-a-iso-Pravastatin)
A metabolite of Pravastatin, a competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of mevastatin. Group: Biochemicals. Alternative Names: 3-a-iso-Pravastatin. Grades: Highly Purified. CAS No. 81093-43-8. Pack Sizes: 1mg. US Biological Life Sciences.
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Pravastatin Deutertated, Sodium Salt
A stable isotope of Pravastatin, a competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of mevastatin.A representative lot is 86% d3, 13% d2 and 1% d1. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of mevastatin. Group: Biochemicals. Alternative Names: Elisor, Kopostat, Mevalotin, Pravachol, Pravaselect. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
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Pravastatin Sodium Salt
Pravastatin sodium is the sodium salt of pravastatin, a ring- opened member of the statin family. Pravastatin is produced biosynthetically from compactin (mevastatin) by a number of micro-organisms, notablyAbsidia, Cunninghamella, Syncephalastrum, Nocardia or Streptomyces. Typically, statins like compactin, lovastatin and simvastatin possess a b-hydroxy lactone ring which is a pro-drug for the readily ring-opened dihydroxyacid generally regarded as the active HMG-CoA inhibitor. Importantly, the free carboxylic acid enables pravastatin to be freely water soluble within biological pH ranges. Pravastatin is used therapeutically to reduce LDL cholesterol. Group: Biochemicals. Grades: Highly Purified. CAS No. 81131-70-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
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