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| Product | Description | |
|---|---|---|
| Miltefosine | A phospholipid drug with antineoplastic and antiprotozoal / antifungal properties, also acts as an Akt inhibitor, and under investigation as a potential therapy against HIV infection. Used for the treatment of visceral and cutaneous leishmaniasis. Active against metronidazole-resistant and -susceptible strains of Trichomonas vaginalis.1 HePC induces an apoptosis-like cell death in the unicellular protozoan parasite Leishmania donovani, the causative agent of leishmaniasis. Hexadecyl phosphocholine (HePC) is an effective apoptosis inducer. Originally developed as an anticancer drug and has been used for treatment of skin metastases of breast cancer. The anti-tumor activity of HePC has been linked with its capacity to induce apoptosis in numerous tumor cell lines. Due to its amphiphilic behavior, HePC accumulates at the cell membrane, affecting membrane fluidity and triggering the apoptotic cell death. Group: Biochemicals. Alternative Names: 2-[[ (Hexadecyloxy) hydroxyphosphinyl]oxy]-N, N, N-trimethylethanaminium; Hexadecyl phosphocholine; Hexadecyl phosphoryl choline; Miltefosine; Miltex; n-Hexadecyl phosphocholine; 1-Hexadecyl phosphoryl choline; Choline Hexadecyl Phosphate, HePC+. Grades: Reagent Grade. CAS No. 58066-85-6. Pack Sizes: 500mg, 1g, 5g. Molecular Formula: C21H46NO4P, Molecular Weight: 407.57. US Biological Life Sciences. |  Worldwide |
| Miltefosine | Miltefosine inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa, first oral drug for Visceral leishmaniasis, effective against both promastigotes and amastigotes. Uses: Antineoplastic agents. Synonyms: n-hexadecylphosphocholine; Hexadecylphosphocholine; Miltex; Impavido; 2-[[(Hexadecyloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethylethanaminium; MAPCHO®-16; C-16Miltefosine. Grade: >98%. CAS No. 58066-85-6. Molecular formula: C21H46NO4P. Mole weight: 407.57. |  |
| Miltefosine | Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity [1] [2] [3] [4]. Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT) [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HePC; Hexadecyl phosphocholine. CAS No. 58066-85-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-13685. |  |
| 1-O-Nonyl-rac-glycerol | 1-O-Nonyl-rac-glycerol is found to be synergistic with amphotericin B against fungi. It is also a constituent of hexadecyl phosphocholine (miltefosine) as an anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 113676-50-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H26O3, Molecular Weight: 218.33. US Biological Life Sciences. | Worldwide |
| 1-O-Nonyl-rac-glycerol-d5 | 1-O-Nonyl-rac-glycerol-d5 is labelled 1-O-Nonyl-rac-glycerol (N is found to be synergistic with amphotericin B against fungi. It is also a constituent of hexadecyl phosphocholine (miltefosine) as an anticancer agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H21D5O3, Molecular Weight: 223.36. US Biological Life Sciences. | Worldwide |
| 1-O-Propylglycerol | 1-O-Propylglycerol enhances the penetration of anticancer agents through the blood-brain barrier (BBB). It is also a constituent of hexadecyl phosphocholine (miltefosine) as an anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 61940-71-4. Pack Sizes: 500mg, 1g. Molecular Formula: C6H14O3. US Biological Life Sciences. | Worldwide |
| 1-O-Propylglycerol-d5 | 1-O-Propylglycerol-d5 is labelled 1-O-Propylglycerol (P837050) which enhances the penetration of anticancer agents through the blood-brain barrier (BBB). It is also a constituent of hexadecyl phosphocholine (miltefosine) as an anticancer agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C6H9D5O3, Molecular Weight: 139.199999999999. US Biological Life Sciences. | Worldwide |
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