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| Product | Description | |
|---|---|---|
| ML 204 | ML 204. Group: Biochemicals. Grades: Purified. CAS No. 5465-86-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| ML 204 (Selective TRPC4 Blocker, 4-Methyl-2-(1-piperidinyl)quinoline ) | Blocker of TRPC4 channels (IC50 values are 0.96 and 2.6um in fluorescent and electrophysiological assays, respectively). Exhibits 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5; displays no significant activity at TRPV1, TRPV3, TRPA1 and TRPM8 channels at concentrations up to 22um. Group: Biochemicals. Grades: Highly Purified. CAS No. 5465-86-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ML204 | ML204 is a novel and potential TRPC4 Channel inhibitor. ML204 inhibited TRPC4β-mediated intracellular Ca(2+) rise with an IC(50) value of 0.96 μm and exhibited 19-fold selectivity against muscarinic receptor-coupled TRPC6 channel activation. Synonyms: 4-Methyl-2-piperidin-1-ylquinoline; ML204; ML 204; ML-204. Grades: > 98%. CAS No. 5465-86-1. Molecular formula: C15H18N2. Mole weight: 226.323. |  |
| 1-(7-Ethoxy-1-benzofuran-2-yl)ethanone | 1-(7-Ethoxy-1-benzofuran-2-yl)ethanone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MLS000771990, MolPort-002-466-759, ZINC03887908, CID3868801, SMR000376498, EN300-09789, 58583-72-5. Product Category: Heterocyclic Organic Compound. CAS No. 58583-72-5. Molecular formula: C12H12O3. Mole weight: 204.221880 [g/mol]. Purity: 0.96. IUPACName: 1-(7-ethoxy-1-benzofuran-2-yl)ethanone. Canonical SMILES: CCOC1=CC=CC2=C1OC(=C2)C(=O)C. Density: 1.144g/cm³. Product ID: ACM58583725. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2,2,3,3,3-Pentafluoropropyl acrylate | 2,2,3,3,3-Pentafluoropropyl acrylate. Uses: This product is suitable for scientific research. Group: Self assembly and lithography other materials. Alternative Names: PFPA. CAS No. 356-86-5. Pack Sizes: 5 mL in glass bottle. Product ID: 2,2,3,3,3-pentafluoropropyl prop-2-enoate. Molecular formula: 204.09. Mole weight: H2C=CHCO2CH2CF2CF3. FC(F)(F)C(F)(F)COC(=O)C=C. 1S/C6H5F5O2/c1-2-4(12)13-3-5(7, 8)6(9, 10)11/h2H, 1, 3H2. JDVGNKIUXZQTFD-UHFFFAOYSA-N. ≥ 97%. |  |
| 2,4-Pentanedione,3-[(4-hydroxyphenyl)methylene]- | 2,4-Pentanedione,3-[(4-hydroxyphenyl)methylene]-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NSC643146, MLS000756813, p-Hydroxy-.beta.. beta.-diacetylstyrene, AC1L7FRE, SureCN2026122, HMS2885E08, NSC340305, ZINC00014894, NSC-340305, NSC-643146, SMR000529079, 3-[(4-hydroxyphenyl)methylidene]pentane-2,4-dione, 3-(4-Hydroxybenzylidene)-2,4-pentanedione; p-Hydroxy-.beta.. beta.-diacetylstyrene, 17792-58-4. Product Category: Heterocyclic Organic Compound. CAS No. 17792-58-4. Molecular formula: C12H12O3. Mole weight: 204.2219. Purity: 0.96. IUPACName: 3-[(4-hydroxyphenyl)methylidene]pentane-2,4-dione. Canonical SMILES: CC(=O)C(=CC1=CC=C(C=C1)O)C(=O)C. Density: 1.184g/cm³. Product ID: ACM17792584. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2,7-Dichlorofluorescein diacetate | 2,7-Dichlorofluorescein diacetate (DCFH2-DA) is a cell-permeable fluorescent probe. 2,7-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DCFH2-DA. CAS No. 2044-85-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-126793. |  |
| (2-Aminoethyl)phosphonic acid | (2-Aminoethyl)phosphonic acid is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 2041-14-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W006371. | |
| 4-Hydroxychalcone | 4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity [1]. 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice [2]. Uses: Scientific research. Group: Natural products. CAS No. 20426-12-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-107818. | |
| BCH | BCH (2-Amino-2-norbornanecarboxylic acid) is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Amino-2-norbornanecarboxylic acid; LAT1-IN-1. CAS No. 20448-79-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-108540. | |
| Benzoic acid, 3-(5-methyl-1H-tetrazol-1-yl)- (9CI) | Benzoic acid, 3-(5-methyl-1H-tetrazol-1-yl)- (9CI). Uses: Designed for use in research and industrial production. Additional or Alternative Names: MLS000123618, MolPort-000-873-910, ALBB-005632, ZERO/006384, STK503509, BAS 07016864, SMR000124290, 3-(5-Methyl-tetrazol-1-yl)-benzoic acid, CID3155250, 3-(5-methyl-1H-tetrazol-1-yl)benzoic acid, 799262-37-6. Product Category: Heterocyclic Organic Compound. CAS No. 799262-37-6. Molecular formula: C9H8N4O2. Mole weight: 204.18542. Purity: 0.96. IUPACName: 3-(5-methyltetrazol-1-yl)benzoic acid. Canonical SMILES: CC1=NN=NN1C2=CC=CC(=C2)C(=O)O. Density: 1.46g/cm³. Product ID: ACM799262376. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bis(2-ethylhexyl) sebacate | Bis(2-ethylhexyl) sebacate. CAS No. 122-62-3. Pack Sizes: 250 mL in glass bottle. Product ID: CDC10-0261. Molecular formula: C26H50O4. Category: Cosmetic Plasticizers. Product Keywords: Cosmetic Ingredients; Cosmetic Plasticizers; Bis(2-ethylhexyl) sebacate; CDC10-0261; 122-62-3; C26H50O4; 204-558-8; MFCD00009497; 122-62-3. Purity: 0.9999. Color: Colorless to pale yellow clear. EC Number: 204-558-8. Physical State: Liquid. Quality Level: 100. Storage: 2-8°C. Application: Bis(2-ethylhexyl) sebacate is commonly used as a pressure transmitting fluid (PTF) in hydraulically operated devices, pressure measuring instruments and hydraulic pressure balances. It is also a plasticizing solvent mediator for preparing poly(vinyl chloride) (PVC) based membranes. Boiling Point: 212°C (1 mmHg). Melting Point: -55°C. Density: 0.914 g/cm3. |  |
| Dalcetrapib | Dalcetrapib (JTT-705) is an orally active cholesteryl ester transfer protein (CETP) inhibitor with IC 50 s of 204.6 nM and 6 μM against recombinant human (rh) CETP and human plasma CETP, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JTT-705; RO4607381. CAS No. 211513-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-14950. | |
| Deprodone propionate | Deprodone propionate (RD20000) is a corticosteroid which is obtained by esterifying with propionic acid the 17-position of the prednisolone skeleton and deoxidating its 21-position. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RD20000. CAS No. 20424-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00190. | |
| FPT | FPT, a 2-Aminotetralin, is an efficacious partial agonist at 5-HT 1A R , a full agonist at 5-HT 1B R and 5-HT 1D R with EC 50 s of 39.3 nM, 1.2 nM, 0.5 nM, respectively. FPT is a weak agonist at 5-HT 7 R. FPT shows in vivo efficacy as an antiepileptic in Fmr1 knockout mice and has anxiolytic-like and prosocial effects in Fmr1 knockout mice and other mouse models [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2048491-06-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160887. | |
| GSK963 | GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase , with an IC 50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2049868-46-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103028A. | |
| Indibulin | Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZIO 301; D 24851. CAS No. 204205-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13649. | |
| Kras4B G12D-IN-1 | Kras4B G12D-IN-1 is a Kras4B G12D inhibitor with anticancer effects. Kras4B G12D-IN-1 decreases Kras protein expression in mouse embryonic fibroblasts (MEF) expressing Kras4B G12D (WO2016179558A1, Comp 994566) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2042365-85-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153413. | |
| LLY-283 | LLY-283 is a potent, selective and oral protein arginine methyltransferase 5 ( PRMT5 ) inhibitor, with an IC 50 of 22 nM and a K d of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 2040291-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107777. | |
| Oseltamivir phosphate | Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS 4104 phosphate. CAS No. 204255-11-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17016. | |
| Pexidartinib hydrochloride | Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC 50 s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLX-3397 hydrochloride. CAS No. 2040295-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g; 10 g; 20 g. Product ID: HY-16749A. | |
| Sb 204741 | Sb 204741. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SB 204741, SB204741, 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea, 152239-46-8, AC1MLYNA, Tocris-1372, Lopac-S-0693, SureCN3377716, Lopac0_000255, MLS000862184, S0693_SIGMA, CHEMBL323356, CTK8F0087, N-(1-methyl-5-indolyl)-N-(3-methyl-5-isothiazolyl)urea, HMS2231C03, HMS3260D12, PDSP1_001580, PDSP2_001564, CCG-204350, LP00255. Product Category: Heterocyclic Organic Compound. CAS No. 152239-46-8. Molecular formula: C14H14N4OS. Mole weight: 286.35. Purity: >99 %. IUPACName: 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea. Canonical SMILES: CC1=NSC(=C1)NC(=O)NC2=CC3=C(C=C2)N(C=C3)C. Density: 1.38g/cm³. Product ID: ACM152239468. Alfa Chemistry ISO 9001:2015 Certified. Categories: SB-204741. | |
| SB 204990 | SB 204990 is a potent and specific inhibitor of ATP citrate lyase (ACLY) enzyme. Uses: Scientific research. Group: Signaling pathways. CAS No. 154566-12-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16450. | |
| Seclidemstat mesylate | Seclidemstat (SP-2577) mesylate is a potent noncompetitive and reversible KDM1A (LSD1) inhibitor ( K i =31 nM, IC 50 =13 nM). Seclidemstat mesylate promotes antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, as well as inhibit virus production, viral DNA replication, and late gene expression. Seclidemstat mesylate can be used for the research of Ewing Sarcoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SP-2577 mesylate. CAS No. 2044953-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103713A. | |
| Tecadenoson | Tecadenoson (CVT-510) is a selective A1 adenosine receptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVT-510. CAS No. 204512-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19661. | |
| Terfenadine | Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC 50 of 204 nM [1]. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca 2+ homeostasis. Terfenadine induces ROS-dependent apoptosis , simultaneously activates Caspase-4, -2, -9 [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Terfenadine; MDL-991. CAS No. 50679-08-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1193. | |
| Zafirlukast | Zafirlukast (ICI 204219) is a potent orally active leukotriene D 4 ( LTD 4 ) receptor antagonist. Zafirlukast shows anti-asthmatic, anti-inflammatory and anti-bacterial effects. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI 204219. CAS No. 107753-78-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17492. | |
| Potassium Biphthalate, 0.1 M, Aqueous, Laboratory Grade, 500 mL | Formula: C8H5KO4. Formula Wt: 204. 22. Storage Code: Green; general chemical storage. Uses: Used as a buffer for pH determination. Alternative Names: Potassium hydrogen phthalate, KHP. Grades: chem-grade laboratory. CAS No. 877-24-7. Product ID: 882612. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
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