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| Product | Description | |
|---|---|---|
| ML 161 | Inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 muM for the inhibition of platelet P-selectin expression on human platelets). Thought to act allosterically. Also inhibits thrombin-induced platelet activation. Synonyms: ML-161; ML161; Parmodulin 2; 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide. CAS No. 423735-93-7. Molecular formula: C17H17BrN2O2. Mole weight: 361.24. |  |
| ML 161 | ML 161 is a diaminobenzene derivative that acts as a selective inhibitor of platelet activation at protease-activated receptor 1 (PAR1). ML 161 has also been shown to inhibit thrombin-induced platelet activation. Group: Biochemicals. Alternative Names: ML161; 2-Bromo-N- [3- [ (1-oxobutyl) amino] phenyl] benzamide. Grades: Highly Purified. CAS No. 423735-93-7. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| 1-Aminobenzotriazole | 1-Aminobenzotriazole is a nonspecific and irreversible inhibitor of cytochrome P450 ( P450 ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT; 3-Aminobenzotriazole. CAS No. 1614-12-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-103389. |  |
| 2-(2-Pyridyl)thiophene | 2-(2-Pyridyl)thiophene. Group: Electroluminescence materials. Alternative Names: 2-(2-Thienyl)pyridine, 2-thiophen-2-yl-pyridine, MLS000861939, Pyridine, 2-(2-thienyl)-, EINECS 222-022-1, ZINC00105143, SMR000460723, ST5407898, SR-01000635085-1, 3319-99-1. CAS No. 3319-99-1. Product ID: 2-thiophen-2-ylpyridine. Molecular formula: 161.22. Mole weight: C9H7NS. QLPKTAFPRRIFQX-UHFFFAOYSA-N. 96%. |  |
| 2,4-Dihydro-4-phenyl-3H-1,2,4-triazol-3-one | 2,4-Dihydro-4-phenyl-3H-1,2,4-triazol-3-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NCIOpen2_001519, MLS000736464, NSC93434, MolPort-001-758-655, CID261419, SMR000338414, 5N-071, 4-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-one, 1008-30-6. Product Category: Heterocyclic Organic Compound. CAS No. 1008-30-6. Molecular formula: C8H7N3O. Mole weight: 161.16. Purity: 0.96. IUPACName: 4-phenyl-1H-1,2,4-triazol-5-one. Density: 1.32g/cm³. Product ID: ACM1008306. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one. |  |
| 2-Thiazolamine,4-[1,1'-biphenyl]-4-yl- | 2-Thiazolamine,4-[1,1'-biphenyl]-4-yl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Amino-4-(4-biphenylyl)thiazole, USAF EK-4373, Oprea1_161040, CBDivE_012410, MLS001017970, Thiazole, 2-amino-4-(4-biphenylyl)-, ALBB-000396, BRN 0187642, ZINC02455287, SMR000354210, LS-150774, 4-(1,1-biphenyl-4-yl)-1,3-thiazol-2-amine, 4-27-00-05067 (Beilstein Handbook Reference), A0927/0043411, 2834-79-9. Product Category: Heterocyclic Organic Compound. CAS No. 2834-79-9. Molecular formula: C15H12N2S. Mole weight: 252.3342. Purity: 0.98. IUPACName: 4-(4-phenylphenyl)-1,3-thiazol-2-amine. Canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C3=CSC(=N3)N. Density: 1.23 g/cm³. Product ID: ACM2834799. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-Chlorocinnamic acid | 4-Chlorocinnamic acid has inhibitory effects on tyrosinase. 4-Chlorocinnamic acid has antibacterial activity. 4-Chlorocinnamic acid also inhibits Colletotrichum gloeosporioides growth [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1615-02-7. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-Y0729. | |
| Acivicin hydrochloride | Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus , is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: AT-125 hydrochloride; U-42126 hydrochloride. CAS No. 161922-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W016586A. | |
| Alofanib | Alofanib (RPT835) is a potent and selective allosteric inhibitor of fibroblast growth factor receptor 2 ( FGFR2 ). Anticancer and antiangiogenic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RPT835. CAS No. 1612888-66-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17601. | |
| Amentoflavone | Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Didemethyl-ginkgetin. CAS No. 1617-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0662. | |
| Amotosalen hydrochloride | Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-59. CAS No. 161262-45-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107004A. | |
| Amprenavir | Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.09 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-478. CAS No. 161814-49-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17430. | |
| ARN-3236 | ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2) , with IC 50 s of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively. Has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613710-01-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120856. | |
| BAR502 | BAR502 is a dual FXR and GPBAR1 agonist with IC 50 values of 2 μM and 0.4 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1612191-86-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101273. | |
| Benzamil hydrochloride | Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na + /Ca 2+ exchanger (NCX) inhibitor ( IC 50 ~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca 2+ -activated currents, with an IC 50 of 1.1 μM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Benzylamiloride hydrochloride. CAS No. 161804-20-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1546A. | |
| Bezuclastinib | Bezuclastinib (CGT9486) is an orally active, highly selective tyrosine kinase inhibitor with potent activity against KIT D816V. Bezuclastinib can be used for the research of nonadvanced systemic mastocytosis (NonAdvSM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGT9486; PLX 9486. CAS No. 1616385-51-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145557. | |
| Bictegravir | Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC 50 of 7.5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9883. CAS No. 1611493-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17605. | |
| BM-1244 | BM-1244 (APG-1252-M1) is a Bcl-xL/Bcl-2 inhibitor with Kis of 134 nM and 450 nM. BM-1244 has anti-tumor effects by inducing apoptosis and suppressing tumor growth. BM-1244 can induce cytochrome C and Smac release from mitochondria with caspase-3 and PARP cleavage. BM-1244 exhibits synergy with chemotherapy in vivo. BM-1244 can be studied in research for colorectal cancer, acute myeloid leukemia and gastric cancer[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APG-1252-M1. CAS No. 1619923-32-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-138832. | |
| Bromosporine | Bromosporine is a potent BET inhibitor with an IC50 value of 2.1 ?M for PCAF. Bromosporine can arrest cell cycle and induce apoptosis in cancer cells. Bromosporine exhibits excellent antitumor activity in xenograft mice model when combined with 5-FU (HY-90006). Bromosporine can increase CDK9 T-loop phosphorylation in HIV-1 latency models, resulting the protection of reactivate HIV-1 replication from latency. Bromosporine can be used to research colorectal cancer, acute myeloid leukemia (AML) and AIDS[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1619994-69-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15815. | |
| CAL-130 Hydrochloride | CAL-130 is a PI3Kδ and PI3Kγ inhibitor with IC 50 s of 1.3 and 6.1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1431697-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16122B. | |
| CC-671 | CC-671 is a dual TTK protein kinase/CDC2-like kinase (CLK2) inhibitor with IC50s of 0.005 and 0.006 ?M for TTK and CLK2, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1618658-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108709. | |
| Celgosivir hydrochloride | Celgosivir hydrochloride (MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC 50 of 1.27 μM in in vitro assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride. CAS No. 141117-12-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16134A. | |
| Cholesterol 24-hydroxylase-IN-1 | Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor ( IC 50 =8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613480-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144309. | |
| Cromolyn | Cromolyn is a mast cell stabilizer. Cromolyn has the potential for the research of bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cromoglicic acid. CAS No. 16110-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1619. | |
| CXCR7 antagonist-1 | CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613021-99-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139643. | |
| Deltarasin hydrochloride | Deltarasin hydrochloride is an inhibitor of KRAS-PDEδ interaction with K d of 38 nM for binding to purified PDE&delta. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613404-76-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15747A. | |
| Desidustat | Desidustat is an orally active HIF hydroxylase inhibitor. Desidustat can be used for the research of various disorders including anemia of different types and conditions associated with ischemia/hypoxia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZYAN1. CAS No. 1616690-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103227. | |
| EIDD-2749 | EIDD-2749 (4'-Fluorouridine) is an orally active RdRp inhibitor. EIDD-2749 effectively blocks the replication of RSV and SARS-CoV-2. EIDD-2749 also exhibits activity against HCV and lymphocytic choriomeningitis virus (LCMV). EIDD-2749 is a promising oral therapeutic candidate for COVID-19 and is also suitable for research on other RNA viruses[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4'-FlU; 4'-Fluorouridine. CAS No. 1613589-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146246. | |
| (-)-Enitociclib | (-)-Enitociclib ((R)-Enitociclib) is an enanthiomer of BAY-1251152 with rotation (-). BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Enitociclib; (-)-BAY-1251152; (-)-VIP152. CAS No. 1610358-59-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-103019B. | |
| (+)-Enitociclib | (+)-Enitociclib ((+)-BAY-1251152) is an enanthiomer of BAY-1251152 with rotation (+). Enitociclib is a potent and selective CDK9 inhibitor with an IC 50 of 3 nM. Enitociclib has anti-tumour activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-BAY-1251152; (+)-VIP152; (S)-Enitociclib. CAS No. 1610358-56-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-103019. | |
| (±)-Enitociclib | (±)-Enitociclib ((±)-BAY-1251152) is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. BAY-1251152 can be used in the study of acute myelogenous leukemia and double-hit diffuse large B-cell lymphoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-BAY-1251152; (±)-VIP152. CAS No. 1610358-53-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103019A. | |
| EPZ015666 | EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 with an IC50 of 22 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK3235025. CAS No. 1616391-65-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12727. | |
| Esomeprazole magnesium | Esomeprazole magnesium ((S)-Omeprazole magnesium) is a potent and orally active H + , K + -ATPase inhibitor. Esomeprazole magnesium has the potential for upper intestinal disorders and gastroesophageal reflux disease research [1] [2]. Esomeprazole magnesium acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H + -ATPases [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Omeprazole magnesium; (-)-Omeprazole magnesium. CAS No. 161973-10-0. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B1446. | |
| Etalocib | Etalocib (LY293111), an orally active leukotriene B 4 receptor antagonist, inhibits the binding of [ 3 H]LTB 4 , with a K i of 25 nM. Etalocib (LY293111) prevents LTB 4 -induced calcium mobilization with an lC 50 of 20 nM. Etalocib (LY293111) induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY293111; VML 295. CAS No. 161172-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13628. | |
| Gartisertib | Gartisertib (VX-803) is an ATP-competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. Gartisertib potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation with an IC50 of 8 nM. Antitumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-803; M4344; ATR inhibitor 2. CAS No. 1613191-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136270. | |
| GSK2801 | GSK2801 is a potent, selective, orally active and cell active acetyl-lysine competitive BAZ2A and BAZ2B bromodomains inhibitor with Kd values of 136 nM and 257 nM, respectively. GSK2801 shows >50-fold selectivity for BAZ2A/B over BRD4[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1619994-68-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15658. | |
| GSK3326595 | GSK3326595 is a protein arginine methyltransferase 5 ( PRMT5 ) inhibitor. GSK3326595 decreases SARS-CoV-2 infection, inhibits cancer cell proliferation and induces pro-inflammatory macrophage polarization and increases hepatic triglyceride levels without affecting atherosclerosis. GSK3326595 can be used for research of relapsed/refractory mantle cell lymphoma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EPZ015938. CAS No. 1616392-22-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-101563. | |
| GSK591 | GSK591 (EPZ015866) is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 4 nM[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EPZ015866; GSK3203591. CAS No. 1616391-87-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100235. | |
| Heptamidine dimethanesulfonate | Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B ( K d =6.9 μM), selectively kills melanoma cells with S100B over those without S100B [1]. Heptamidine is a useful tool for the investigation of Myotonic dystrophy (DM) [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SBi4211 dimethanesulfonate. CAS No. 161374-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16918A. | |
| Hexamethyldisilazane (HMDS) | 500ml Pack Size. Group: Building Blocks, Organics, Stains & Indicators. Formula: C6H19NSi2. CAS No. 999-97-3. Prepack ID 21242140-500ml. Molecular Weight 161.39. See USA prepack pricing. |  |
| HTH-01-015 | HTH-01-015 is a selective NUAK1/ARK5 inhibitor (IC50 is 100 nM). HTH-01-015 inhibits NUAK1 with >100-fold higher potency than NUAK2 (IC50 of >10 ?M). Uses: Scientific research. Group: Signaling pathways. CAS No. 1613724-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12334. | |
| Isobutylmagnesium bromide, 2M solution in diethyl ether | 100ml Pack Size. Group: Analytical Reagents, Building Blocks, Catalysts, Grignard Reagents, Organics. Formula: C4H9BrMg. CAS No. 926-62-5. Prepack ID 90028790-100ml. Molecular Weight 161.32. See USA prepack pricing. | |
| Linsidomine hydrochloride | SIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation [1]. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SIN-1 chloride. CAS No. 16142-27-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101200. | |
| L-Methioninamide hydrochloride | L-Methioninamide hydrochloride, a Methionine analogue, is Methionyl-tRNA synthetase inhibitor [1]. Uses: Scientific research. Group: Peptides. CAS No. 16120-92-6. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W016256. | |
| Luvixasertib hydrochloride | CFI-402257 hydrochloride is a highly selective and orally bioavailable TTK/Mps1 inhibitor with an IC50 of 1.7 nM for TTK in vitro. CFI-402257 hydrochloride has anti-cancer activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CFI-402257 hydrochloride. CAS No. 1610677-37-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101340A. | |
| Luxeptinib | Luxeptinib (CG-806) is an orally active, reversible, first-in-class, non-covalent and potent pan-FLT3/pan-BTK inhibitor. Luxeptinib induces cell cycle arrest, apoptosis or autophagy in acute myeloid leukemia cells[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CG-806. CAS No. 1616428-23-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139535. | |
| LY2857785 | LY2857785 is a type I reversible and competitive ATP kinase inhibitor against CDK9 (IC50 11 nM) and other transcription kinases CDK8 (IC50 16 nM), and CDK7 (IC50 246 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1619903-54-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12293. | |
| MDL 105519 | MDL 105519 is a potent and selective antagonist of glycine binding to the NMDA receptor. Uses: Scientific research. Group: Signaling pathways. CAS No. 161230-88-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15085. | |
| Methoxyfenozide | Methoxyfenozide, a diacylhydrazine insecticide, selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with K d values of 0.5 and 124 nM, respectively. Methoxyfenozide is lethal to neonatal larvae of S. exigua , S. frugiperda , T. ni , O. nubilalis , L. pomonella , H. zea , and H. virescens (LC 50 s=0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively). Uses: Scientific research. Group: Signaling pathways. CAS No. 161050-58-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-117386. | |
| ML318 | ML318 is a novel inhibitor of Pseudomonas aeruginosa PvdQ acylase, an enzyme involved in siderophore pyoverdine synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1610516-67-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C14H8F4N2, Molecular Weight: 280.22. US Biological Life Sciences. | Worldwide |
| ML336 | ML336 is quinazolinone-based inhibitor against venezuelan equine encephalitis virus (VEEV), with IC50s of 32, 20, and 42 nM for VEEV TC-83 CPE , VEEV V3526 CPE, VEEV Wild Type CPE, respectively. ML336 potently inhibits a VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and wild type Trinidad donkey) in the low nanomolar range[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613465-33-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-12928. | |
| ML-336 | ML-336 is a quinazolinone-based inhibitor of Venezuelan Equine Encephalitis Virus (VEEV). It inhibits VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and Trinidad donkey). Synonyms: ML 336; ML336; (E)-2-((1,4-dimethylpiperazin-2-ylidene)-amino)-5-nitro-n-phenylbenzamide. Grades: ≥95%. CAS No. 1613465-33-0. Molecular formula: C19H21N5O3. Mole weight: 367.4. | |
| MT-1207 | MT-1207 is an orally active and selective adrenergic α 1 and 5-HT 2A receptor antagonist. MT-1207 shows IC 50 <0.1 nM, 0.15 nM, 1.40 nM and 0.27 nM for α 1A , α 1B , α 1D and 5-HT 2A , respectively. MT-1207 achieves an effective blood pressure (BP) reduction in the 2K2C rat model without damaging renal function. MT-1207 is a potent multitarget inhibitor with the potential for vasodilatation research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1610794-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162677. | |
| N-Desmethylolanzapine | N-Desmethylolanzapine is an antipsychotic drug. The formation of N-Desmethylolanzapine correlates with the level and activity of human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapine can be used in the study of antipsychotic drugs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Demethylolanzapine; LY170055. CAS No. 161696-76-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W009247. | |
| Netoglitazone | Netoglitazone is a dual agonist of PPARα and PPARγ with antihyperglycemic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCC-555; Isaglitazone. CAS No. 161600-01-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100428. | |
| Nrf2-IN-1 | Nrf2-IN-1 is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2). Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1610022-76-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101025. | |
| Ocifisertib fumarate | CFI-400945 fumarate is a potent, selective and orally bioavailable PLK4 inhibitor with a Ki and an IC50 of 0.26 nM and 2.8 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CFI-400945 fumarate. CAS No. 1616420-30-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12300B. | |
| Ozanimod hydrochloride | Ozanimod (RPC-1063) hydrochloride, a sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity selectively to S1P receptor subtypes 1 (S1P1) and 5 (S1P5). Ozanimod hydrochloride has modulate effect for hS1P 1 and hS1P 5 receptor with EC 50 s of 1.03 nM and 8.6 nM, respectively. Ozanimod hydrochloride can be used for the research of relapsing multiple sclerosis (MS) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RPC-1063 hydrochloride. CAS No. 1618636-37-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12288A. | |
| PCO371 | PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613373-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100856. | |
| Pelcitoclax | Pelcitoclax (APG-1252) is a potent Bcl-2/Bcl-xl inhibitor with antineoplastic and pro-apoptotic effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APG-1252. CAS No. 1619923-36-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109185. | |
| PF-06372865 | PF-06372865 is an orally active, α2/α3/α5 subtype-selective GABA A positive allosteric modulator (PAM). PF-06372865 is a high affinity ligand at GABA A receptors containing α1/α2/α3/α5 subunits ( K i s of 2.9 nM, 21 nM, 134 nM for α2, α1 PAM, α2 PAM, respectively), with low affinity for α4/α6 subunits. PF-06372865 can across the blood-brain barrier (BBB). PF-06372865 has anxiolytic activity and has the potential for epilepsy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1614245-70-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120874. | |
| PF-06726304 | PF-06726304 is a potent and selective EZH2 inhibitor. PF-06726304 inhibits wild-type and Y641N mutant EZH2 with K i s of 0.7 and 3.0 nM, respectively. PF-06726304 displays robust antitumor growth activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1616287-82-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103682. | |
| Plozalizumab | Plozalizumab (MLN-1202) is a specific humanized anti- CCR2 antibody. Plozalizumab can be used for malignant melanoma research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MLN-1202. CAS No. 1610761-46-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99781. | |
| Pregnanediol | Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 1612; NSC 47462. CAS No. 80-92-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107850. | |
| RA190 | RA190, a bis-benzylidine piperidon, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13. Uses: Scientific research. Group: Signaling pathways. CAS No. 1617495-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100739. | |
| Rasagiline mesylate | Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase ( MAO ) inhibitor with IC 50 s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively [1]. Rasagiline (mesylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-AGN1135 mesylate; TVP1012 mesylate. CAS No. 161735-79-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14605. | |
| (R)-PPHT hydrochloride | (R)-PPHT hydrochloride is a potent and selective D2 agonist. Uses: Dopamine agonists. Synonyms: (+/-)-PPHT hydrochloride; 71787-90-1; PPHT hydrochloride; (R)-PPHT hydrochloride; (S)-PPHT hydrochloride; 6-[2-phenylethyl(propyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol; hydrochloride; 159795-62-7; 161757-96-6; (+/-)-2-(N-Phenethyl-N-propyl)amino-5-hydroxytetralin hydrochloride; 6-(Phenethyl(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride; N 0434; (y)-PPHT hydrochloride; (?)-PPHT hydrochloride; EU-0101006; MLS000860001; CHEMBL1256754; DTXSID30474699; Tox21_501006; MFCD00055157; AKOS024418760; CCG-222310; LP01006; NCGC00094300-01; NCGC00261691-01; SMR000326860; NCG-C00094300-01; ( inverted question mark)-PPHT hydrochloride; FT-0757152; P-105; E98624; SR-01000075394; SR-01000075394-1; (+/-)-PPHT hydrochloride, >=98% (HPLC), solid; (+/-)-Ppht hydrochloride(N-0434)potentd2 dopamine re; ( inverted question mark)-2-(N-Phenylethyl)-N-propyl)amino-5-hydroxytetralin hydrochloride; 6-[(2-PHENYLETHYL)(PROPYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALEN-1-OL HYDROCHLORIDE. Grades: 99%. CAS No. 161757-96-6. Molecular formula: C21H27NO.HCl. Mole weight: 345.91. | |
| Seralutinib | Seralutinib (GB002) is an inhaled PDGFRα and PDGFRβ inhibitor. Seralutinib also targets to CSF1R and c-KIT with IC 50 s of 8 nM and 14 nM, respectively. Seralutinib (GB002) is used in the study for pulmonary arterial hypertension [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GB002; PK10571. CAS No. 1619931-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109190. | |
| Seviteronel | Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC 50 =69 nM) and an AR antagonist. Seviteronel demonstrates both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VT-464. CAS No. 1610537-15-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15996. | |
| SGC-CBP30 | SGC-CBP30 is a potent and highly selective CBP/p300 bromodomain (Kds of 21 nM and 32 nM for CBP and p300, respectively) inhibitor, displaying 40-fold selectivity over the first bromodomain of BRD4 [BRD4(1)] bound. SGC-CBP30 strongly reduces secretion of IL-17A in Th17 cells and has anti-inflammatory effects[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613695-14-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15826. | |
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