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ML 289 ML 289. Group: Biochemicals. Grades: Purified. CAS No. 1382481-79-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
ML 289 ML-289 is a negative allosteric modulator of mGlu3 with IC50 value of 0.66 μM. It displays 15-fold selectivity over mGlu2 and inactivity against mGlu5.1. Synonyms: VU0463597, VU 0463597, VU-0463597, ML-289, ML 289; ML289; [ (3R) -3- (Hydroxymethyl) -1-pipridinyl][4-[2- (4-methoxyphenyl) ethynyl]phenyl]methanone. Grades: ≥98% by HPLC. CAS No. 1382481-79-9. Molecular formula: C22H23NO3. Mole weight: 349.42. BOC Sciences 10
3-(1-Benzyl-1H-benzimidazol-2-yl)propan-1-ol 3-(1-Benzyl-1H-benzimidazol-2-yl)propan-1-ol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(1-benzyl-1H-benzimidazol-2-yl)propan-1-ol, 121356-81-8, 3-(1-Benzyl-1H-benzoimidazol-2-yl)-propan-1-ol, 3-(1-benzylbenzimidazol-2-yl)propan-1-ol, 3-[1-benzylbenzimidazol-2-yl]propan-1-ol, BAS 00942990, CBMicro_035095, AC1MFJ13, SureCN9740603, Oprea1_289974, Oprea1_417506, MLS001212823, STOCK3S-47798, CTK4B2326, MolPort-000-255-407, HMS2836G06, SBB082386, STK726799, ZINC37866295, AKOS000646979. Product Category: Heterocyclic Organic Compound. CAS No. 121356-81-8. Molecular formula: C17H18N2O. Mole weight: 266.337620 [g/mol]. Purity: 0.96. IUPACName: 3-(1-benzylbenzimidazol-2-yl)propan-1-ol. Canonical SMILES: C1=CC=C(C=C1)CN2C3=CC=CC=C3N=C2CCCO. Density: 1.14g/cm³. Product ID: ACM121356818. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
3,5-Dibenzyloxy benzoic acid 3,5-Dibenzyloxy benzoic acid. Group: Dendrimer building blocks. Alternative Names: 3,5-dibenzyloxybenzoic acid, MLS001195542, Benzoic acid, 3,5-dibenzyloxy-, 3,5-Bis(phenylmethoxy)benzoic acid, EINECS 249-311-5, NSC210283, Benzoic acid, 3,5-bis(phenylmethoxy)-, 3,5-bis(benzyloxy)benzenecarboxylic acid, SMR000550298, TL8005877, 5W-0042, 28917-43-3. CAS No. 28917-43-3. Product ID: 3,5-bis(phenylmethoxy)benzoic acid. Molecular formula: 334.369. Mole weight: C21< / sub>H18< / sub>O4< / sub>. C1=CC=C (C=C1)COC2=CC (=CC (=C2)C (=O)O)OCC3=CC=CC=C3. DHQIBPUGSWVDOH-UHFFFAOYSA-N. >98.0%(T). Alfa Chemistry Materials 7
4-Ethylresorcinol 4-Ethylresorcinol, a derivative of resorcinol, can act as substrates of tyrosinase. 4-Ethylresorcinol possess hypopigmentary effects. 4-Ethylresorcinol attenuates mRNA and protein expression of tyrosinase-related protein (TRP)-2, and possessed antioxidative effect by inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 2896-60-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W015782. MedChemExpress MCE
A-967079 A-967079 is a selective TRPA1 receptor antagonist with IC 50 s of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively, and has good penetration into the CNS. Uses: Scientific research. Group: Signaling pathways. CAS No. 1170613-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108463. MedChemExpress MCE
Arimoclomol maleate Arimoclomol maleate (BRX-220) is an orally active co-inducer of heat shock proteins ( HSP ) [1]. Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system [2].Arimoclomol maleate can be used for the study of Niemann - Pick disease type C. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRX-220. CAS No. 289893-26-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106443A. MedChemExpress MCE
BBO-8520 BBO-8520 is a direct small molecule covalent inhibitor targeting KRAS G12C with high oral availability. BBO-8520 has the characteristics of KRAS G12C (OFF) inhibitor and the function of blocking KRAS G12C (ON) signal. BBO-8520 inhibits cell proliferation by inhibiting KRAS G12C (ON) by binding GTP protein. BBO-8520 can block RAS-RAF1 interaction and return KRAS G12C to the inactive (OFF) state [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2893809-51-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158107. MedChemExpress MCE
Canertinib dihydrochloride Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC 50 s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-1033 dihydrochloride; PD-183805 dihydrochloride. CAS No. 289499-45-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10367A. MedChemExpress MCE
Dalpiciclib hydrochloride Dalpiciclib (SHR-6390) hydrochloride is an orally active and highly selective inhibitor of CDK4 and 6 with IC 50 values of 12.4?nM and 9.9?nM, respectively [1] [2]. Dalpiciclib hydrochloride shows antitumor activity against breast cancer and esophageal squamous cell carcinoma [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHR-6390 hydrochloride. CAS No. 2891598-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114338A. MedChemExpress MCE
E7820 E7820 (ER68203-00), an orally active aromatic sulfonamide derivative, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC 50 of 0.11 μg/ml. E7820 modulates α-1, α-2, α-3, and α-5 integrin mRNA expression. Antiangiogenic and antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ER68203-00. CAS No. 289483-69-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14571. MedChemExpress MCE
L-Allothreonine L-Allothreonine (H-allo-Thr-OH) is an endogenous metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: H-allo-Thr-OH. CAS No. 28954-12-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W008315. MedChemExpress MCE
Mizoribine Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC 50 of approximately 100 μM for anti-HCV activity. Immunosuppressant [1]. Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC 50 s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 289637; HE 69. CAS No. 50924-49-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17470. MedChemExpress MCE
Oridonin Oridonin (NSC-250682), a diterpenoid isolated from Rabdosia rubescens , acts as an inhibitor of AKT , with IC 50 s of 8.4 and 8.9 μM for AKT1 and AKT2; Oridonin possesses anti-tumor, anti-bacterial and anti-inflammatory effects. Uses: Scientific research. Group: Natural products. Alternative Names: NSC-250682; Isodonol. CAS No. 28957-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-N0004. MedChemExpress MCE
PD-L1-IN-2 PD-L1-IN-2 is a potential tumor immunological agent by inhibiting PD-L1. PD-L1-IN-2 is a Naamidine J derivative and exerts antitumor effects in vivo by reducing PD-L1 expression and enhancing tumor-infiltrating T-cell immunity. PD-L1-IN-2 is used for colorectal cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2894733-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149830. MedChemExpress MCE
Pyrimidine Pyrimidine is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 289-95-2. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-Y0519. MedChemExpress MCE
Senicapoc Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca 2+ -activated K + channel; KCa3.1 ) blocker with an IC 50 of 11 nM. Senicapoc blocks Ca 2+ -induced rubidium flux from human RBCs with an IC 50 value of 11 nM and inhibits RBC dehydration with IC 50 of 30 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICA-17043. CAS No. 289656-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50694. MedChemExpress MCE
TBPB TBPB is an allosteric M1 mAChR agonist(EC50=289 nM) that regulates amyloid processing and produces antipsychotic-like activity in rats. Uses: Scientific research. Group: Signaling pathways. CAS No. 634616-95-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14562. MedChemExpress MCE
TN1 TN1 is a potent fetal hemoglobin ( HbF ) inducer. Uses: Scientific research. Group: Signaling pathways. CAS No. 289479-94-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-100826. MedChemExpress MCE
Treprostinil sodium Treprostinil (UT-15) sodium is a potent DP1 and EP2 agonist with EC 50 values of 0.6±0.1 and 6.2±1.2 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UT-15 sodium. CAS No. 289480-64-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16504. MedChemExpress MCE
Ursodeoxycholic acid sodium Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 ( TGR5 , GPCR19 ) and the farnesoid X receptor ( FXR ). Ursodeoxycholic acid sodium can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ursodeoxycholate sodium; Ursodiol sodium; UCDA sodium. CAS No. 2898-95-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-13771A. MedChemExpress MCE
VU0463597 VU0463597, also known as ML-289, is a negative allosteric modulator of mGlu3 (IC50 = 0.66 μM) that displays 15-fold selectivity over mGlu2 and inactivity against mGlu5.1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VU0463597, VU 0463597, VU-0463597, ML-289, ML 289; ML289. Product Category: Others. Appearance: Solid powder. CAS No. 1382481-79-9. Molecular formula: C22H23NO3. Mole weight: 349.43. Purity: >98%. IUPACName: [(3R)-1-({4-[2-(4-methoxyphenyl)ethynyl]phenyl}carbonyl)piperidin-3-yl]methanol. Canonical SMILES: OC[C@H]1CN(C(C2=CC=C(C#CC3=CC=C(OC)C=C3)C=C2)=O)CCC1. Product ID: ACM1382481799. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Watermelon ketone Watermelon ketone is fragrance chemical compound with special odorant which has been widely used in the fragrance industry, extracted from patent CN 103058984 A. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-Methyl-2H-1,5-benzodioxepin-3(4H)-one. CAS No. 28940-11-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W016622. MedChemExpress MCE

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