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| Product | Description | |
|---|---|---|
| ML 349 | ML 349. Group: Biochemicals. Grades: Purified. CAS No. 890819-86-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| ML 349 | ML 349 is a lysophospholipase 2 inhibitor with IC50 value of 144 nM. Synonyms: ML349; ML-349; ML 349. (5,5-Dioxido-4H-thieno[3,2-c][1]benzothiopyran-2-yl)[4-(4-methoxyphenyl)-1-piperazinyl]methanone. Grades: ≥98% by HPLC. CAS No. 890819-86-0. Molecular formula: C23H22N2O4S2. Mole weight: 454.56. |  |
| 1-Ethynylpyrene | 1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1 , 1A2 , and 2B1 with IC 50 s of 0.18, 0.32, and 0.04 μM, respectively [1]. 1-Ethynylpyrene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 34993-56-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-131452. |  |
| Alda-1 | Alda-1 is a potent and selective ALDH2 agonist, which activates wild-type ALDH2 and restores near wild-type activity to ALDH2*2. Uses: Scientific research. Group: Signaling pathways. CAS No. 349438-38-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-18936. | |
| Cromakalim | Cromakalim is a potassium channel opener. Cromakalim can be used as a bronchodilator in asthma. Cromakalim inhibits the spontaneous tone of human isolated bronchi in a concentration-related manner being nearly as effective as isoprenaline or theophylline [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 34915. CAS No. 94470-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110011. | |
| HC-030031 | HC-030031 is a potent and selective TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC 50 s of 6.2±0.2 and 5.3±0.2 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 349085-38-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15064. | |
| Kurarinone | Kurarinone is an orally active flavonoid isolated from matrine that inhibits the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting cell differentiation of Th1 and Th17. Kurarinone has antitumor and anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 34981-26-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N2279. | |
| ML 10302 hydrochloride | ML 10302 hydrochloride is a 5-HT4 agonist with EC50 value of 4 nM. It can increase sAPPα levels in the cortex in an animal model of Alzheimer's disease and exhibit progastrokinetic effects in vivo. Synonyms: ML-10302 HCl; ML-10302; ML 10302; ML10302. 4-Amino-5-chloro-2-methoxybenzoic acid 2-(1-piperidinyl)ethyl ester hydrochloride. Grades: ≥99% by HPLC. CAS No. 186826-17-5. Molecular formula: C15H21ClN2O3.HCl. Mole weight: 349.25. | |
| ML 289 | ML-289 is a negative allosteric modulator of mGlu3 with IC50 value of 0.66 μM. It displays 15-fold selectivity over mGlu2 and inactivity against mGlu5.1. Synonyms: VU0463597, VU 0463597, VU-0463597, ML-289, ML 289; ML289; [ (3R) -3- (Hydroxymethyl) -1-pipridinyl][4-[2- (4-methoxyphenyl) ethynyl]phenyl]methanone. Grades: ≥98% by HPLC. CAS No. 1382481-79-9. Molecular formula: C22H23NO3. Mole weight: 349.42. | |
| ML324 | ML324 exhibits good Caco-2 cell permeability, and possesses excellent microsomal stability in the presence of both mouse and rat liver microsomes. Synonyms: ML-324; ML 324; ML324; CID-44143209; CID 44143209; CID44143209. Grades: >98%. CAS No. 1222800-79-4. Molecular formula: C21H23N3O2. Mole weight: 349.43. | |
| NNC-711 | NNC-711 is a potent and selective inhibitor of GAT-1 (GABA transporter 1) with IC 50 values of 0.04, 0.38, 171, 1700, 349, 622 μM for human GAT-1, rat GAT-1, rGAT-2, hGAT-3, rGAT-3, hBGT-3, respectively. NNC-711 has anticonvulsant and analgesic effect in vivo and exhibits cognition-enhancing activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NO-711 hydrochloride. CAS No. 145645-62-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-103506. | |
| VU0463597 | VU0463597, also known as ML-289, is a negative allosteric modulator of mGlu3 (IC50 = 0.66 μM) that displays 15-fold selectivity over mGlu2 and inactivity against mGlu5.1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VU0463597, VU 0463597, VU-0463597, ML-289, ML 289; ML289. Product Category: Others. Appearance: Solid powder. CAS No. 1382481-79-9. Molecular formula: C22H23NO3. Mole weight: 349.43. Purity: >98%. IUPACName: [(3R)-1-({4-[2-(4-methoxyphenyl)ethynyl]phenyl}carbonyl)piperidin-3-yl]methanol. Canonical SMILES: OC[C@H]1CN(C(C2=CC=C(C#CC3=CC=C(OC)C=C3)C=C2)=O)CCC1. Product ID: ACM1382481799. Alfa Chemistry ISO 9001:2015 Certified. |  |
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