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| Product | Description | |
|---|---|---|
| ML 179 | ML 179. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| ML 179 | ML 179 is a liver receptor homolog 1 inverse agonist with IC50 value of 320 nM. Synonyms: ML 179; ML179; ML-179; 3-Cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione. Grades: ≥99% by HPLC. CAS No. 1883548-87-5. Molecular formula: C21H25F3N4O2. Mole weight: 422.44. |  |
| 3-(2-Methyl-1,3-dioxolan-2-yl)aniline | 3-(2-Methyl-1,3-dioxolan-2-yl)aniline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(2-methyl-1,3-dioxolan-2-yl)aniline, 51226-14-3, MLS003106499, SBB046404, 3-(2-methyl-1,3-dioxolan-2-yl)phenylamine, NSC159111, methyldioxolanylaniline, AC1Q6ZLR, AC1L6J0R, SureCN3212086, CTK4J3881, MolPort-001-758-585, AR-1E6338, ZINC00410272, AKOS005071450, AG-F-73084, MCULE-3307465494, NSC-159111, RP10841, KB-85810. Product Category: Heterocyclic Organic Compound. CAS No. 51226-14-3. Molecular formula: C10H13NO2. Mole weight: 179.22. Purity: 0.96. IUPACName: 3-(2-methyl-1,3-dioxolan-2-yl)aniline. Canonical SMILES: CC1(OCCO1)C2=CC(=CC=C2)N. Density: 1.151g/cm³. Product ID: ACM51226143. Alfa Chemistry ISO 9001:2015 Certified. |  |
| (3-Aminopropyl)trimethoxysilane | 97%. Uses: Aptms can be multilayered on siox substrates by a layer by layer self assembly. aptms has also been used as a silane coupling agent on silver nanoparticles.aptms is used for the synthesis of gold nano-bipyramids which can be used as substrates for c-reactive protein (crp) antibodies that were detected by localized surface plasmon resonance(lspr). mesoporous silica matrix can be incorporated with aptms for the removal of chromium (cr) from waste water. it can also be used to silanize magnetic iron oxide nanoparticles(mionps) for the separation of cross-linked enzyme aggregations (cleas) from the reaction medium. it may be coated on tio2 to improve the power conversion efficiency (pce) as a critical parameter to assess the overall performance of heterojunction perovskite solar cells (pscs). Group: Saltself-assembly materials. Alternative Names: 3-(Trimethoxysilyl)propylamine. CAS No. 13822-56-5. Pack Sizes: 5 mL/100 mL/500 mL. Product ID: 3-trimethoxysilylpropan-1-amine. Molecular formula: 179.29 g/mol. Mole weight: C6H17NO3Si. CO[Si](CCCN)(OC)OC. InChI=1S/C6H17NO3Si/c1-8-11(9-2, 10-3)6-4-5-7/h4-7H2, 1-3H3. SJECZPVISLOESU-UHFFFAOYSA-N. 0.97. |  |
| 3-Methoxyphenylacetic acid | 3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot [1]. Uses: Scientific research. Group: Natural products. Alternative Names: m-Methoxyphenylacetic acid. CAS No. 1798-09-0. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W015343. |  |
| 4-Isopropylbenzenecarbothioamide | 4-Isopropylbenzenecarbothioamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-isopropylbenzenecarbothioamide, 53515-20-1, AC1Q1OKI, isopropylbenzenecarbothioamide, MLS001004559, AC1M0L75, CTK4J8293, MolPort-002-466-405, 4-propan-2-ylbenzenecarbothioamide, HMS2701I14, ZINC13683884, AKOS002669705, AG-F-83940, BD-0724, MCULE-6998103761, RP10850, 4-(propan-2-yl)benzene-1-carbothioamide, SMR000348179, KB-107689, FT-0680779. Product Category: Heterocyclic Organic Compound. CAS No. 53515-20-1. Molecular formula: C10H13NS. Mole weight: 179.29. Purity: 0.96. IUPACName: 4-propan-2-ylbenzenecarbothioamide. Canonical SMILES: CC(C)C1=CC=C(C=C1)C(=S)N. Density: 1.079g/cm³. Product ID: ACM53515201. Alfa Chemistry ISO 9001:2015 Certified. | |
| Acetyl-CoA Carboxylase-IN-1 | Acetyl-CoA Carboxylase-IN-1 is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC 50 value of ?5 nM. Acetyl-CoA Carboxylase-IN-1 has antibacterial activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179343-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152117. | |
| AR420626 | AR420626 is a selective agonist of free fatty acid receptor 3 ( FFAR3 ) ( IC 50 =117 nM). AR420626 has anti-inflammatory, anticancer and antidiabetic activities. AR420626 improves neurogenic diarrhea by inhibiting nAChR mediated neural pathways. AR420626 inhibits the growth of HepG2 xenografts and inhibits the proliferation of hepatoma cells by inducing apoptosis. AR420626 also suppresses allergic asthma and eczema and has the ability to activate GPR41 to increase Ca 2+ signal-mediated glucose uptake and improve diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1798310-55-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116522. | |
| BAY-876 | BAY-876 is an orally active and selective glucose transporter 1 (GLUT1) inhibitor with an IC 50 of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth. In addition, BAY-876 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799753-84-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100017. | |
| Bortezomib | Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome ( K i =0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PS-341; LDP-341; NSC 681239. CAS No. 179324-69-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10227. | |
| CJ-13,610 | CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC 50 of about 70 nM [1]. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid. Uses: Scientific research. Group: Signaling pathways. CAS No. 179420-17-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106200. | |
| CPCCOEt | CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of metabotropic glutamate receptor 1b (mGluR1b) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179067-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101356. | |
| E-7386 | E-7386 is an orally active CBP/beta-catenin modulator. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799824-08-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111386. | |
| GNF179 | GNF179 exhibits a low clearance (CL=22 ml/min/kg, ~25% of hepatic blood flow in mice), a large volume of distribution (steady-state volume of distribution, Vss=11.8 l/kg), a moderate residence time (MRT=9 hours) and suitable terminal half-life (t1/2=8.9 hours). GNF179 reduced Plasmodium berghei parasitemia levels by 99.7% with a single 100 mg/kg oral dose, and prolonged mouse survival by an average of 19 days. GNF179 was able to protect against an infectious P. berghei sporozoite challenge with a single oral dose at 15 mg/kg while NITD609 was not. Synonyms: GNF 179; GNF-179. Grades: >98%. CAS No. 1261114-01-5. Molecular formula: C22H23ClFN5O. Mole weight: 427.9. | |
| GNF179 Metabolite | GNF179 exhibits a low clearance (CL=22 ml/min/kg, ~25% of hepatic blood flow in mice), a large volume of distribution (steady-state volume of distribution, Vss=11.8 l/kg), a moderate residence time (MRT=9 hours) and suitable terminal half-life (t1/2=8.9 hours). GNF179 reduced Plasmodium berghei parasitemia levels by 99.7% with a single 100 mg/kg oral dose, and prolonged mouse survival by an average of 19 days. GNF179 was able to protect against an infectious P. berghei sporozoite challenge with a single oral dose at 15 mg/kg while NITD609 was not. Synonyms: GNF 179 Metabolite; GNF-179 Metabolite. Grades: >98%. CAS No. 1310455-86-7. Molecular formula: C14H16FN3. Mole weight: 245.3. | |
| GSK-J4 hydrochloride | GSK-J4 hydrochloride is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC 50 s of 8.6 and 6.6 μM, respectively. GSK-J4 hydrochloride inhibits LPS-induced TNF-α production in human primary macrophages with an IC 50 of 9 μM. GSK-J4 hydrochloride is a cell permeable proagent of GSK-J1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1797983-09-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15648F. | |
| HIF-2α-IN-1 | HIF-2α-IN-1 is a HIF-2α inhibitor with an IC50 value of less than 500 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799948-06-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19949. | |
| LXE408 | LXE408 is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 has an IC 50 of 0.04 μM for L. donovani proteasome and an EC 50 of 0.04 μM for L. donovani. LXE408 has a low propensity to cross the blood brain barrier. LXE408 has the potential for visceral leishmaniasis (VL) research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799330-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-131350. | |
| Masupirdine mesylate | Masupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist ( K i of 2.04 nM for human 5-HT6 receptor). Masupirdine mesylate (SUVN-502 mesylate) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SUVN-502 mesylate. CAS No. 1791396-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109118A. | |
| Myricitrin | Myricitrin, a naturally occurring flavonoid, is an orally active nitric oxide (NO) and PKC inhibitor. Myricitrin has central nervous system activity, including anxiolytic-like action. Myricitrin possesses antioxidant, anti-inflammatory, antifibrotic and anti-malarial effects [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 17912-87-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0152. | |
| NCB-0846 | NCB-0846 is an orally active, selective inhibitor for Wnt , that inhibits Traf2- and Nck-interacting kinase ( TNIK ) with an IC 50 of 21?nM. NCB-0846 blocks TGF-β signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1792999-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100830. | |
| Orexin 2 Receptor Agonist | Orexin 2 Receptor Agonist is a potent selective OX2R agonist with an EC 50 of 23 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1796565-52-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19320. | |
| (+)-PD 128907 hydrochloride | (+)-PD 128907 hydrochloride is a selective dopamine D 2 /D 3 receptor agonist, with K i s of 1.7, 0.84 nM for human and rat D 3 receptors, 179, 770 n M for human and rat D 3 receptors, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 300576-59-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110000. | |
| PD150606 | PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor with K i values of 0.21 μM and 0.37 μM for μ- and m-calpains respectively, which is neuroprotective [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179528-45-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100529. | |
| PHCCC | PHCCC is a Group I mGluR antagonist with an IC 50 of 3 μM. PHCCC is a selective positive modulator of mGlu4 receptor. Antiparkinsonian effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179068-02-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100409. | |
| Prucalopride | Prucalopride is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pK i s of 8.6 and 8.1 for human 5-HT4a/4b receptors , respectively. Prucalopride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179474-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14151. | |
| Prucalopride succinate | Prucalopride succinate is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pK i s of 8.6 and 8.1 for human 5-HT4a/4b receptors , respectively. Prucalopride succinate improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride succinate also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride succinate can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-108512. CAS No. 179474-85-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12694. | |
| Pyridalyl | Pyridalyl (S 1812) is an insecticides against Lepidoptera and Thrips. Pyridalyl is less toxic to some beneficial arthropods, and non-target organisms, such as mammals and fish, and thus be utilized in integrated pest management and resistance management [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S 1812. CAS No. 179101-81-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-119779. | |
| Ritlecitinib | Ritlecitinib (PF-06651600) is an orally active and selective JAK3 inhibitor with an IC 50 of 33.1 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-06651600. CAS No. 1792180-81-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-100754. | |
| SDZ 220-581 hydrochloride | SDZ 220-581 hydrochloride is an orally active, potent, competitive NMDA receptor antagonist with pK i value of 7.7 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179411-93-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13059B. | |
| sn-Glycerol 3-phosphate | sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 17989-41-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-113128. | |
| Sumanirole maleate | Sumanirole maleate (U-95666E; PNU-95666E) is a highly selective D2 receptor full agonist with an ED 50 of about 46 nM. Sumanirole plays an important role in the research of Parkinson's disease and restless leg syndrome [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U-95666E; PNU-95666. CAS No. 179386-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70081A. | |
| TD52 | TD52, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p-EGFR inhibition and has potent anti-cancer activity [1]. TD52 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1798328-24-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135699. | |
| Tegafur | Tegafur (FT 207; NSC 148958) is a chemotherapeutic 5-FU proagent used in the treatment of cancers; is a component of tegafur-uracil. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FT 207; NSC 148958. CAS No. 17902-23-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17400. | |
| Titanium diisopropoxide bis(acetylacetonate) | 75 wt. % in isopropanol. Uses: Titanium diisopropoxide bis (acetylacetonate) (taa) may be used as a precursor to develop self assembled macroporous titania particles by evaporation. commercial titanium(iv) bis(acetylacetonate) diisopropoxide was used to synthesize titanium acetylacetonate xerogels by drying, which could be further used to prepare titania films. taa may be used as a hole blocking layer to fabricate solar cells. Group: Perovskite materials solution deposition precursors. Alternative Names: Bis(pentane-2,4-dionato-O,O')bis(propan-2-olato)titanium. CAS No. 17927-72-9. Pack Sizes: 100 mL/500 mL. Molecular formula: 364.26. Mole weight: C16H28O6Ti. 1S/2C5H8O2. 2C3H7O. Ti/c2*1-4(6)3-5(2)7; 2*1-3(2)4; /h2*3, 6H, 1-2H3; 2*3H, 1-2H3; /q; ; 2*-1; +4/p-2/b2*4-3+; ;. OVSGBKZKXUMMHS-VVDZMTNVSA-L. 95%+. | |
| Tolinapant | Tolinapant (ASTX660) is an orally bioavailable dual antagonist of cellular inhibitor of apoptosis protein ( cIAP ) and X-linked inhibitor of apoptosis protein ( XIAP ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASTX660. CAS No. 1799328-86-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109565. | |
| Zearalenone | Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Mycotoxin F2; Toxin F2. CAS No. 17924-92-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103447. | |
| Zotarolimus | Zotarolimus (ABT-578) is a derivative of Rapamycin (HY-10219), with anti-proliferative activity. Zotarolimus is an immunosuppressant. Zotarolimus is developed specifically for local delivery from stents for the prevention of coronary artery restenosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-578; A 179578. CAS No. 221877-54-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12424. | |
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