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ML-180 ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1) that inhibits cell proliferation. Synonyms: ML 180; ML180; CID-3238389; SR1848; 6-[4-(3-Chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione. Grades: ≥98%. CAS No. 863588-32-3. Molecular formula: C20H25ClN4O2. Mole weight: 388.9. BOC Sciences 9
ML-180 ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2 ) inverse agonist with an IC 50 of 3.7 μM. ML-180 is inactive for steroidogenic factor-1 (SF-1; NR5A1 ; IC 50 >10 μM). ML-180 has the potential for LRH-1-dependent cancers [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR1848. CAS No. 863588-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-115613. MedChemExpress MCE

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