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ML 354. Group: Biochemicals. Grades: Purified. CAS No. 89159-60-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ML 354
ML 354 is a selective PAR4 antagonist with IC50 value of 140 nM. Synonyms: ML354; ML-354; ML 354; VU0099704; VU-0099704; VU 0099704; 1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol. Grades: ≥98% by HPLC. CAS No. 89159-60-4. Molecular formula: C16H14N2O3. Mole weight: 282.29.
3-Aminobenzamide
3-Aminobenzamide (PARP-IN-1) is a potent inhibitor of PARP with IC 50 of appr 50 nM in CHO cells, and acts as a mediator of oxidant-induced myocyte dysfunction during reperfusion. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PARP-IN-1. CAS No. 3544-24-9. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-12022.
9-Amino-6-chloro-2-methoxyacridine
9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H + /solute antiport system [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: ACMA. CAS No. 3548-9-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-118155.
Allyl methyl carbonate
Allyl methyl carbonate. Uses: Employed in the pd(0)-mediated synthesis of allyl aryl ethers and sulfides, and α,β-unsaturated carbonyls. Group: Monomers. Alternative Names: Methyl allyl carbonate. CAS No. 35466-83-2. Pack Sizes: Packaging 5, 25 mL in glass bottle. Product ID: methyl prop-2-enyl carbonate. Molecular formula: 116.12. Mole weight: CH2=CHCH2OCOOCH3. COC(=O)OCC=C. 1S/C5H8O3/c1-3-4-8-5(6)7-2/h3H, 1, 4H2, 2H3. YHLVIDQQTOMBGN-UHFFFAOYSA-N.
Alverine citrate
Alverine citrate is a 5-HT 1A receptor antagonist, with an IC 50 of 101 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 35459. CAS No. 5560-59-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0500.
Bendamustine hydrochloride
Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDX-105. CAS No. 3543-75-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0077.
Chrysomycin a
Chrysomycin A (Chr-A), an antibiotic, can be obtained from Streptomyces. Chrysomycin A exhibits antitumor and anti-tuberculous and MRSA activities. As for glioblastoma, Chrysomycin A inhibits the proliferation, migration, and invasion of cancer cells through the Akt/GSK-3β/β-catenin signaling pathway. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Albacarcin V, MLS002701849, NSC354844, 1,5-anhydro-6-deoxy-1-(8-ethenyl-1-hydroxy-10,12-dimethoxy-6-oxo-6h-dibenzo[c,h]chromen-4-yl)-3-c-methylhexitol, 82196-88-1, VIRENOMYCIN V, AC1Q6MMD, AC1L3VB3, KST-1B9536, AR-1B8017, NSC613946, NSC 354844, NSC-354844, NSC-613946, NCI60_003193, SMR001565441, 4-(6-Deoxy-3-C-methyl-.beta.-gulopyranosyl)-8-vinyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]. Product Category: Inhibitors. CAS No. 82196-88-1. Molecular formula: C28H28O9. Mole weight: 508.52. Purity: 0.96. IUPACName: 8-ethenyl-1-hydroxy-10,12-dimethoxy-4-(3,4,5-trihydroxy-4,6-dimethyloxan-2-yl)naphtho[1,2-c]isochromen-6-one. Canonical SMILES: CC1C(C(C(C(O1)C2=C3C(=C(C=C2)O)C(=CC4=C3OC(=O)C5=CC(=CC(=C54)OC)C=C)OC)O)(C)O)O. Density: 1.405g/cm³. Product ID: ACM82196881. Alfa Chemistry ISO 9001:2015 Certified. Categories: Chrysomyinae.
Cyamemazine
Cyamemazine is a neuroleptic agent that contains the phenothiazine chromophore. Cyamemazine is often used as an anxiolytic. Cyamemazine is a potent 5-HT 3 ( K i of 12 nM), 5-HT 2A ( K i = 1.5 nM) and 5-HT 2C ( K i of 75 nM) receptors antagonist with antipsychotic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3546-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14264.
Ebrotidine
Ebrotidine(FI 3542) is a competitive H2-receptor antagonist (Ki= 127. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FI3542. CAS No. 100981-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15538.
Methyl p-tert-butylphenylacetate
Methyl p-tert-butylphenylacetate is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 3549-23-3. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W018501.
Midecamycin
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria. Uses: Scientific research. Group: Natural products. Alternative Names: SF-837; Antibiotic SF-837. CAS No. 35457-80-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1908.
MLS1547
MLS1547 is a highly efficacious D2 dopamine receptor (D2R) G protein-biased agonist that does not recruit β-arrestin, and is an antagonist of dopamine-stimulated β-arrestin recruitment to the D2 receptor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MLS1547; MLS-1547; MLS 1547; MLS000051547. Product Category: Agonists. Appearance: Solid powder. CAS No. 315698-36-3. Molecular formula: C19H19ClN4O. Mole weight: 354.84. Purity: >98%. IUPACName: 5-Chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol. Canonical SMILES: OC1=C2N=CC=CC2=C(Cl)C=C1CN3CCN(C4=NC=CC=C4)CC3. Product ID: ACM315698363. Alfa Chemistry ISO 9001:2015 Certified.
MLS 1547
MLS 1547 is a dopamine D2 receptor agonist. It may be used in the combination with antipsychotic drugs. Synonyms: MLS 1547; MLS1547; MLS-1547; 5-Chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol. Grades: ≥98% by HPLC. CAS No. 315698-36-3. Molecular formula: C19H19ClN4O. Mole weight: 354.83.
A cell-permeable (quinoxalinyl methyl idene-D-Tryptophanyl) hydrazide that directly targets Rho GEF binding domain (Kd = 354nM for RhoA), thereby prevents Rho from interacting with its GEFs (including LARG, DBL, LBC, p115 RhoGEF, and PDZ RhoGEF), but not p190RhoGAP, RhoGDI, or its effectors (ROCK, mDia, PKN, Rhoteckin). Shown to inhibit serum-induced RhoA, RhoB, and RhoC, but not Cdc42 or Rac1, activation, MLC & PAK phosphorylation, as well as stress fiber & focal complex formation in serum-starved NIH3T3 cultures (Effective conc. 30uM) in a reversible manner. Group: Biochemicals. Grades: Highly Purified. CAS No. 1173671-63-0. Pack Sizes: 25mg. Molecular Formula: C??H??N?O, Primary Target: Rho GTPase. US Biological Life Sciences.
Worldwide
SC-514
SC-514 is a selective IKK-2 inhibitor ( IC 50 =11.2 μM), which does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GK 01140. CAS No. 354812-17-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13802.
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