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MK-2048 MK-2048 is a second generation integrase inhibitor (IC50=2.6 nM). It can inhibits the HIV enzyme integrase 4 times longer than raltegravir. Synonyms: MK2048; MK 2048; MK-2048. Grades: >98%. CAS No. 869901-69-9. Molecular formula: C22H24FN5O4. Mole weight: 441.46. BOC Sciences 10
MK-2048 MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir. MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir. Group: Biochemicals. Alternative Names: (6S)-2-(3-Chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N, 6-dimethyl-1, 9-dioxo-1, 2, 6, 7, 8, 9-hexahydropyrazino[1', 2':1, 5]pyrrolo[2, 3-d]pyridazine-4-carboxamide. Grades: Highly Purified. CAS No. 869901-69-9. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
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