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Inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 muM for the inhibition of platelet P-selectin expression on human platelets). Thought to act allosterically. Also inhibits thrombin-induced platelet activation. Synonyms: ML-161; ML161; Parmodulin 2; 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide. CAS No. 423735-93-7. Molecular formula: C17H17BrN2O2. Mole weight: 361.24.
ML 161
ML 161 is a diaminobenzene derivative that acts as a selective inhibitor of platelet activation at protease-activated receptor 1 (PAR1). ML 161 has also been shown to inhibit thrombin-induced platelet activation. Group: Biochemicals. Alternative Names: ML161; 2-Bromo-N- [3- [ (1-oxobutyl) amino] phenyl] benzamide. Grades: Highly Purified. CAS No. 423735-93-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
1-Aminobenzotriazole
1-Aminobenzotriazole is a nonspecific and irreversible inhibitor of cytochrome P450 ( P450 ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT; 3-Aminobenzotriazole. CAS No. 1614-12-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-103389.
2,4-Dihydro-4-phenyl-3H-1,2,4-triazol-3-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NCIOpen2_001519, MLS000736464, NSC93434, MolPort-001-758-655, CID261419, SMR000338414, 5N-071, 4-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-one, 1008-30-6. Product Category: Heterocyclic Organic Compound. CAS No. 1008-30-6. Molecular formula: C8H7N3O. Mole weight: 161.16. Purity: 0.96. IUPACName: 4-phenyl-1H-1,2,4-triazol-5-one. Density: 1.32g/cm³. Product ID: ACM1008306. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one.
2-Thiazolamine,4-[1,1'-biphenyl]-4-yl-
2-Thiazolamine,4-[1,1'-biphenyl]-4-yl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Amino-4-(4-biphenylyl)thiazole, USAF EK-4373, Oprea1_161040, CBDivE_012410, MLS001017970, Thiazole, 2-amino-4-(4-biphenylyl)-, ALBB-000396, BRN 0187642, ZINC02455287, SMR000354210, LS-150774, 4-(1,1-biphenyl-4-yl)-1,3-thiazol-2-amine, 4-27-00-05067 (Beilstein Handbook Reference), A0927/0043411, 2834-79-9. Product Category: Heterocyclic Organic Compound. CAS No. 2834-79-9. Molecular formula: C15H12N2S. Mole weight: 252.3342. Purity: 0.98. IUPACName: 4-(4-phenylphenyl)-1,3-thiazol-2-amine. Canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C3=CSC(=N3)N. Density: 1.23 g/cm³. Product ID: ACM2834799. Alfa Chemistry ISO 9001:2015 Certified.
4-Chlorocinnamic acid
4-Chlorocinnamic acid has inhibitory effects on tyrosinase. 4-Chlorocinnamic acid has antibacterial activity. 4-Chlorocinnamic acid also inhibits Colletotrichum gloeosporioides growth [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1615-02-7. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-Y0729.
Acivicin hydrochloride
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus , is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: AT-125 hydrochloride; U-42126 hydrochloride. CAS No. 161922-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W016586A.
Alofanib
Alofanib (RPT835) is a potent and selective allosteric inhibitor of fibroblast growth factor receptor 2 ( FGFR2 ). Anticancer and antiangiogenic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RPT835. CAS No. 1612888-66-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17601.
Amentoflavone
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Didemethyl-ginkgetin. CAS No. 1617-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0662.
Amotosalen hydrochloride
Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-59. CAS No. 161262-45-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107004A.
Amprenavir
Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.09 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-478. CAS No. 161814-49-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17430.
ARN-3236
ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2) , with IC 50 s of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively. Has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613710-01-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120856.
BAR502
BAR502 is a dual FXR and GPBAR1 agonist with IC 50 values of 2 μM and 0.4 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1612191-86-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101273.
Benzamil hydrochloride
Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na + /Ca 2+ exchanger (NCX) inhibitor ( IC 50 ~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca 2+ -activated currents, with an IC 50 of 1.1 μM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Benzylamiloride hydrochloride. CAS No. 161804-20-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1546A.
Bezuclastinib
Bezuclastinib (CGT9486) is an orally active, highly selective tyrosine kinase inhibitor with potent activity against KIT D816V. Bezuclastinib can be used for the research of nonadvanced systemic mastocytosis (NonAdvSM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGT9486; PLX 9486. CAS No. 1616385-51-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145557.
Bictegravir
Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC 50 of 7.5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9883. CAS No. 1611493-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17605.
CAL-130 Hydrochloride
CAL-130 is a PI3Kδ and PI3Kγ inhibitor with IC 50 s of 1.3 and 6.1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1431697-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16122B.
Celgosivir hydrochloride
Celgosivir hydrochloride (MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC 50 of 1.27 μM in in vitro assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride. CAS No. 141117-12-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16134A.
Cholesterol 24-hydroxylase-IN-1
Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor ( IC 50 =8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613480-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144309.
Cromolyn
Cromolyn is a mast cell stabilizer. Cromolyn has the potential for the research of bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cromoglicic acid. CAS No. 16110-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1619.
Deltarasin hydrochloride
Deltarasin hydrochloride is an inhibitor of KRAS-PDEδ interaction with K d of 38 nM for binding to purified PDE&delta. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613404-76-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15747A.
Desidustat
Desidustat is an orally active HIF hydroxylase inhibitor. Desidustat can be used for the research of various disorders including anemia of different types and conditions associated with ischemia/hypoxia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZYAN1. CAS No. 1616690-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103227.
(-)-Enitociclib
(-)-Enitociclib ((R)-Enitociclib) is an enanthiomer of BAY-1251152 with rotation (-). BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Enitociclib; (-)-BAY-1251152; (-)-VIP152. CAS No. 1610358-59-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-103019B.
(+)-Enitociclib
(+)-Enitociclib ((+)-BAY-1251152) is an enanthiomer of BAY-1251152 with rotation (+). Enitociclib is a potent and selective CDK9 inhibitor with an IC 50 of 3 nM. Enitociclib has anti-tumour activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-BAY-1251152; (+)-VIP152; (S)-Enitociclib. CAS No. 1610358-56-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-103019.
(±)-Enitociclib
(±)-Enitociclib ((±)-BAY-1251152) is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. BAY-1251152 can be used in the study of acute myelogenous leukemia and double-hit diffuse large B-cell lymphoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-BAY-1251152; (±)-VIP152. CAS No. 1610358-53-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103019A.
Esomeprazole magnesium
Esomeprazole magnesium ((S)-Omeprazole magnesium) is a potent and orally active H + , K + -ATPase inhibitor. Esomeprazole magnesium has the potential for upper intestinal disorders and gastroesophageal reflux disease research [1] [2]. Esomeprazole magnesium acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H + -ATPases [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Omeprazole magnesium; (-)-Omeprazole magnesium. CAS No. 161973-10-0. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B1446.
Etalocib
Etalocib (LY293111), an orally active leukotriene B 4 receptor antagonist, inhibits the binding of [ 3 H]LTB 4 , with a K i of 25 nM. Etalocib (LY293111) prevents LTB 4 -induced calcium mobilization with an lC 50 of 20 nM. Etalocib (LY293111) induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY293111; VML 295. CAS No. 161172-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13628.
GSK3326595
GSK3326595 is a protein arginine methyltransferase 5 ( PRMT5 ) inhibitor. GSK3326595 decreases SARS-CoV-2 infection, inhibits cancer cell proliferation and induces pro-inflammatory macrophage polarization and increases hepatic triglyceride levels without affecting atherosclerosis. GSK3326595 can be used for research of relapsed/refractory mantle cell lymphoma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EPZ015938. CAS No. 1616392-22-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-101563.
Heptamidine dimethanesulfonate
Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B ( K d =6.9 μM), selectively kills melanoma cells with S100B over those without S100B [1]. Heptamidine is a useful tool for the investigation of Myotonic dystrophy (DM) [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SBi4211 dimethanesulfonate. CAS No. 161374-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16918A.
Hexamethyldisilazane (HMDS)
500ml Pack Size. Group: Building Blocks, Organics, Stains & Indicators. Formula: C6H19NSi2. CAS No. 999-97-3. Prepack ID 21242140-500ml. Molecular Weight 161.39. See USA prepack pricing.
Isobutylmagnesium bromide, 2M solution in diethyl ether
100ml Pack Size. Group: Analytical Reagents, Building Blocks, Catalysts, Grignard Reagents, Organics. Formula: C4H9BrMg. CAS No. 926-62-5. Prepack ID 90028790-100ml. Molecular Weight 161.32. See USA prepack pricing.
Linsidomine hydrochloride
SIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation [1]. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SIN-1 chloride. CAS No. 16142-27-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101200.
L-Methioninamide hydrochloride
L-Methioninamide hydrochloride, a Methionine analogue, is Methionyl-tRNA synthetase inhibitor [1]. Uses: Scientific research. Group: Peptides. CAS No. 16120-92-6. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W016256.
Methoxyfenozide
Methoxyfenozide, a diacylhydrazine insecticide, selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with K d values of 0.5 and 124 nM, respectively. Methoxyfenozide is lethal to neonatal larvae of S. exigua , S. frugiperda , T. ni , O. nubilalis , L. pomonella , H. zea , and H. virescens (LC 50 s=0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively). Uses: Scientific research. Group: Signaling pathways. CAS No. 161050-58-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-117386.
ML318
ML318 is a novel inhibitor of Pseudomonas aeruginosa PvdQ acylase, an enzyme involved in siderophore pyoverdine synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1610516-67-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C14H8F4N2, Molecular Weight: 280.22. US Biological Life Sciences.
Worldwide
ML-336
ML-336 is a quinazolinone-based inhibitor of Venezuelan Equine Encephalitis Virus (VEEV). It inhibits VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and Trinidad donkey). Synonyms: ML 336; ML336; (E)-2-((1,4-dimethylpiperazin-2-ylidene)-amino)-5-nitro-n-phenylbenzamide. Grades: ≥95%. CAS No. 1613465-33-0. Molecular formula: C19H21N5O3. Mole weight: 367.4.
MT-1207
MT-1207 is an orally active and selective adrenergic α 1 and 5-HT 2A receptor antagonist. MT-1207 shows IC 50 <0.1 nM, 0.15 nM, 1.40 nM and 0.27 nM for α 1A , α 1B , α 1D and 5-HT 2A , respectively. MT-1207 achieves an effective blood pressure (BP) reduction in the 2K2C rat model without damaging renal function. MT-1207 is a potent multitarget inhibitor with the potential for vasodilatation research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1610794-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162677.
N-Desmethylolanzapine
N-Desmethylolanzapine is an antipsychotic drug. The formation of N-Desmethylolanzapine correlates with the level and activity of human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapine can be used in the study of antipsychotic drugs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Demethylolanzapine; LY170055. CAS No. 161696-76-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W009247.
Netoglitazone
Netoglitazone is a dual agonist of PPARα and PPARγ with antihyperglycemic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCC-555; Isaglitazone. CAS No. 161600-01-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100428.
Ozanimod hydrochloride
Ozanimod (RPC-1063) hydrochloride, a sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity selectively to S1P receptor subtypes 1 (S1P1) and 5 (S1P5). Ozanimod hydrochloride has modulate effect for hS1P 1 and hS1P 5 receptor with EC 50 s of 1.03 nM and 8.6 nM, respectively. Ozanimod hydrochloride can be used for the research of relapsing multiple sclerosis (MS) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RPC-1063 hydrochloride. CAS No. 1618636-37-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12288A.
Pelcitoclax
Pelcitoclax (APG-1252) is a potent Bcl-2/Bcl-xl inhibitor with antineoplastic and pro-apoptotic effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APG-1252. CAS No. 1619923-36-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109185.
PF-06372865
PF-06372865 is an orally active, α2/α3/α5 subtype-selective GABA A positive allosteric modulator (PAM). PF-06372865 is a high affinity ligand at GABA A receptors containing α1/α2/α3/α5 subunits ( K i s of 2.9 nM, 21 nM, 134 nM for α2, α1 PAM, α2 PAM, respectively), with low affinity for α4/α6 subunits. PF-06372865 can across the blood-brain barrier (BBB). PF-06372865 has anxiolytic activity and has the potential for epilepsy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1614245-70-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120874.
PF-06726304
PF-06726304 is a potent and selective EZH2 inhibitor. PF-06726304 inhibits wild-type and Y641N mutant EZH2 with K i s of 0.7 and 3.0 nM, respectively. PF-06726304 displays robust antitumor growth activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1616287-82-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103682.
Plozalizumab
Plozalizumab (MLN-1202) is a specific humanized anti- CCR2 antibody. Plozalizumab can be used for malignant melanoma research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MLN-1202. CAS No. 1610761-46-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99781.
Pregnanediol
Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 1612; NSC 47462. CAS No. 80-92-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107850.
Rasagiline mesylate
Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase ( MAO ) inhibitor with IC 50 s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively [1]. Rasagiline (mesylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-AGN1135 mesylate; TVP1012 mesylate. CAS No. 161735-79-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14605.
Seralutinib (GB002) is an inhaled PDGFRα and PDGFRβ inhibitor. Seralutinib also targets to CSF1R and c-KIT with IC 50 s of 8 nM and 14 nM, respectively. Seralutinib (GB002) is used in the study for pulmonary arterial hypertension [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GB002; PK10571. CAS No. 1619931-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109190.
Seviteronel
Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC 50 =69 nM) and an AR antagonist. Seviteronel demonstrates both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VT-464. CAS No. 1610537-15-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15996.
Talampanel
Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity [1]. Talampanel (IVAX) has neuroprotective effects in rodent stroke models [2]. Talampanel attenuates caspase-3 dependent apoptosis in mouse brain [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GYKI-53773; LY-300164. CAS No. 161832-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15079.
Tebipenem
Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LJC 11036. CAS No. 161715-21-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0076.
Tebipenem pivoxil
Tebipenem pivoxil (L084) is an orally active antibiotic against a variety of pathogenic bacteria. Tebipenem pivoxil binds penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L084. CAS No. 161715-24-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0396.
Telomerase-IN-2
Telomerase-IN-2 is a telomerase inhibitor, and inhibits telomerase activity by decreasing expression of dyskerin, with an IC 50 of 0.89?μM. Anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1610878-54-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126482.
Tucidinostat
Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I ( HDAC1/2/3 ) and class IIb ( HDAC10 ) inhibitor, with IC 50 s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 ( IC 50 s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Chidamide; HBI-8000; CS 055. CAS No. 1616493-44-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109015.
Tuvusertib
Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor extracted from patent WO2015187451A1, compound I-l, with a K i value below 1 μΜ [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M1774; ATR inhibitor 1. CAS No. 1613200-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111451.
Unesbulin
Unesbulin (PTC596) is an orally active and selective B-cell-specific Moloney murine leukemia virus integration site 1 ( BMI-1 ) inhibitor. Unesbulin downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia (AML) cells. Unesbulin has anti-leukemic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTC596. CAS No. 1610964-64-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112041.
Vincamine
Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation [1]. Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo , and has the potential for the type 2 diabetes mellitus (T2DM) research [2]. Uses: Scientific research. Group: Natural products. CAS No. 1617-90-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1021.
Sodium Chromate, 0.1 M, Aqueous, Laboratory Grade, 500 mL
Formula: Na2CrO4. Formula Wt: 161. 97. Storage Code: Blue; toxic. Grades: chem-grade laboratory. CAS No. 7775-11-3. Product ID: 889022. -- SOLD FOR EDUCATIONAL USE ONLY --
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