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| Product | Description | |
|---|---|---|
| MK-8722 | MK-8722 is a potent pan-AMPK activator. MK-8722 improves glucose homeostasis but induces cardiac hypertrophy. In rodents and rhesus monkeys, MK-8722-mediated AMPK activation in skeletal muscle induced robust, durable, insulin-independent glucose uptake and glycogen synthesis, with resultant improvements in glycemia and no evidence of hypoglycemia. These effects translated across species, including diabetic rhesus monkeys, but manifested with concomitant cardiac hypertrophy and increased cardiac glycogen without apparent functional sequelae. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MK-8722; MK 8722; MK8722. Product Category: Activators. Appearance: Solid powder. CAS No. 1394371-71-1. Molecular formula: C24H20ClN3O4. Mole weight: 449.89. Purity: >98%. IUPACName: (3R,3aR,6R,6aR)-6-((6-([1,1'-biphenyl]-4-yl)-7-chloro-3H-imidazo[4,5-b]pyridin-2-yl)oxy)hexahydrofuro[3,2-b]furan-3-ol. Canonical SMILES: ClC1=C2C(NC(O[C@@H]3CO[C@@]4([H])[C@]3([H])OC[C@H]4O)=N2)=NC=C1C5=CC=C(C6=CC=CC=C6)C=C5. Product ID: ACM1394371711. Alfa Chemistry ISO 9001:2015 Certified. |  |
| MK-8722 | MK-8722 is a potent pan-AMPK activator that improves glucose homeostasis but induces cardiac hypertrophy. AMPK has long been of interest as a target for the treatment of Type 2 Diabetes Mellitus. Synonyms: MK 8722; MK8722. CAS No. 1394371-71-1. Molecular formula: C24H20ClN3O4. Mole weight: 449.9. |  |
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