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| Product | Description | |
|---|---|---|
| ML 221 | ML 221. Group: Biochemicals. Grades: Purified. CAS No. 877636-42-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| 1-Naphthyl PP1 | 1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases and Protein Kinase D. 1-Naphthyl PP1 inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC 50 s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-NA-PP 1. CAS No. 221243-82-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13941. |  |
| 1-NM-PP1 | 1-NM-PP1, a cell-permeable PP1 analog, is a potent Src family kinases inhibitor with IC50s of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PP1 Analog II. CAS No. 221244-14-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13942. | |
| 4,4-Diphenylbutylamine hydrochloride | 4,4-Diphenylbutylamine shows affinity for the 5-HT 2A and H 1 receptors with K i s of 2589 and 1670 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 22101-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141422A. | |
| 5-Amino-3-methylisothiazole-4-carboxylic acid | 5-Amino-3-methylisothiazole-4-carboxylic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MLS000761135, MolPort-002-469-588, MolPort-005-744-375, HMS1783P04, CID152440, SMR000365258, 3-Methyl-5-aminoisothiazolo-4-carboxylic acid, 4-Isothiazolecarboxylic acid, 5-amino-3-methyl-, F2124-0459, 22131-51-7. Product Category: Heterocyclic Organic Compound. CAS No. 22131-51-7. Molecular formula: C5H6N2O2S. Mole weight: 158.177. Purity: 0.96. IUPACName: 5-amino-3-methyl-1,2-thiazole-4-carboxylic acid. Canonical SMILES: CC1=NSC(=C1C(=O)O)N. Density: 1.532g/cm³. Product ID: ACM22131517. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 6-Biopterin | 6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor. Uses: Scientific research. Group: Natural products. Alternative Names: L-Biopterin. CAS No. 22150-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102015. | |
| Cytochalasin D | Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin - cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Zygosporin A; NSC 209835. CAS No. 22144-77-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6682. | |
| Elexacaftor | Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445, Compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-445. CAS No. 2216712-66-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111772. | |
| Ethyl 5-bromo-2-chlorobenzamide | Ethyl 5-bromo-2-chlorobenzamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-bromo-2-chloro-N-ethylbenzamide, ETHYL 5-BROMO-2-CHLOROBENZAMIDE, 150079-92-8, STK225887, MLS000536875, AC1LJHXV, ACMC-209d3p, SureCN7223858, CTK4C6506, Ethyl 5-bromo-2-chlorobenzamide,, MolPort-002-093-682, HMS1593F14, HMS2396A18, ANW-21251, ZINC00616116, AKOS001112167, AG-L-22124, MCULE-4806291250, AK107494, SMR000143522. Product Category: Heterocyclic Organic Compound. CAS No. 150079-92-8. Molecular formula: C9H9BrClNO. Mole weight: 262.5. Purity: 0.97. IUPACName: 5-bromo-2-chloro-N-ethylbenzamide. Product ID: ACM150079928. Alfa Chemistry ISO 9001:2015 Certified. | |
| KAT8-IN-1 | KAT8-IN-1 is a lysine (K) acetyltransferase 8 (KAT8) inhibitor, with IC50s of 141 ?M (KAT8), 221 ?M (KAT2B), 106 ?M (KAT3B), respectively. KAT8 inhibits histone acetyltransferases (HATs), and could result in disease states, such as cancer or inflammatory diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 605-62-9. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W015239. | |
| L-Canavanine sulfate | L-Canavanine sulfate is a selective inhibitor of inducible NO synthase. Uses: Scientific research. Group: Natural products. CAS No. 2219-31-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1581A. | |
| L,L-Dityrosine hydrochloride | L,L-Dityrosine hydrochloride (o,o'-Dityrosine hydrochloride) is a constituent of acid hydrolysates of a number of biological materials, including the insect cuticular resilin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: o,o'-Dityrosine hydrochloride. CAS No. 221308-01-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-101552B. | |
| (-)-Menthol | (-)-Menthol is a key component of peppermint oil that binds and activates transient receptor potential melastatin 8 ( TRPM8 ), a Ca 2+ -permeable nonselective cation channel, to increase [Ca 2+ ] i [1]. Antitumor activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 2216-51-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-75161. | |
| Meso-tetrakis(4-aminophenyl)porphyrin | Meso-tetrakis(4-aminophenyl)porphyrin (IV) is a porphyrin derivative [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 22112-84-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W035136. | |
| ML-193 | ML-193 (CID 1261822) is a potent and selective antagonist of GPR55, with an IC50 of 221 nM. ML-193 shows more than 27-fold selectivity for GPR55 over GPR35, CB1 and CB2. ML-193 can improve the motor and the sensorimotor deficits of Parkinsons disease (PD) rats[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CID 1261822. CAS No. 713121-80-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110125. | |
| MSC1094308 | MSC1094308 is a non-competitive and reversible VPS4B/p97 (VCP) (I/II type AAA ATPase) allosteric inhibitor, with IC50 values of 0.71 ?M and 7.2 ?M for VPS4B and p97, respectively[1]. MSC1094308 inhibits the D2 ATPase activity by binding to a agentable hotspot of p97. MSC1094308 can be used in study of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2219320-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123872. | |
| N-Amidinomorpholine-4-carboxamidine hydrochloride | N-Amidinomorpholine-4-carboxamidine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Flumidin, Influcol, Spenitol, Virusmin, Virustat, Flumadon, ABOB hydrochloride, Moroxydine hydrochloride, Moroxydine HCl, Flumidin (VAN), Prestwick_547, Moroxidine hydrochloride, Morpholinobiguanide hydrochloride, moroxydine monohydrochloride, C6H13N5O.HCl, MLS001032033, MLS002154194, Morpholinobiguanide monohydrochloride, 278610_ALDRICH, EINECS 221-612-6. Product Category: Heterocyclic Organic Compound. CAS No. 7420-18-0. Molecular formula: C6H14ClN5O. Mole weight: 207.661260 [g/mol]. Purity: 0.96. IUPACName: N-(diaminomethylidene)morpholine-4-carboximidamide hydrochloride. Product ID: ACM7420180. Alfa Chemistry ISO 9001:2015 Certified. | |
| (+)-Neomenthol | (+)-Neomenthol is a potent miticide. (+)-Neomenthol shows acaricidal activitie with LD 50 values of 0.32, 0.256 μg/mL for Dermatophagoides farinae and Dermatophagoides pteronyssinus , respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 2216-52-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-135286A. | |
| N-Phenylacrylamide | N-Phenylacrylamide is a special polymer showing high affinity with Ochratoxin A, a colorless and crystalline mycotoxin compound. N-Phenylacrylamide can be applied in the field of mycotoxin extraction, and be used for the security research of agricultural commodities and foods made from cereals and grapes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2210-24-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W018582. | |
| Orforglipron | Orforglipron (LY3502970) (Compound 67) is an orally active agonist for Glucagon-like peptide-1 receptor ( GLP-1R ), which exhibits potency in ameliorates the type 2 diabete [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY3502970; GLP-1 receptor agonist 1. CAS No. 2212020-52-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-112185. | |
| Pinosylvin | Pinosylvin is a pre-infectious stilbenoid toxin isolated from the heartwood of Pinus species, has anti-bacterial activities [1]. Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells [2]. Uses: Scientific research. Group: Natural products. CAS No. 22139-77-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2387. | |
| (R)-Equol | (R)-Equol is an agonist of both ERα and ERβ with K i s of 27.4 and 15.4 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Equol. CAS No. 221054-79-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-108414. | |
| Retosiban | Retosiban (GSK221149A) is a potent and selective oxytocin antagonist with a K i of 0.65 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK 221149; GSK 221149A. CAS No. 820957-38-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14778. | |
| Rheb inhibitor NR1 | Rheb inhibitor NR1 is a Rheb inhibitor with an IC50 of 2.1?μM in the Rheb-IVK assay. Rheb inhibitor NR1 can directly bind Rheb in the switch II domain and selectively inhibit the activation of mechanistic target of rapamycin complex 1 (mTORC1). Rheb inhibitor NR1 inhibits the phosphorylation of mTORC1 driven T389pS6K1 and increases the phosphorylation of S473pAKT in a dose-dependent manner. Rheb inhibitor NR1 does not influence mTORC2 activity[1].(Rheb-IVK: Rheb-dependent mTORC1 kinase activity). Uses: Scientific research. Group: Signaling pathways. CAS No. 2216763-38-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124798. | |
| RO1138452 | RO1138452 is a potent and selective IP (prostacyclin) receptor antagonist. RO1138452 displays high affinity for IP receptors. In human platelets, pKi is 9.3±0.1; in a recombinant IP receptor system, pKi is 8.7±0.06. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CAY10441. CAS No. 221529-58-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108912. | |
| SCH 221510 | SCH 221510 is a potent, orally active and selective NOP (nociceptin opioid receptor) agonist, with an EC 50 of 12 nM and K i of 0.3 nM. SCH 221510 shows an anxiolytic-like effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 322473-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107722. | |
| Spectinomycin dihydrochloride pentahydrate | Spectinomycin dihydrochloride pentahydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride pentahydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride pentahydrate is also a noncompetitive inhibitor of td intron RNA with an K i value of 7.2 mM [1] - [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Spectinomycin hydrochloride hydrate. CAS No. 22189-32-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1828A. | |
| SU0268 | SU0268 is a potent and specific inhibitor of 8-Oxoguanine DNA glycosylase 1 (OGG1). SU0268 regulates inflammatory responses during Pseudomonas aeruginosa infection[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2210228-45-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139056. | |
| Tuberculosis inhibitor 3 | Tuberculosis inhibitor 3 (compound 2i) displays potent anti-TB activity (MIC < 0.016 μg/mL) against agent-sensitive/resistant MTB strains. Tuberculosis inhibitor 3 (compound 2i) shows acceptable PK profiles with oral bioavailability [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2219325-28-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114147. | |
| Zeteletinib | Zeteletinib (BOS-172738; DS-5010) is an orally active, selective RET kinase inhibitor with nanomolar potency against RET and >300-fold selectivity against VEGFR2. Zeteletinib shows exquisite potency for the wild type RET , RET V804M/L gatekeeper mutants, and the most common oncogenic RET mutation M918T. Zeteletinib has potent antitumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BOS-172738; DS-5010. CAS No. 2216753-97-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139590. | |
| Zotarolimus | Zotarolimus (ABT-578) is a derivative of Rapamycin (HY-10219), with anti-proliferative activity. Zotarolimus is an immunosuppressant. Zotarolimus is developed specifically for local delivery from stents for the prevention of coronary artery restenosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-578; A 179578. CAS No. 221877-54-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12424. | |
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