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| Product | Description | |
|---|---|---|
| ML 297 | ML 297. Group: Biochemicals. Grades: Highly Purified. CAS No. 1443246-62-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| ML 297 | ML 297 is a Kir3.1/3.2 (GIRK1/2) channel activator with IC50 values of 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3. Synonyms: ML297; ML 297; ML-297; N-(3,4-Difluorophenyl)-N'-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea. Grades: ≥99% by HPLC. CAS No. 1443246-62-5. Molecular formula: C17H14F2N4O. Mole weight: 328.32. |  |
| ML 297 | ML 297 (VU 0456810) is a potent and selective GIRK 1/2 activator, with an EC 50 of 0.16 μM. ML 297 is potential for the treatment of epilepsy [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VU 0456810; CID 56642816. CAS No. 1443246-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110192. |  |
| Acetyl-6-formylpterin | Acetyl-6-formylpterin (Ac-6-FP) is a hapten that covalently binds to MR1 through residue Lys43 of the protein, resulting in protein upregulation. Acetyl-6-formylpterin (Ac-6-FP) can be used in the study of inflammation[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ac-6-FP. CAS No. 29769-49-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124004. | |
| Apigenin-7-glucuronide | Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 ?M for MMP-3, MMP-8, MMP-9, MMP-13, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: Apigenin 7-O-glucuronide. CAS No. 29741-09-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N1454. | |
| ATX968 | ATX968 (example 31) is an orally active, potent and selective inhibitor of ATP-dependent RNA helicase A (DHX9), with the EC50 of 0.054 ?M in circBRIP1. ATX968 results in robust and durable tumor growth inhibition or regression in mouse xenograft studies with MSI-H/dMMR colorectal cancer cell lines[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DHX9-IN-2. CAS No. 2973395-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156784. | |
| AVN-944 | AVN-944 (VX-944) is an orally active, potent, selective, noncompetitive and specific inhibitor of IMPDH (inosine monophosphate dehydrogenase). AVN-944 is an essential rate-limiting enzyme in de novo guanine nucleotide synthesis. AVN-944 is also an inhibitor of arenavirus RNA synthesis, and blocks arenavirus infection. AVN-944 has broad anti-cancer activities, and can be used for multiple myeloma (MM) and acute myeloid leukemia (AML) research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-944. CAS No. 297730-17-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13560. | |
| DHX9-IN-1 | DHX9-IN-1 (example 160) is an inhibitor of ATP-dependent RNA helicase A (DHX9) with an EC50 value of 6.94 ?M in cells. DHX9-IN-1 has anti-tumor activity and can be used in the study of DHX9-related cancers[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2973747-89-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-156782. | |
| Ethynodiol diacetate | Ethynodiol diacetate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ethynodiol acetate. CAS No. 297-76-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1089. | |
| Lipofermata | Lipofermata is a fatty acid transport protein 2 (FATP2) inhibitor. Lipofermata shows fatty acid transport inhibition with an IC50 of 4.84 ?M in Caco-2 cells. Lipofermata, an analog of spiro-indoline-thadiazole, shows zinc-specific suppression of antibacterial activity. Lipofermata perturbs zinc homeostasis in E. coli K-12 with a MIC of 16 ?M[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 297180-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116788. | |
| Luteolin 7-O-glucuronide | Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC 50 s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Luteolin 7-glucuronide. CAS No. 29741-10-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N1463. | |
| Mepazine hydrochloride | Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective MALT1 protease inhibitor with IC 50 s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively. Mepazine hydrochloride affects viability of ABC-DLBCL cells by enhancing apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pecazine hydrochloride. CAS No. 2975-36-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-121282A. | |
| Octyl α-D-glucopyranoside | Octyl α-D-glucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 29781-80-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-137313. | |
| Oxyresveratrol | Oxyresveratrol (trans-Oxyresveratrol) is a potent naturally occurring antioxidant and free radical scavenger ( IC 50 of 28.9 μM against DPPH free radicals). Oxyresveratrol is potent and noncompetitive tyrosinase inhibitor with an IC 50 value of 1.2 μM for mushroom tyrosinase. Oxyresveratrol is effective against HSV-1 , HSV-2 and varicella-zoster virus , and has neuroprotective effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: trans-Oxyresveratrol. CAS No. 29700-22-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-N1430. | |
| Suramin sodium salt | Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor [1]. Suramin sodium salt is a potent inhibitor of sirtuins : SirT1 ( IC 50 =297 nM), SirT2 ( IC 50 =1.15 μM), and SirT5 ( IC 50 =22 μM) [2]. Suramin sodium salt is a competitive inhibitor of reverse transcriptase ( DNA topoisomerase II : IC 50 =5 μM) [3] [4]. Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor [5]. Suramin sodium salt efficiently inhibits IP5K and is an antiparasitic , anti-neoplastic and anti-angiogenic agent [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Suramin hexasodium salt. CAS No. 129-46-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0879A. | |
| Teniposide | Teniposide is a podophyllotoxin derivative, acts as a topoisomerase II inhibitor, and used as a chemotherapeutic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VM26. CAS No. 29767-20-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13761. | |
| WHI-P180 | WHI-P180 moderately inhibited ABCG2 function, exhibiting weak phototoxicity. The elimination half-life of WHI-P180 in CD-1 mice (BALB/ c mice) following i.v., i.p., or p.o. administration was less than 10 min. Systemic clearance of WHI-P180 was 6742 mL/h/kg in CD-I mice and 8188 mL/h/kg in BALB/c mice. Notably, WHI-P180, when administered in two consecutive nontoxic i.p. bolus doses of 25 mg/kg, inhibited IgE/antigen-induced vascular hyperpermeability in a well-characterized murine model of passive cutaneous anaphylaxis. Synonyms: WHI-P180; WHI-P-180; WHI-P 180; 3-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol; Janex 3; WHI-P 180; WHIP180. CAS No. 211555-08-7. Molecular formula: C16H15N3O3. Mole weight: 297.31. | |
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