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| Product | Description | |
|---|---|---|
| ML264 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| ML264 | ML264 is a Krüppel-like factor 5 (KLF5) inhibitor with the potential to inhibits growth of colorectal cancer. It reduces EGR1 and KLF5 levels so that ML264 inhibits the MAPK pathway. in a cell-based assay for proliferation of DLD-1 cells: IC50 = 29 nM, in. Synonyms: (E)-3-(3-chlorophenyl)-N-[2-[(1,1-dioxothian-4-yl)-methylamino]-2-oxoethyl]prop-2-enamideML264; ML264; ML 264; MLS003874889SCHEMBL15605936SCHE MBL17045845CS-5628; CS 5628; CS5628HY-19994; HY 19994; HY19994SMR002531696SR-03000002171SR-03000002171-1(E)-3-(3-chlorophenyl)-N-(2-((1,1-dioxidotetrahydro-. CAS No. 1550008-55-3. Molecular formula: C17H21ClN2O4S. Mole weight: 384.88. |  |
| ML264 | ML264 is an antitumor agent that potently and selectively inhibits Krüppel-like factor five ( KLF5 ) expression. Uses: Scientific research. Group: Signaling pathways. CAS No. 1550008-55-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19994. |  |
| SR18662 | SR18662 is an optimized anticancel agent based on ML264. SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo. SR18662 showed improved efficacy in reducing the viability of multiple colorectal cancer cell lines. Flow cytometry analysis following SR18662 treatment showed an increase in cells captured in either S or G2-M phases of the cell cycle and a significant increase in the number of apoptotic cells, the latter a unique property compared with ML264 or SR15006. SR18662 treatment also reduces the expression of cyclins and components of the MAPK and WNT signaling pathways. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SR18662; SR-18662; SR 18662. Product Category: Others. Appearance: Solid powder. CAS No. 2505001-62-5. Molecular formula: C16H19Cl2N3O4S. Mole weight: 420.31. Purity: >98%. IUPACName: (E)-3-(3,4-dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide. Canonical SMILES: O=C(NCC(N1CCN(S(=O)(C)=O)CC1)=O)/C=C/C2=CC=C(Cl)C(Cl)=C2. Product ID: ACM2505001625. Alfa Chemistry ISO 9001:2015 Certified. |  |
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