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| Product | Description | |
|---|---|---|
| MK-571 | A receptor antagonist for the treatment of respiratory diseases. Cysteinyl leukotriene receptor antagonist MK-571 alters bronchoalveolar lavage fluid proteome in asthma. Group: Biochemicals. Alternative Names: 3- [ [ [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] [ [3- (dimethylamino) -3-oxopropyl] thio] methyl] thio] propanoic Acid. Grades: Highly Purified. CAS No. 115104-28-4. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| MK-571 | MK-571 (L-660711) is an orally active, potent and selective competitive leukotriene D 4 (LTD 4 ) receptor antagonist, with K i values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 is also a MRP4 and ABCC1 (MRP1) inhibitor. MK-571 inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-660711. CAS No. 115104-28-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19989. |  |
| MK-571 Methyl Ester | Precursor to MK-571. Group: Biochemicals. Alternative Names: 3- [ [ [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] [ [3- (dimethylamino) -3-oxopropyl] thio] methyl] thio] propanoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 120443-15-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MK-571 sodium | MK-571 (L-660711) sodium is an orally active, potent and selective competitive leukotriene D 4 (LTD 4 ) receptor antagonist, with K i values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 sodium is also a inhibitor of multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1). MK-571 sodium inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-660711 sodium. CAS No. 115103-85-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19989A. | |
| MK-571 sodium salt | Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor. Antinociceptive. Group: Biochemicals. Grades: Highly Purified. CAS No. 115104-28-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C26H26ClN2O3S2?Na. US Biological Life Sciences. | Worldwide |
| MK-571 sodium salt | The sodium salt hydrate of MK-571 which is an effective antagonist of CysLT1 receptor and an inhibitor of MRP1. Uses: Bronchodilator agents. Synonyms: sodium (E) -3- ( ( (3- (2- (7-chloroquinolin-2-yl) vinyl) phenyl) ( (3- (dimethylamino) -3-oxopropyl) thio) methyl) thio) propanoate; MK-571; MK 571; MK571; MK-571 sodium salt; L-660,711; L660,711; L 660,711; L-660711; L660711; L 660711. Grades: 95%. CAS No. 115103-85-0. Molecular formula: C26H26ClN2NaO3S2. Mole weight: 537.07. |  |
| MK-571 sodium salt hydrate | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| 3, 3'- [ [ [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] methylene] bis (thio) ] bis-propanoic Acid 1,1'-Dimethyl Ester | Intermediate in the preparation of MK-571. Group: Biochemicals. Alternative Names: (E) -3, 3'- [ [ [3- [2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] methylene] bis (thio) ] bis-propanoic Acid Dimethyl Ester. Grades: Highly Purified. CAS No. 120385-96-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| (E) -3- [ [ [ (2-Carboxyethyl) thio] [3- [2- (7-chloro-2-quinolinyl) ethenyl] phenyl] methyl] thio] propanoic Acid 1-Methyl Ester | Intermediate in the preparation of MK-571. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MK 571 | MK-571 is a CysLT1 receptor antagonist. It can be used for the treatment of respiratory diseases. Uses: Leukotriene antagonists. Synonyms: MK 571; MK571; MK-571; 3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid. Grades: ≥98% by HPLC. CAS No. 115104-28-4. Molecular formula: C26H27ClN2O3S2. Mole weight: 515.09. | |
| Verlukast | This active molecular is a R-enantiomer of MK-571 which is a selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig with IC50 value of 3.1+/-0.5nM, in human lung homogenates with IC50 value of 8.0+/-3.0nM and in dimethyl sulfoxide differentiated U937 cell membrane preparations with IC50 value of 10.7+/-1.6nM. Verlukast was in clinical development for the treatment of respiratory diseases but was discontinued for treatment of Asthma. Uses: The treatment of respiratory diseases. Synonyms: 3-[[(R)-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-propanoic Acid; L 668,019; L 668019; L-668,019; MK 0679; MK 679; MK-679; R-(-)-MK 571. Grades: 95%. CAS No. 120443-16-5. Molecular formula: C26H27ClN2O3S2. Mole weight: 515.09. | |
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