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| Product | Description | |
|---|---|---|
| ML-7 | ML-7 is a potent and selective inhibitor of myosin light chain(MLC) kinase with Ki value of 0.3 μM. It has been shown to protect cardiac function from ischemia/reperfusion (I/R) injury. It inhibts smooth-muscle myosin light chain kinase, protein kinase C (PKC) and cAMP-dependent protein kinase (PKA). Uses: Ml-7 hydrochloride has been shown to protect cardiac function from ischemia/reperfusion (i/r) injury. Synonyms: ML7; ML 7; 1-[(5-iodo-1-naphthyl)sulfonyl]-1,4-diazepane. Grades: >98%. CAS No. 109376-83-2. Molecular formula: C15H17IN2O2S. Mole weight: 416.28. |  |
| ML-7 | powder. Group: Fluorescence/luminescence spectroscopy. |  |
| ML-7 hydrochloride | ML-7 Hcl is a cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM). It also inhibt smooth-muscle myosin light chain kinase, protein kinase C (PKC) and cAMP-dependent protein kinase (PKA). Synonyms: ML-7 HCl; ML-7 hydrochloride; ML-7; ML 7; ML7. Grades: >98%. CAS No. 110448-33-4. Molecular formula: C15H18ClIN2O2S. Mole weight: 452.74. | |
| ML-7 hydrochloride | ML-7 hydrochloride is a naphthalene sulphonamide derivative, potently inhibits MLCK ( IC 50 =300 nM). ML-7 hydrochloride also inhibits YAP/TAZ. Uses: Scientific research. Group: Signaling pathways. CAS No. 110448-33-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15417. |  |
| ML-7, Hydrochloride - CAS 110448-33-4 | A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM). Group: Fluorescence/luminescence spectroscopy. | |
| Protein Kinase Inhibitor ML-7 (PKI) (1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride) | Inhibits myosin light chain kinase. Group: Biochemicals. Alternative Names: 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride. Grades: Molecular Biology Grade. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4 -diazepine, hydrochloride | 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4 -diazepine, hydrochloride. Group: Biochemicals. Alternative Names: ML-7; Hexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-1H-1,4-diazepine monohydrochloride. Grades: Highly Purified. CAS No. 110448-33-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C15H18ClIN2O2S. US Biological Life Sciences. | Worldwide |
| ML 786 dihydrochloride | ML786 dihydrochloride is a Raf kinase inhibitor with IC50 values are 2.1, 2.5 and 4.2 nM for B-RafV600E, C-Raf and wild-type B-Raf respectively. It may be used in novel cancer therapies in the future. Synonyms: MLN786 Dihydrochloride; MLN-786 Dihydrochloride; MLN 786 Dihydrochloride; MLN786 2HCl; MLN-786 2HCl; MLN 786 2HCl; 3-(1-Amino-1-methylethyl)-N-[(2R)-1,2,3,4-tetrahydro-7-oxo-1,8-naphthryridin-4-yl)oxy]-2-naphthalenyl]-5-benzamide dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1237536-18-3. Molecular formula: C29H29F3N4O3.2HCl. Mole weight: 611.48. | |
| MLT-747 | MLT-747 is a potent and selective malt1 peptide cleavage inhibitor. Synonyms: AC-31545; HY-124587; MLT 747; MLT747. Grades: ≥98% by HPLC. CAS No. 2097853-86-4. Molecular formula: C20H21Cl2N7O3. Mole weight: 478.3. | |
| MLT-748 | MLT-748 is a potent and selective malt1 peptide cleavage inhibitor. Synonyms: 1-(5-Chloro-6-(2H-1,2,3-Triazol-2-Yl)Pyridin-3-Yl)-3-(2-Chloro-7-((1R,2R)-1,2-Dimethoxypropyl)Pyrazolo[1,5-A]Pyrimidin-6-Yl)Urea. Grades: ≥98% by HPLC. CAS No. 1832578-30-9. Molecular formula: C19H19Cl2N9O3. Mole weight: 492.3. | |
| TAK-243 | TAK-243, a pyrazolopyrimidine derivative, has been found to be an Ubiquitin-protein ligase inhibitor and was just finished the Phase-I trial against solid tumors. Synonyms: TAK-243; TAK 243; TAK243; MLN7243; MLN-7243; MLN 7243; AOB87172; AOB-87172; AOB 87172. Grades: 98%. CAS No. 1450833-55-2. Molecular formula: C19H20F3N5O5S2. Mole weight: 519.51. | |
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