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| Product | Description | |
|---|---|---|
| Mitoguazone | Mitoguazone is a guanylhydrazone with potential antineoplastic activity. Mitoguazone competitively inhibits S-adenosyl-L-methionine decarboxylase (SAMD), an enzyme involved in the synthesis of polyamines, resulting in decreased proliferation of tumor cells, antimitochondrial effects, and p53-independent apoptosis. Polyamines, specifically spermine and spermidine, are essential for thymidine kinase production, DNA synthesis, and cell proliferation. Synonyms: MeGAG; methyl-G; methyl-GAG; MGBG; MGGH; DRG-0223; DRG 0223; DRG0223; NSC32946; NSC 32946; NSC-32946. Grades: 99.38%. CAS No. 459-86-9. Molecular formula: C5H12N8. Mole weight: 184.21. |  |
| Mitoguazone | Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG. CAS No. 459-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-106634. |  |
| Mitoguazone dihydrochloride monohydrate | Mitoguazone dihydrochloride monohydrate (CAS# 332360-02-8 ) is a useful research chemical. Synonyms: Methylglyoxal bis(guanylhydrazone) hydrate dihydrochloride; 2,2'-(1-Methyl-1,2-ethanediylidene) bis(hydrazinecarboximidamide) dihydrochloride hydrate; Methylglyoxal bis(guanylhydrazone) dihydrochloride hydrate; Methyl GAG dihydrochloride monohydrate; Methylglyoxal bis(guanylhydrazone) dihydrochloride monohydrate; 2,2'-(Propane-1,2-diylidene)di(hydrazine-1-carboximidamide)-hydrogen chloride-water. CAS No. 332360-02-8. Molecular formula: C5H16Cl2N8O. Mole weight: 275.14. | |
| 3,3'-(1-Methylethane-1,2-diylidene)dicarbazamidine dihydrochloride | 3,3'-(1-Methylethane-1,2-diylidene)dicarbazamidine dihydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Guanylhydrazone, Methyl-Gag, Methyl-G, Methyl GAG, MGBG, MGGH, MITOGUAZONE, NSC32946, NSC69432, CID5351153, Methylglyoxal bis(guanylhydrazone) dihydrochloride, Methylglyoxal bis(guanylhydrazone)dihydrochloride, Methyl glyoxal bis(amidinohydrazone) dihydrochloride, Guanidine, 1,1-methylethanediylidenedinitrilo)di-, dihydrochloride, 7059-23-6, Guanidine, 1,1-[(methylethanediylidene)dinitrilo]di-, dihydrochloride, Guanidine, 1,1-[(methylethanediylidene)dinitrilo]di-, dihydrochloride, monohydrate, Hydrazinecarboximidamide, 2,2-(1-methyl-1,2-ethanediylidene)bis-, dihydrochloride. Product Category: Heterocyclic Organic Compound. CAS No. 7059-23-6. Molecular formula: C5H12N8.2HCl. Mole weight: 219.655380 [g/mol]. Purity: 0.96. IUPACName: 2-[(E)-[(1E)-1-(diaminomethylidenehydrazinylidene)propan-2-ylidene]amino]guanidine chloride. Product ID: ACM7059236. Alfa Chemistry ISO 9001:2015 Certified. |  |
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