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Mitotane (2,4-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,4-DDD; o,p'-DDD. CAS No. 53-19-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-13690.
Mitotane
Mitotane. Group: Biochemicals. Grades: Highly Purified. CAS No. 53-19-0. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C14H10Cl4. US Biological Life Sciences.
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Mitotane
Mitotane, is an antineoplastic medication used in the treatment of adrenocortical carcinoma. Uses: Antineoplastic agents, hormonal. Synonyms: NCI-C04933; NCI C04933; NCIC04933. Grades: >98%. CAS No. 53-19-0. Molecular formula: C14H10Cl4. Mole weight: 320.04.
An Antineoplastic. Used as an adrenolytic agent. Group: Biochemicals. Alternative Names: o,p'-DDD, CB-313, Lysodren,1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Mitotan
Mitotan. Uses: For analytical and research use. Group: Impurity standards. CAS No. 53-19-0. Molecular Formula: C14H10Cl4. Mole Weight: 320.03. Catalog: APB53190.
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