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| Product | Description | |
|---|---|---|
| ML241 | ML241 is a selective p97 ATPase inhibitor and IC50 value is 100 nM. It can inhibit degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the treatment of cancer. Uses: Anticancer. Synonyms: 2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-5,6,7,8-tetrahydroquinazolin-4-amine; ML241; ML-241; ML 241. Grades: 98%. CAS No. 1346528-06-0. Molecular formula: C23H24N4O. Mole weight: 372.46. |  |
| ML241 HCl | ML241 is identified as a potent and selective inhibitors of p97 ATPase (IC(50)= 100 nM). ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 could impair the endoplasmic-reticulum-associated degradation (ERAD) pathway. Synonyms: 2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-5,6,7,8-tetrahydroquinazolin-4-amine hydrochloride; ML241; ML-241; ML 241; ML241 HCl; ML241 hydrochloride. CAS No. 2070015-13-1. Molecular formula: C23H25ClN4O. Mole weight: 408.93. | |
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