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| Product | Description | |
|---|---|---|
| MK 886 | MK 886. Group: Biochemicals. Grades: Purified. CAS No. 118414-82-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| MK 886 Sodium Salt (3-(1-(4-chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid, L 663536, L-663536, MK-886) | MK 886 Sodium Salt (3-(1-(4-chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid, L 663536, L-663536, MK-886). Group: Biochemicals. Alternative Names: Sodium;3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoate. Grades: Highly Purified. CAS No. 118427-55-7. Pack Sizes: 25mg. Molecular Formula: C27 H33 ClNO 2 , Molecular Weight: 494.1. US Biological Life Sciences. | Worldwide |
| MKC-8866 | MKC-8866, also known as IRE1-IN-8866, is an inhibitor of IRE1 RNase activity. MKC8866 strongly inhibits prostate cancer (PCa) tumor growth as monotherapy in multiple preclinical models in mice and shows synergistic antitumor effects with current PCa drugs. Interestingly, global transcriptomic analysis reveal that IRE1α-XBP1s pathway activity is required for c-MYC signaling, one of the most highly activated oncogenic pathways in PCa. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MKC-8866; MKC 8866; MKC8866; IRE1-IN-8866; IRE1IN8866; IRE1 IN 8866; IRE1-IN8866; IRE1-IN 8866; IRE1IN-8866; IRE1IN 8866. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1338934-59-0. Molecular formula: C18H19NO7. Mole weight: 361.35. Purity: >98%. IUPACName: 7-Hydroxy-6-methoxy-4-methyl-3-(2-morpholino-2-oxoethyl)-2-oxo-2H-chromene-8-carbaldehyde. Canonical SMILES: O=CC1=C(O)C(OC)=CC2=C1OC(C(CC(N3CCOCC3)=O)=C2C)=O. Product ID: ACM1338934590. Alfa Chemistry ISO 9001:2015 Certified. |  |
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